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Condition: Heart Disease
Management: Electronic Health Records (EHR)

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Total 155 results found since Jan 2013.

Systolic blood pressure, chronic obstructive pulmonary disease and cardiovascular risk
Conclusion Using deep learning for modelling EHR, we identified a monotonic association between SBP and risk of cardiovascular events in patients with COPD.
Source: Heart - July 27, 2023 Category: Cardiology Authors: Rao, S., Nazarzadeh, M., Li, Y., Canoy, D., Mamouei, M., Salimi-Khorshidi, G., Rahimi, K. Tags: Open access Cardiac risk factors and prevention Source Type: research

Associations of Serum 25(OH)D with Risk of Recurrent Cardiovascular Events in Individuals with Coronary Heart Disease
This study aimed to investigate the associations of serum 25-hydroxyvitamin D [25(OH)D] concentration and the vitamin D receptor (VDR) polymorphisms with the risk of recurrent cardiovascular events in individuals with established CHD.METHODS: A total of 22,571 participants with CHD were included from the UK Biobank. Recurrent cardiovascular events, including myocardial infarction (MI), heart failure (HF), stroke, and CVD mortality, were identified from electronic health records. Cox proportional hazard models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).RESULTS: The median (interquartile ra...
Source: The Journal of Clinical Endocrinology and Metabolism - June 6, 2023 Category: Endocrinology Authors: Xiaoyu Lin Xue Chen Sen Liu Yulei Deng Yuexuan Wang Qi Lu Rui Li Yunjing Ou Qingying Tian Yunfei Liao Guanglin Cui Kun Yang An Pan Gang Liu Source Type: research

Outcome of transcatheter atrial septal defect closure in a nationwide cohort
CONCLUSION: After TC closure of ASD, patients had a higher risk of new-onset atrial fibrillation and migraine than controls without ASD. As novel findings, we found an increased risk for ischemic heart disease, AV conduction disorders, and ventricular fibrillation/tachycardia.Key messagesEven though patients have an excellent overall prognosis after percutaneous ASD closure, the increased incidence of major comorbidities like atrial fibrillation and heart failure prompts more thorough lifelong follow-up.This study's novel findings revealed the increased risk for ischemic heart disease, AV conduction disorders, or ventricul...
Source: Annals of Medicine - February 14, 2023 Category: Internal Medicine Authors: V Muroke M Jalanko J Haukka J Hartikainen A Tahvanainen H Ukkonen K Ylitalo J Pihkala J Sinisalo Source Type: research

Effectiveness of Simvastatin Versus Gemfibrozil for Primary Prevention of Cardiovascular Events: A Retrospective Cohort Study of 223,699 Primary Care Patients
ConclusionThe results of this study showed better population-level effectiveness of simvastatin compared with gemfibrozil for the primary prevention of MACE; however, a definitive randomized controlled trial is required to compare simvastatin with gemfibrozil among patients with low HDL cholesterol, as they appear to obtain benefit with gemfibrozil.
Source: Clinical Drug Investigation - October 14, 2022 Category: Drugs & Pharmacology Source Type: research

Comparative Risks of Nonsteroidal Antiinflammatory Drugs on Cardiovascular Diseases: A Population-Based Cohort Study
This article is protected by copyright. All rights reserved.PMID:36063443 | DOI:10.1002/jcph.2142
Source: The Journal of Clinical Pharmacology - September 5, 2022 Category: Drugs & Pharmacology Authors: Eric Yuk Fai Wan Esther Yee Tak Yu Linda Chan Anna Hoi Ying Mok Yuan Wang Esther Wai Yin Chan Ian Chi Kei Wong Cindy Lo Kuen Lam Source Type: research

Vitamin D status, genetic factors, and risk of cardiovascular disease among individuals with type 2 diabetes: a prospective study
CONCLUSIONS: Higher serum 25(OH)D concentrations were significantly associated with lower risks of total CVD and IHD among patients with T2D, regardless of genetic susceptibility and genetic variants in VDR. Risk reductions tended to plateau at serum 25(OH)D levels around 50 nmol/L. These findings suggest that maintaining adequate vitamin D status and avoiding deficiency may help to prevent CVD complications among patients with T2D.PMID:35771998 | DOI:10.1093/ajcn/nqac183
Source: The American Journal of Clinical Nutrition - June 30, 2022 Category: Nutrition Authors: Zhenzhen Wan Tingting Geng Rui Li Xue Chen Qi Lu Xiaoyu Lin Liangkai Chen Yanjun Guo Liegang Liu Zhilei Shan An Pan JoAnn E Manson Gang Liu Source Type: research

Long-term exposure to ozone and cardiovascular mortality in a large Chinese cohort
CONCLUSIONS: We observed the association between long-term exposure to high O3 concentrations and cause-specific CVD mortality in China, independent of PM2.5 and other CVD risk factors. This suggested an urgent need to control O3 pollution, especially in developing countries.PMID:35605364 | DOI:10.1016/j.envint.2022.107280
Source: Environment International - May 23, 2022 Category: Environmental Health Authors: Shudan Liu Yi Zhang Runmei Ma Xiaofei Liu Jingyuan Liang Hongbo Lin Peng Shen Jingyi Zhang Ping Lu Xun Tang Tiantian Li Pei Gao Source Type: research

Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits
Conclusions and Relevance: The hazard of incident cardiovascular disease is higher in those receiving eiASMs. The association is dose dependent and the absolute difference in hazard seems to reach clinical significance by approximately 10 years from first exposure.PMID:35444497 | PMC:PMC8988723 | DOI:10.1177/15357597211070392
Source: Epilepsy Curr - April 21, 2022 Category: Neurology Authors: David G Vossler Source Type: research