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Total 5383 results found since Jan 2013.
Life-Space Mobility: Normative Values from a National Cohort of U.S. Older Adults
CONCLUSIONS: We report US national norms for LSA among community-dwelling Black and White older adults. These norms can serve as a reference tool for determining if clinical and research samples have greater or lesser life-space mobility than typical older adults in the US for their age and sex.PMID:37480583 | DOI:10.1093/gerona/glad176
Source: Biol Sci Space - July 22, 2023 Category: Science Authors: Alexander X Lo Virginia G Wadley Cynthia J Brown D Leann Long Michael Crowe Virginia J Howard Richard E Kennedy Source Type: research
How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the breaking point.
“The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally.
Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news
Astrocytes in Post-Stroke Depression: Roles in Inflammation, Neurotransmission, and Neurotrophin Signaling
Cell Mol Neurobiol. 2023 Jul 20. doi: 10.1007/s10571-023-01386-w. Online ahead of print.ABSTRACTPost-stroke depression (PSD) is a frequent and disabling complication of stroke that affects up to one-third of stroke survivors. The pathophysiology of PSD involves multiple mechanisms, including neurochemical, neuroinflammatory, neurotrophic, and neuroplastic changes. Astrocytes are a type of glial cell that is plentiful and adaptable in the central nervous system. They play key roles in various mechanisms by modulating neurotransmission, inflammation, neurogenesis, and synaptic plasticity. This review summarizes the latest ev...
Source: Cellular and Molecular Neurobiology - July 20, 2023 Category: Cytology Authors: Dongqing Jing Xiaoli Hou Xiao Guo Xin Zhao Kexin Zhang Jingwen Zhang Chengxia Kan Fang Han Junling Liu Xiaodong Sun Source Type: research
Liver function test indices-based prediction model for post-stroke depression: a multicenter, retrospective study
Post-stroke depression (PSD) was one of the most prevalent and serious neuropsychiatric effects after stroke. Nevertheless, the association between liver function test indices and PSD remains elusive, and ther...
Source: BMC Medical Informatics and Decision Making - July 19, 2023 Category: Information Technology Authors: Jun Gong, Yalian Zhang, Xiaogang Zhong, Yi Zhang, Yanhua Chen and Huilai Wang Tags: Research Source Type: research
Comparative study of ultrasonic-guided betamethasone local injection and extracorporeal shock wave therapy in post-stroke hemiplegic shoulder pain: a randomized clinical trial
ConclusionThe ultrasonic-guided betamethasone local injection and extracorporeal shock wave both can improve hemiplegic shoulder pain. However, the UGLI can induce a more cytokine expression level.
Source: Frontiers in Neurology - July 19, 2023 Category: Neurology Source Type: research
Reminiscence therapy relieves anxiety, depression and boosts spiritual well-being in both stroke patients and their spouse caregivers: a randomized, controlled study
ConclusionsRT relieves anxiety, depression and boosts spiritual well-being in both stroke patients and their spouse caregivers.
Source: Irish Journal of Medical Science - July 19, 2023 Category: General Medicine Source Type: research
Scientists Are Just Beginning to Understand COVID-19 ’ s Effect On the Brain
Early in the COVID-19 pandemic, doctors started to notice something striking. For what was originally described as a respiratory virus, SARS-CoV-2 seemed to have a strong effect on the brain, causing everything from loss of taste and smell and brain fog to, in serious cases, stroke.
NYU Langone Health, a New York city research hospital, started collating those anecdotes in hopes of better understanding how the virus affects the brain and nervous system. Years later, the project has morphed from focusing solely on acute symptoms to also tracking the long-term neurologic issues that some people with Long COVID experience, sa...
Source: TIME: Health - July 17, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
The structured ambulatory post-stroke care program for outpatient aftercare in patients with ischaemic stroke in Germany (SANO): an open-label, cluster-randomised controlled trial
This study was registered with the German Clinical Trials Register, DRKS00015322.FINDINGS: Between Jan 1, 2019 and Dec 22, 2020, 36 clusters were assessed for eligibility, of which 30 were randomly assigned to the intervention group (n=15 clusters) or control group (n=15 clusters). No clusters dropped out of the study. 1203 (86%) of 1396 enrolled patients in the intervention group and 1283 (92%) of 1395 enrolled patients in the control group were included in the mITT population. The primary endpoint was confirmed in 64 (5·3%) of 1203 patients in the intervention group and 80 (6·2%) of 1283 patients in the control group (...
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Christopher J Schwarzbach Felizitas Anna Eichner Viktoria R ücker Anna-Lena Hofmann Moritz Keller Heinrich J Audebert Stephan von Bandemer Stefan T Engelter Dieter Geis Klaus Gr öschel Karl Georg Haeusler Gerhard F Hamann Andreas Meisel Dirk Sander Mart Source Type: research
Using MemTrax memory test to screen for post-stroke cognitive impairment after ischemic stroke: a cross-sectional study
ConclusionMemTrax (MTx) is valid and effective for screening for PSCI among target patients and is a potentially valuable and practical tool in the clinical follow-up, monitoring, and case management of PSCI.
Source: Frontiers in Human Neuroscience - July 17, 2023 Category: Neuroscience Source Type: research
Identification of a miRNA –mRNA regulatory network for post-stroke depression: a machine-learning approach
ConclusionThe study highlighted gene signatures for PSD with three genes (SPATA2, ZNF208, and YTHDC1) and four upstream miRNAs (miR-6883-5p, miR-6873-3p, miR-4776-3p, and miR-6738-3p). These biomarkers could further our understanding of the pathogenesis of PSD.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
Herbal medicine as adjunctive therapy with antidepressants for post-stroke depression: a systematic review and network meta-analysis of randomized controlled trials
This study summarizes the latest evidence regarding the harms and benefits of herbal antidepressants.Methods: The literature searched from the Cochrane Library (using the OVID platform), Embase, PubMed, the China National Knowledge Infrastructure (CNKI), the Wan Fang Data Knowledge Service Platform, and the China Scientific Journal Database (VIP) from their inception to 18 August 2021, for randomized controlled trials of herbal medicine in adults with post-stroke depression, were included in this systematic review and network meta-analysis. The search was updated on 1 December 2022. To summarize the evidence, the frequenti...
Source: Frontiers in Pharmacology - July 14, 2023 Category: Drugs & Pharmacology Source Type: research
