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Standardized acquisition and post-processing of dynamic susceptibility contrast perfusion in patients with brain tumors, cerebrovascular disease and dementia: comparability of post-processing software.
CONCLUSION: Despite a highly standardized workflow, parametric perfusion maps are depended on the chosen software. Radiologists should consider software related variances when using dynamic susceptibility contrast perfusion for clinical imaging and research. ADVANCES IN KNOWLEDGE: This multicenter study compared perfusion parameters calculated by two commercial dynamic susceptibility contrast perfusion post-processing software solutions in different central nervous system disorders with a large sample size and a highly standardized processing workflow. Despite, parametric perfusion maps are depended on the chosen soft...
Source: The British Journal of Radiology - October 15, 2019 Category: Radiology Authors: Schmidt M, Knott M, Hoelter P, Engelhorn T, Elna Marie L, Than N, Marco E, Doerfler A Tags: Br J Radiol Source Type: research

One of Britain's youngest stroke victims at just 19 months 'stands up' for the first time
Ronnie Kerman, of Bransholme, was found lifeless in his cot in March 2018 by his father. He is receiving chemotherapy for a brain tumour which caused the stroke and left him unable to use his legs.
Source: the Mail online | Health - June 14, 2019 Category: Consumer Health News Source Type: news

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1 1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Toddler became one of Britain's youngest stroke victims caused by a mysterious brain tumour
Ronnie Kerman was found 'unresponsive' and 'floppy' in his cot at just 19 months old on February 2 this year by his father Phil, 40. He was rushed to Hull Royal Infirmary and then transferred to Leeds.
Source: the Mail online | Health - September 28, 2018 Category: Consumer Health News Source Type: news

Comparison of two stroke volume variation-based goal-directed fluid therapies for supratentorial brain tumour resection: a randomized controlled trial
ConclusionsDuring GDFT for supratentorial brain tumour resection, fluid boluses targeting a lower SVV are more beneficial than a restrictive protocol.Clinical trial registrationNCT02113358.
Source: British Journal of Anaesthesia - July 17, 2017 Category: Anesthesiology Source Type: research