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Specialty: Neurology
Condition: Bipolar

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Total 57 results found since Jan 2013.

Directional recordings of somatosensory evoked potentials from the sensory thalamus in chronic poststroke pain patients
CONCLUSIONS: SEP recordings from directional DBS leads offer additional information about the neurophysiological (re)organization of the sensory thalamus.SIGNIFICANCE: Directional recordings of thalamic SEPs bear the potential to assist clinical decision-making in DBS for pain.PMID:37156120 | DOI:10.1016/j.clinph.2023.03.359
Source: Clinical Neurophysiology - May 8, 2023 Category: Neurology Authors: Andreas Nowacki David Zhang Jonathan Wermelinger Pablo Abel Alvarez Abut Jan Rosner Claudio Pollo Kathleen Seidel Source Type: research

Effects of Cerebellar Transcranial Direct Current Stimulation in Patients with Stroke: a Systematic Review
ConclusionsctDCS appears to improve poststroke language and motor dysfunction (particularly gait). However, the evidence for these results was insufficient, and the quality of the relevant studies was low. ctDCS stimulation parameters and individual factors of participants may affect the therapeutic effect of ctDCS. Researchers need to take a more regulated approach in the future to conduct studies with large sample sizes. Overall, ctDCS remains a promising stroke intervention technique that could be used in the future.
Source: The Cerebellum - August 27, 2022 Category: Neurology Source Type: research

Phosphorylation of PI3K/Akt at Thr308, but not MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Exp Neurol. 2022 Feb 2:113996. doi: 10.1016/j.expneurol.2022.113996. Online ahead of print.ABSTRACTLithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its modulatory effect on GSK pathway. Therefore, we initially analyzed the dose-dependent effects of lithium on neurological deficits, infarct volume, brain edema and blood-brain barrier integrity, along with neuronal injury and survival in mice subjected to focal cerebral ischemia. Thereafter, we investigated the in...
Source: Experimental Neurology - February 5, 2022 Category: Neurology Authors: Nilay Ates Aysun Caglayan Zeynep Balcikanli Elif Sertel Mustafa Caglar Beker Pelin Dilsiz Ahmet Burak Caglayan S üleyman Celik Muhammed Furkan Dasdelen Berrak Caglayan T ürkan Yigitbasi Hanefi Ozbek Thorsten Roland Doeppner Dirk Matthias Hermann Ertugru Source Type: research

Functional seizures are associated with cerebrovascular disease and functional stroke is more common in patients with functional seizures than epileptic seizures
CONCLUSION: Our results confirm the initial observation of increased CVD in patients with FSe and further suggest that patients with FSe may be predisposed to developing another functional neurological disorder (FND) (i.e., functional stroke). We speculate that this may be due to shared risk factors and pathophysiological processes that are common to various manifestations of FND.PMID:35123242 | DOI:10.1016/j.yebeh.2022.108582
Source: Epilepsy and Behaviour - February 5, 2022 Category: Neurology Authors: Jonah Fox Slavina B Goleva Kevin F Haas Lea K Davis Source Type: research

Phosphorylation of PI3K/Akt at Thr308, but not MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
Exp Neurol. 2022 Feb 2:113996. doi: 10.1016/j.expneurol.2022.113996. Online ahead of print.ABSTRACTLithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its modulatory effect on GSK pathway. Therefore, we initially analyzed the dose-dependent effects of lithium on neurological deficits, infarct volume, brain edema and blood-brain barrier integrity, along with neuronal injury and survival in mice subjected to focal cerebral ischemia. Thereafter, we investigated the in...
Source: Experimental Neurology - February 5, 2022 Category: Neurology Authors: Nilay Ates Aysun Caglayan Zeynep Balcikanli Elif Sertel Mustafa Caglar Beker Pelin Dilsiz Ahmet Burak Caglayan S üleyman Celik Muhammed Furkan Dasdelen Berrak Caglayan T ürkan Yigitbasi Hanefi Ozbek Thorsten Roland Doeppner Dirk Matthias Hermann Ertugru Source Type: research

Effects of Galvanic Vestibular Stimulation on Visual Verticality and Standing Posture Differ Based on the Polarity of the Stimulation and Hemispheric Lesion Side in Patients With Stroke
Conclusions: These findings demonstrate that the effects of GVS on the SVV and standing posture differ depending on the polarity of GVS and the hemispheric lesion side. Patients with a right hemisphere lesion have difficulty maintaining their preferred standing posture under visual verticality modulation evoked by GVS. The application of GVS may clarify whether the vestibular system has neural redundancy after stroke to suppress any effects of the stimulation, including modulation of the visual verticality, on balance.
Source: Frontiers in Neurology - November 11, 2021 Category: Neurology Source Type: research

Immuno-histological detection of resistant columnar units and vulnerable networks in the rat retina after asphyxia-induced transient cardiac arrest
CONCLUSIONS: Regardless of the many defects, the surviving neuronal structures seemed to be able to maintain retinal functionality, which can be additionally improved by regenerative processes true to the "use it or lose it" dogma.PMID:34334436 | DOI:10.3233/RNN-211174
Source: Restorative Neurology and Neuroscience - August 2, 2021 Category: Neurology Authors: Gerburg Keilhoff Maximilian Titze Uwe Ebmeyer Source Type: research