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Total 11296 results found since Jan 2013.

Predictive performance of CHA2DS2-VASc-HS score and Framingham risk scores for coronary disease severity in ischemic heart disease patients with invasive coronary angiography
CONCLUSIONS: Our study demonstrated a high predictive performance of coronary artery injury using the CHA2DS2-VASc-HS score and Framingham risk scores. These scores could be applied in predicting ischemic heart disease in non-symptomatic cases where invasive coronary angiography is not indicated.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-abstract-4.jpg.PMID:37667940 | DOI:10.26355/eurrev_202308_33415
Source: European Review for Medical and Pharmacological Sciences - September 5, 2023 Category: Drugs & Pharmacology Authors: A-V Tran K-D Nguyen K-D Nguyen A-T Huynh B-L-T Tran T-H Ngo Source Type: research

Causal relationship between Alzheimer's disease and cardiovascular disease: a bidirectional Mendelian randomization analysis
This study applied a two-sample bidirectional Mendelian randomization method to explore the causal relationship between CVD and AD. Genome-wide association study (GWAS) data from 46 datasets of European populations (21,982 cases of AD and 41,944 controls) were utilized to obtain genetic instrumental variables for AD. In addition, genetic instrumental variables for atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI), coronary heart disease (CHD), angina pectoris (AP), and ischemic stroke (IS) (including large-artery atherosclerotic stroke [LAS] and cardioembolic stroke [CES]) were selected from GWAS dat...
Source: Aging - September 4, 2023 Category: Biomedical Science Authors: Fengjun Zhang Dexian Xian Junchen Feng Luning Ning Tianshou Jiang Wenchang Xu Yuan Liu Qiong Zhao Min Peng Source Type: research

Efficacy of ablation therapy on clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
CONCLUSION: Ablation significantly reduces the risk of stroke, cardiovascular mortality, all-cause mortality, and HF in AF patients, compared with medical therapy alone, supporting its use in clinical practice.PMID:37663739 | PMC:PMC10473299 | DOI:10.1097/MS9.0000000000000985
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Mohammad Munim Zahoor Saad Ehsan Ullah Harriet Mmaitsi Kidiavai Shahda A H Eltieb Anjuli Devi Muhammad Anis Asif Akshay Vaswani Ammar Hyder Muhammad Roshan Hoti Sayed Jawad Sana Arshid Abhirami Shankar Muhammad Salman Source Type: research

What Are the Complications of Sickle Cell Trait?
Discussion Sickle cell disease (SCD) is a group of inherited blood disorders where there are abnormal hemoglobin molecules and the red blood cells take on a characteristic sickled shape instead of a rounded shape. Sickled hemoglobin provides an evolutionary advantage of giving the individual increased protection against severe and cerebral malaria. The sickled shape doesn’t move through the vascular system as well and therefore is more likely to aggregate in small vessels causing an increased risk of vaso-occlusive disease, acute chest syndrome, splenic sequestration, and priapism. There is also an increased risk of ...
Source: PediatricEducation.org - September 4, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Temporal trends of hypertrophic cardiomyopathy in Denmark: a nationwide retrospective cohort study
Conclusion There was a consistent rise in HCM cases with decreasing morbidity burden. Females were older at diagnosis and more likely to have their type of HCM classified as obstructive. The rate of outpatient follow-up is increasing.
Source: BMJ Open - September 4, 2023 Category: General Medicine Authors: Zörner, C. R., Pallisgaard, J., Schjerning, A.-M., Jensen, M. K., Tonnesen, J., Da Riis-Vestergaard, L., Middelfart, C., Rasmussen, P. V., Gislason, G., Hansen, M. L. Tags: Open access, Cardiovascular medicine Source Type: research

Negative correlation between organ heteroplasmy, particularly hepatic heteroplasmy, and age at death revealed by post-mortem studies of m.3243A & gt; G cases
Mol Genet Metab. 2023 Aug 28;140(3):107691. doi: 10.1016/j.ymgme.2023.107691. Online ahead of print.ABSTRACTMitochondrial DNA m.3243A > G mutation causes mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) and its associated multi-organ disorders, including diabetes. To clarify associations between m.3243A > G organ heteroplasmy and clinical phenotypes, including the age at death, we combined genetic and pathological examinations from seven unreported and 36 literature cases of autopsied subjects. Clinical characteristics of subjects were as follows: male, 13; female, 28; unknown, 2; the a...
Source: Molecular Medicine - September 3, 2023 Category: Molecular Biology Authors: Kunimasa Yagi Satoko Okazaki Azusa Ohbatake Masako Nakaya Jianhui Liu Eiko Arite Yukiko Miyamoto Naoko Ito Kaoru Nakano Naoto Yamaaki Hisae Honoki Shiho Fujisaka Daisuke Chujo Shin-Ichiro Tsunoda Kunio Yanagimoto Tsuyoshi Nozue Masayo Yamada Kotaro Ooe Ts Source Type: research

Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: This MR study provided evidence supporting the causal effect of T1DM on peripheral atherosclerosis and coronary atherosclerosis, with hypertension partly mediating this effect.PMID:37659996 | DOI:10.1186/s12933-023-01974-6
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Zirui Liu Haocheng Wang Zhengkai Yang Yu Lu Cao Zou Source Type: research

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