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Condition: Septic Shock
Procedure: Anesthesia

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Total 20 results found since Jan 2013.

The impact of hypoalbuminemia on postoperative outcomes after outpatient surgery: a national analysis of the NSQIP database
CONCLUSIONS: Hypoalbuminemia is associated with major complications and death in outpatient surgery. Since hypoalbuminemia is a potential modifiable intervention, future clinical trials to evaluate the impact of optimizing preoperative albumin levels before outpatient surgery are warranted.PMID:35761062 | DOI:10.1007/s12630-022-02280-7
Source: Canadian Journal of Anaesthesia - June 27, 2022 Category: Anesthesiology Authors: Sean Curran Patricia Apruzzese Mark C Kendall Gildasio De Oliveira Source Type: research

Machine learning methods to improve bedside fluid responsiveness prediction in severe sepsis or septic shock: an observational study, British journal of anaesthesia
Conclusions: Machine learning generated several models for predicting fluid responsiveness that were comparable with the haemodynamic response to PLR.
Source: Current Awareness Service for Health (CASH) - May 6, 2021 Category: Consumer Health News Source Type: news

Left ventricular-arterial coupling as a predictor of stroke volume response to norepinephrine in septic shock – a prospective cohort study
This study aims t...
Source: BMC Anesthesiology - February 17, 2021 Category: Anesthesiology Authors: Xiaoyang Zhou, Jianneng Pan, Yang Wang, Hua Wang, Zhaojun Xu and Weibo Zhuo Tags: Research article Source Type: research

Idarucizumab for dabigatran reversal in daily clinical practice: A case series
CONCLUSION Our first experiences with idarucizumab use in daily-care settings support a rapid and efficient decrease in the anticoagulant effect of dabigatran in emergency situations. Late re-occurrence of dabigatran effect was noted in a subset of patients with severe renal failure.
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Pneumocephalus and pneumorachis after blunt chest trauma without spinal fractures: a case report
ConclusionsThis is the first case report to describe pneumorachis and pneumocephalus following blunt trauma with pneumothorax, but no spinal or skull fractures. The mechanism that is probably involved here is a migration of air with subcutaneous emphysema and a pleural hernia into the spinal canal. However, in cases of pneumorachis or pneumocephalus, skull fractures need to be investigated as these require surgery and appropriate vaccination to prevent meningitis.
Source: Journal of Medical Case Reports - October 24, 2019 Category: General Medicine Source Type: research

Challenge to the Intestinal Mucosa During Sepsis
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with ...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research

Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier
We examined a possible protective effect of OX-A against LPS-induced ROS formation and microglia activation. To mimic in vitro the connection between gut and brain and to study the putative effect on the cortical microglia, we used a co-culture of Caco-2 cells and primary cortical microglia with Caco-2 cells placed at the apical side of a transwell and primary cortical microglia at the basolateral side. All treatments used to study the apical vs. basal connection were applied to the apical compartment. We used DHR (10 μM, 20 min), a cell-permeable fluorogenic probe useful for the detection of ROS formation, to dete...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research

A Study of Convulsive Status Epilepticus Cases in Indonesia
Publication date: Available online 14 March 2019Source: Epilepsy & Behavior Case ReportsAuthor(s): Machlusil Husna, K. Shahdevi Nandar, Risma Karlina Prabawati, Siti NurlaelaAbstractStatus epilepticus (SE) is a serious health issue in developing countries, with high morbidity and mortality rates of 3%–46%. There are two types of SE, convulsive status epilepticus (CSE) and non-convulsive status epilepticus. The most common type, CSE, is easy to detect but, in several cases, the patients are diagnosed too late to be properly treated and hospitalized. The present study therefore investigated the clinical manifestations of C...
Source: Epilepsy and Behavior Case Reports - March 16, 2019 Category: Neurology Source Type: research

Postoperative Complications Affecting Survival After Cardiac Arrest in General Surgery Patients.
CONCLUSIONS: Among general surgery patients with cardiac arrest after POD #0, complications occurring before cardiac arrest are common but are not associated with increased mortality risk. PMID: 28891912 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - September 7, 2017 Category: Anesthesiology Authors: Kim M, Li G Tags: Anesth Analg Source Type: research

Risk Stratification for Major Postoperative Complications in Patients Undergoing Intra-abdominal General Surgery Using Latent Class Analysis.
CONCLUSIONS: LCA can be used to classify patients undergoing intra-abdominal general surgery based on preoperative risk factors, and the classes are independently associated with postoperative complications. However, model performance is not uniform across individual complications, resulting in variations in the utility of preoperative risk stratification tools depending on the complication evaluated. PMID: 28806210 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - August 10, 2017 Category: Anesthesiology Authors: Kim M, Wall MM, Li G Tags: Anesth Analg Source Type: research

Predicting Fluid Responsiveness in Acute Liver Failure: A Prospective Study.
CONCLUSIONS: PPV based on pulse contour analysis predicted fluid responsiveness in ALF. PMID: 27984249 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - December 13, 2016 Category: Anesthesiology Authors: Audimoolam VK, McPhail MJ, Willars C, Bernal W, Wendon JA, Cecconi M, Auzinger G Tags: Anesth Analg Source Type: research

A Rational Approach to Fluid Therapy in Sepsis
(Abstracted from Br J Anaesth, 116:339–349, 2016) The current standard of care for managing patients with severe sepsis and septic shock is aggressive fluid resuscitation, until a central venous pressure of greater than 8 mm Hg is achieved. The rationale behind this approach is to increase a patient’s stroke volume, which in turn improves cardiac output and organ perfusion.
Source: Survey of Anesthesiology - November 19, 2016 Category: Anesthesiology Tags: Critical Care Source Type: research