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Condition: Heart Attack
Procedure: Kidney Transplant

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Total 141 results found since Jan 2013.

Stimulator of interferon genes (STING): Key therapeutic targets in ischemia/reperfusion injury
Biomed Pharmacother. 2023 Sep 10;167:115458. doi: 10.1016/j.biopha.2023.115458. Online ahead of print.ABSTRACTThe Stimulator of Interferon Genes (STING) is predominantly expressed in immune cells, including macrophages, natural killer cells, dendritic cells, and T cells, functioning as a pattern recognition receptor. STING activation upon detecting cytosolic DNA released from damaged cells initiates downstream pathways, leading to the production of inflammatory cytokines such as IFNs, IL-6, and TNF-α. Dysregulated STING activation has been implicated in inflammatory and metabolic diseases. Ischemia/reperfusion injury (I/R...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 12, 2023 Category: Drugs & Pharmacology Authors: Juan Lv Xuanxuan Zhu Chunlei Xing Yuhong Chen Huihui Bian Heng Yin Xiaofeng Gu Li Su Source Type: research

Screening and Management of Coronary Artery Disease in Kidney Transplant Candidates
Diagnostics (Basel). 2023 Aug 20;13(16):2709. doi: 10.3390/diagnostics13162709.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD), especially in end-stage renal disease (ESRD) patients and during the first year after transplantation. For these reasons, and due to the shortage of organs available for transplant, it is of utmost importance to identify patients with a good life expectancy after transplant and minimize the transplant peri-operative risk. Various conditions, such as severe pulmonary diseases, recent myocardial infarction or stroke, and ...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Giuseppe Vadal à Chiara Alaimo Giancarlo Buccheri Luca Di Fazio Leandro Di Caccamo Vincenzo Sucato Manlio Cipriani Alfredo Ruggero Galassi Source Type: research

Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme
CONCLUSION: Globally, CKD carries a significant economic burden, which increases substantially with increasing disease severity. We identified significant gaps in published costs and inconsistent costing definitions. Cost-effective interventions that target primary prevention and disease progression are essential to reduce CKD burden. Our results can be used to guide cost collection and facilitate better comparisons across countries/regions to inform healthcare policy.PMID:37493856 | DOI:10.1007/s12325-023-02608-9
Source: Adv Data - July 26, 2023 Category: Epidemiology Authors: Vivekanand Jha Saeed M G Al-Ghamdi Guisen Li Mai-Szu Wu Panagiotis Stafylas Lise Retat Joshua Card-Gowers Salvatore Barone Claudia Cabrera Juan Jose Garcia Sanchez Source Type: research

Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
CONCLUSIONS: There is currently insufficient evidence to determine the effectiveness of ACEi or ARB in patients with stage 1 to 3 CKD who do not have DM. The available evidence is overall of very low certainty and high risk of bias. We have identified an area of large uncertainty for a group of patients who account for most of those diagnosed as having CKD.PMID:37466151 | DOI:10.1002/14651858.CD007751.pub3
Source: Cochrane Database of Systematic Reviews - July 19, 2023 Category: General Medicine Authors: Tess E Cooper Claris Teng David J Tunnicliffe Brydee A Cashmore Giovanni Fm Strippoli Source Type: research

Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure
ConclusionsThe use of milrinone compared with dobutamine in patients with ADHF-CS is associated with lower 30  day mortality and improved haemodynamics. These findings warrant further study in future randomized controlled trials.
Source: ESC Heart Failure - June 16, 2023 Category: Cardiology Authors: Eduard Rodenas ‐Alesina, Fernando Luis Scolari, Vicki N. Wang, Darshan H. Brahmbhatt, Vesna Mihajlovic, Nicole L. Fung, Madison Otsuki, Filio Billia, Christopher B. Overgaard, Adriana Luk Tags: Original Article Source Type: research

Incidence of Thromboembolic Complications Following Kidney Transplantation with Short and Extended Aspirin Prophylaxis: A Retrospective Single-Center Study
CONCLUSIONS Extended-duration aspirin use did not significantly reduce the incidence of VTE in the first 6 weeks following kidney transplantation. An association was identified between anti-human thymocyte immunoglobulin and VTE, which requires further assessment.PMID:37309097 | DOI:10.12659/AOT.939143
Source: Annals of Transplantation - June 13, 2023 Category: Transplant Surgery Authors: Angus H Pegler Katharine Hegerty Ryan P Gately Carmel M Hawley David W Johnson Yeoungjee Cho Dev K Jegatheesan Andrew B McCann Michelle E Harfield Nicole M Isbel Source Type: research

Risk of hospital admission or emergency department presentation due to diabetes complications: a retrospective cohort study in Tasmania, Australia
ConclusionsOur results demonstrated the high demand on hospital services due to diabetes complications (especially macrovascular complications) and highlighted the importance of preventing and properly managing microvascular complications. These findings will support future resource allocation to reduce the increasing burden of diabetes in Australia.PMID:37137728 | DOI:10.1071/AH22271
Source: Australian Health Review - May 3, 2023 Category: Hospital Management Authors: Ngan T T Dinh Barbara de Graaff Julie A Campbell Matthew D Jose John Burgess Timothy Saunder Alex Kitsos Petr Otahal Andrew J Palmer Source Type: research