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Current Landscape of Therapeutics for the Management of Hypertension - A Review
Curr Drug Deliv. 2023 Jun 23. doi: 10.2174/1567201820666230623121433. Online ahead of print.ABSTRACTHypertension is a critical health problem. It is also the primary cause of coronary heart disease, stroke, and renal vascular disease. The use of herbal drugs in the management of any disease is increasing. They are considered the best immune booster to fight against several types of diseases. To date, the demand for herbal drugs has been increasing because of their excellent properties. This review highlights antihypertensive drugs, polyphenols, and synbiotics for managing hypertension. Evidence is mounting in favour of mor...
Source: Current Drug Delivery - June 26, 2023 Category: Drugs & Pharmacology Authors: Neda Fatima Sumel Ashique Aakash Upadhyay Shubneesh Kumar Himanshu Kumar Nitish Kumar Prashant Kumar Source Type: research

Safety and efficacy of stenting for symptomatic intracranial artery stenosis: a systematic reveiw and meta-analysis
Conclusion: Studies suggest that stenting combined with medication for patients with sICAS may increase the incidence of death or stroke, cerebral haemorrhage, stroke or death, but has no significant effect on the incidence of TIA and stroke. The studies report inadequate and conflicting data and therefore the safety and efficacy of stenting for sICAS should be interpreted with caution.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022377090, identifier CRD42022377090
Source: Frontiers in Pharmacology - June 8, 2023 Category: Drugs & Pharmacology Source Type: research

Effects of comprehensive care measures based on the HAPA model on self-care, neurotransmitters and clinical outcomes in cerebral infarction patients
CONCLUSIONS: Comprehensive care measures of HAPA model may be used with advantage to improve the self-care ability, reduce the degree of neurological damage, and improve neurological function in cerebral infarction patients. Age, hypertension history, and NIHSS score after treatment were all risk factors related to poor prognosis.PMID:37259727 | DOI:10.26355/eurrev_202305_32452
Source: European Review for Medical and Pharmacological Sciences - June 1, 2023 Category: Drugs & Pharmacology Authors: X-H Tian X Chen G-F Jiang Source Type: research

Attenuating lipid metabolism in atherosclerosis: The potential role of Anti-oxidative effects on low-density lipoprotein of herbal medicines
Atherosclerosis (AS) is a multifactorial chronic disease with great harm to the health of human being, which is a basic pathogenesis of many cardiovascular diseases and ultimately threatens human life. Abnormal blood lipid level is one of the most common diagnostic indicators of AS in clinic, and lipid metabolism disorder is often observed in patients with AS. Cholesterol is an important lipid in the human body, which is of great significance for maintaining normal life activities. Generally, cholesterol is transported to peripheral tissues by low-density lipoprotein (LDL), and then transported to the liver by high-density...
Source: Frontiers in Pharmacology - March 31, 2023 Category: Drugs & Pharmacology Source Type: research

Superior Stroke Prevention with Angiotensin Receptor Blockers Compared with Other Antihypertensive Drugs
Expert Opin Drug Saf. 2023 Mar 7. doi: 10.1080/14740338.2023.2189236. Online ahead of print.ABSTRACTINTRODUCTION: Stroke is a major cause of death and disability and its incidence is linearly increased with the elevation of blood pressure (BP) and the advancement of age in both men and women, with its incidence being higher in older subjects, the blacks and women.AREAS COVERED: The annual worldwide incidence of stroke is 7.6 million for subjects ≥ 20 years of age with the average direct and indirect annual costs of stroke care, is expected to be $94.3 billion between 2014 and 2015. With respect to the cause of stroke, th...
Source: Expert Opinion on Drug Safety - March 7, 2023 Category: Drugs & Pharmacology Authors: Steven G Chrysant Source Type: research

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