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Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Successful endovascular recanalization of a partially occluded basilar artery fenestration.
Authors: Meinel TR, Pult F, Gralla J, Arnold M, Bassetti C, Jung S Abstract A 76-year-old man with a history of arterial hypertension, obstructive sleep apnea, dyslipidemia, family history of cardiovascular events, prestroke and overweight presented 90 minutes after acute onset of right-sided sensorimotor hemiparesis, hemiataxia and dysarthria (National Institutes of Health Stroke Scale (NIHSS) 9/42). Magnetic resonance imaging (MRI) revealed a pontine ischemia and MR angiography showed a thrombus in the middle to distal portion of the basilar artery. Owing to the location, an occlusion of one lumen of a fenestrate...
Source: Interventional Neuroradiology - August 11, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Is obstructive sleep apnea associated with the presence of intracranial cerebral atherosclerosis?
CONCLUSIONS: Our findings suggest that moderate to severe OSA is associated with the presence of ICAS in patients with suspected OSA. PMID: 28168435 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 6, 2017 Category: Sleep Medicine Authors: Song TJ, Park JH, Choi KH, Kim JH, Choi Y, Chang Y, Kim HJ, Moon J, Kim YJ, Lee HW Tags: Sleep Breath Source Type: research

Biomarkers of Cardiovascular Stress in Obstructive Sleep Apnea
Publication date: Available online 2 July 2016 Source:Clinica Chimica Acta Author(s): Micha T. Maeder, Christian Mueller, Otto D. Schoch, Peter Ammann, Hans Rickli Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder associated with “cardiovascular stress”, i.e. cardiovascular risk factors, cardiovascular diseases, and an increased risk of heart failure, stroke, and death. Experimental and clinical studies have characterized potential underlying mechanisms including biventricular dysfunction, atherosclerosis, and arrhythmia. Assessment of these cardiovascular features of OSA requires a spec...
Source: Clinica Chimica Acta - July 1, 2016 Category: Laboratory Medicine Source Type: research

Biomarkers of Cardiovascular Stress in Obstructive Sleep Apnea.
Abstract Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder associated with "cardiovascular stress", i.e. cardiovascular risk factors, cardiovascular diseases, and an increased risk of heart failure, stroke, and death. Experimental and clinical studies have characterized potential underlying mechanisms including biventricular dysfunction, atherosclerosis, and arrhythmia. Assessment of these cardiovascular features of OSA requires a spectrum of clinical tools including ECG, echocardiography, exercise testing, and angiography. In contrast to many cardiovascular diseases, the role of blood bio...
Source: International Journal of Clinical Chemistry - July 1, 2016 Category: Chemistry Authors: Maeder MT, Mueller C, Schoch OD, Ammann P, Rickli H Tags: Clin Chim Acta Source Type: research

Wake-up stroke in a young woman with rotational vertebral artery occlusion due to far-lateral cervical disc herniation.
Abstract Wake-up stroke is most likely to be caused by small-vessel disease, and is related to snoring. The authors present a rare case of far-lateral cervical disc herniation with neck rotation, resulting in wake-up stroke in a young woman. The patient, a 31-year-old woman, was admitted to the hospital because of dysarthria and confusion when she awoke in the morning. Brain MRI showed acute infarction in the posterior fossa. Cerebral angiography showed thrombus in the distal top of the basilar artery and the bilateral posterior cerebral arteries. During angiography, the thrombus size decreased with heparinization...
Source: Journal of Neurosurgery.Spine - May 1, 2015 Category: Neurosurgery Authors: Okawa M, Amamoto T, Abe H, Yoshimura S, Higashi T, Inoue T Tags: J Neurosurg Spine Source Type: research

Recurrent ischemic strokes and headaches originating from Lambl's excrescence (P2.273)
CONCLUSIONS: The association between recurrent strokes and late-age onset migraine with aura should raise clinical suspicion of a cardiogenic valvular etiology. Early TEE use is necessary to diagnose cardiac valvular strands like LE. LE associated with migraine headaches should prompt a treatment with anti-thrombotic agent. While anticoagulants and cardiothoracic surgery are indicated for recurrent strokes, a combined antiplatelet therapy was effective in our patient.Disclosure: Dr. Dumitrascu has nothing to disclose. Dr. Tsimerinov has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Dumitrascu, O., Tsimerinov, E. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research