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Anticoagulation following mitral valve repair
ConclusionsOur analysis showed that postoperative warfarin use was associated with an overall reduced composite of bleeding and thromboembolic incidents and superior long ‐term survival. These findings suggest that anticoagulation with warfarin following mitral valve repair may be a safe and effective means for avoiding postoperative complications and that a large prospective randomized clinical trial is warranted.
Source: Journal of Cardiac Surgery - October 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Tessa M. F. Watt, Shannon L. Murray, Alexander A. Brescia, David A. Burn, Alexander Wisniewski, Shazli P. Khan, Matthew A. Romano, Steven F. Bolling, The Michigan Mitral Research Group (MMRG) Tags: ORIGINAL ARTICLE Source Type: research

Almost 20% Of Nonsmoking Workers Are Exposed To Secondhand Smoke On The Job, Study Finds
(CNN) — People who don’t smoke can still be at risk for heart disease, lung cancer and stroke after they’re exposed to secondhand smoke. Almost 20% of nonsmoking workers in the United States were exposed to secondhand smoke while on the job, according to a study published Thursday by the US Centers for Disease Control and Prevention. During 2013 and 2014, 1 in 4 US nonsmokers reported a secondhand smoking exposure and an estimated 41,000 adult nonsmokers’ deaths were linked to secondhand smoke. “Secondhand smoke exposure is an important public health issue … and has been recognized as on...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 12, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN secondhand smoke Smoking Source Type: news

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Delayed Surgical Management of Type A Intramural Hematoma Is Not Associated with Worse Outcomes Than Emergent Operation.
CONCLUSIONS: In well-selected patients, delayed operation for type An intramural hematoma is not associated with adverse outcomes. PMID: 31013218 [PubMed - in process]
Source: The Heart Surgery Forum - March 3, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Zhou X, Krishnan A, Hsu J, Burns A, Mandal K Tags: Heart Surg Forum Source Type: research

Long Distance Running Effects On Your Health
Long distance running is becoming more and more popular. Close to two million people every year drag themselves across the finish lines. And that’s just in half marathon races. Runners in these 13.1 mile events have increased six-fold over the past 25 years.  All these amateur athletes think they’re getting really healthy as they work themselves up to full marathons. But the truth is they are cutting years off their life.  You can see it for yourself if you stand at the finish line of any race. The hardcore runners look terrible. They look gaunt and malnourished. They are hunched over and have a stiff awkwa...
Source: Al Sears, MD Natural Remedies - June 20, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Fitness Source Type: news

Golf and Wellness: Enjoy Your Health in Full Swing
On June 11, 2016, over 3,000 properties in 83 countries will celebrate Global Wellness Day with the objective to touch the hearts and minds of 250 million people. Thousands of wellness activities will be organized, free of charge, by day spas and salons, hotel spas, fitness clubs, yoga/Pilates studios, ballet companies and dance schools, town halls, even golf clubs. Millions of people will be given the opportunity to try new fun and healthy activities, experience new sensations as bodies are pleasantly invited to breathe consciously, stretch to one's heart content, walk the talk, hike to discover new horizons, pack a scrum...
Source: Healthy Living - The Huffington Post - April 7, 2016 Category: Consumer Health News Source Type: news

Endothelial necrosis at 1 hour postburn predicts progression of tissue injury
Abstract Burn injury progression has not been well characterized at the cellular level. To define burn injury progression in terms of cell death, histopathologic spatiotemporal relationships of cellular necrosis and apoptosis were investigated in a validated porcine model of vertical burn injury progression. Cell necrosis was identified by high mobility group box 1 protein and apoptosis by Caspase 3a staining of tissue samples taken 1 hour, 24 hours, and 7 days postburn. Level of endothelial cell necrosis at 1 hour was predictive of level of apoptosis at 24 hours (Pearson's r = 0.87) and of level of tissue necrosis at ...
Source: Wound Repair and Regeneration - April 29, 2013 Category: Surgery Authors: Douglas Hirth, Steve A. McClain, Adam J. Singer, Richard A. F. Clark Tags: Original Research‐Basic Science Source Type: research

Stem Cells for Cell-Based Therapies
The world of stem cells We know the human body comprises many cell types (e.g., blood cells, skin cells, cervical cells), but we often forget to appreciate that all of these different cell types arose from a single cell—the fertilized egg. A host of sequential, awe-inspiring events occur between the fertilization of an egg and the formation of a new individual: Embryonic stem (ES) cells are also called totipotent cells. The first steps involve making more cells by simple cell division: one cell becomes two cells; two cells become four cells, etc. Each cell of early development is undifferentiated; that is, it is...
Source: ActionBioscience - December 28, 2012 Category: Science Authors: Ali Hochberg Source Type: news