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Condition: Coronary Heart Disease
Nutrition: Calcium

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Total 85 results found since Jan 2013.

Coronary artery disease grading by cardiac CT for predicting outcome in patients with stable angina
CONCLUSION: In patients referred for invasive angiography, a history of CHD was the strongest predictor of MACE. In patients without history of CHD, a coronary calcium score yielded at least equal risk stratification vs. more complex CHD grading.PMID:37541910 | DOI:10.1016/j.jcct.2023.07.004
Source: Atherosclerosis - August 4, 2023 Category: Cardiology Authors: Christian U Oeing Matthew B Matheson Mohammad R Ostovaneh Carlos E Rochitte Marcus Y Chen Burkert Pieske Klaus F Kofoed Joanne D Schuijf Hiroyuki Niinuma Marc Dewey Marcelo F di Carli Christopher Cox Jo ão A C Lima Armin Arbab-Zadeh Source Type: research

First-line diuretics versus other classes of antihypertensive drugs for hypertension
CONCLUSIONS: When used as first-line agents for the treatment of hypertension, thiazides and thiazide-like drugs likely do not change total mortality and likely decrease some morbidity outcomes such as cardiovascular events and withdrawals due to adverse effects, when compared to beta-blockers, calcium channel blockers, ACE inhibitors, and alpha-blockers.PMID:37439548 | DOI:10.1002/14651858.CD008161.pub3
Source: Cochrane Database of Systematic Reviews - July 13, 2023 Category: General Medicine Authors: Marcia Reinhart Lorri Puil Douglas M Salzwedel James M Wright Source Type: research

Relationship Between Thoracic Aortic Calcification And Coronary Artery Calcium Measured On Chest CT Scans
Introduction: Cerebrovascular accidents (CVA) remain a leading cause of mortality and morbidity worldwide. Identifying appropriate risk markers may allow detection of patients at high risk for stroke who would benefit from early initiation of preventative measures. Utilizing atherosclerotic burden of multiple vascular beds may allow for improved cardiovascular risk assessment. Coronary artery calcium (CAC) is a well-established, excellent predictor of coronary heart disease, but its association with stroke is modest.
Source: Journal of Cardiovascular Computed Tomography - July 1, 2023 Category: Radiology Authors: A. Zeitjian, B. Noor, V. Manubolu, A. Kinninger, M. Budoff Source Type: research

Subclinical Vascular Composites Predict Clinical Cardiovascular Disease, Stroke, and Dementia: The Multi-Ethnic Study of Atherosclerosis (MESA)
CONCLUSIONS: Subclinical vascular composites of arteriosclerosis and atherosclerosis may be useful biomarkers to inform the vascular pathways contributing to events of CVD, CHD, stroke, and dementia.PMID:37205504 | PMC:PMC10187443 | DOI:10.1101/2023.05.01.23289364
Source: Atherosclerosis - May 19, 2023 Category: Cardiology Authors: Timothy M Hughes Jordan Tanley Haiying Chen Christopher L Schaich Joseph Yeboah Mark A Espeland Joao A C Lima Bharath Ambale-Venkatesh Erin D Michos Jingzhong Ding Kathleen Hayden Ramon Casanova Suzanne Craft Stephen R Rapp Jos é A Luchsinger Annette L F Source Type: research

Protective effect of antihypertensive drugs on the risk of Parkinson ’s disease lacks causal evidence from mendelian randomization
Conclusion: Our data suggest that BP and commonly prescribed AHMs may not have a prominent role in PD etiology.
Source: Frontiers in Pharmacology - February 23, 2023 Category: Drugs & Pharmacology Source Type: research

Mendelian randomization study of the effect of coronary artery calcification on atherosclerotic cardiovascular diseases
In this study, we used Mendelian randomization (MR) to systematically investigate the causal role of CAC across a broad range of atherosclerotic cardiovascular diseases including coronary heart disease, angina, MI, ischemic heart disease, stroke, and peripheral vascular disease. Publicly available data from the UK biobank and other data sources were used. Using the two-sample Mendelian randomization (MR) approach, we applied 3 MR models including the inverse variance weighted, the weighted-median, and the weighted-mode methods. Eight SNPs associated with CAC were selected as instrumental variables. We observed causal evide...
Source: Atherosclerosis - September 1, 2022 Category: Cardiology Authors: Wichanon Sae-Jie Tarinee Tangcharoen Prin Vathesatogkit Wichai Aekplakorn Pimphen Charoen Source Type: research

Association of polygenic risk scores with incident atherosclerotic cardiovascular disease events among individuals with coronary artery calcium score of zero: The multi-ethnic study of atherosclerosis
CONCLUSIONS: Among individuals with CAC = 0, the ASCVD PRS was associated with incident ASCVD events. This appears to be driven by genetic variants related to stroke but not CHD, and particularly among women and non-Whites. ASCVD event rates remained below the threshold recommended for consideration for initiation of statin therapy even in the high PRS groups.PMID:35952728 | DOI:10.1016/j.pcad.2022.08.003
Source: Atherosclerosis - August 11, 2022 Category: Cardiology Authors: Mahmoud Al Rifai Jie Yao Xiuqing Guo Wendy S Post Shaista Malik Roger S Blumenthal Christie M Ballantyne Matthew Budoff Kent D Taylor Henry J Lin Stephen S Rich Catherine Hajek Philip Greenland Jerome I Rotter Salim S Virani Source Type: research

Polycystic ovary syndrome: a "risk-enhancing" factor for cardiovascular disease
Fertil Steril. 2022 May;117(5):924-935. doi: 10.1016/j.fertnstert.2022.03.009.ABSTRACTPolycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic ovarian morphology. Polycystic ovary syndrome, particularly the hyperandrogenism phenotype, is associated with several cardiometabolic abnormalities, including obesity, dyslipidemia, elevated blood pressure, and prediabetes or type 2 diabetes. Many, but not all, studies have suggested that PCOS is associated with increased risk of cardiovascular disease (CVD), includi...
Source: Atherosclerosis - May 5, 2022 Category: Cardiology Authors: Carolyn Guan Salman Zahid Anum S Minhas Pamela Ouyang Arthur Vaught Valerie L Baker Erin D Michos Source Type: research

The New Era of Retinal Imaging in Hypertensive Patients
Structural and functional alterations in the microcirculation by systemic hypertension can cause significant organ damage at the eye, heart, brain, and kidneys. As the retina is the only tissue in the body that allows direct imaging of small vessels, the relationship of hypertensive retinopathy signs with development of disease states in other organs have been extensively studied; large-scale epidemiological studies using fundus photography and advanced semi-automated analysis software have reported the association of retinopathy signs with hypertensive end-organ damage includes the following: stroke, dementia, and coronar...
Source: Asia-Pacific Journal of Ophthalmology - March 1, 2022 Category: Opthalmology Tags: Review Article Source Type: research

Lifetime Cardiovascular Disease Risk by Coronary Artery Calcium Score in Individuals With and Without Diabetes: An Analysis From the Multi-Ethnic Study of Atherosclerosis
CONCLUSIONS: Patients with diabetes carry a spectrum of CVD risk. CAC scoring may improve decisions for preventive interventions for patients with diabetes by better delineating lifetime CVD risk.PMID:35168253 | DOI:10.2337/dc21-1607
Source: Atherosclerosis - February 15, 2022 Category: Cardiology Authors: Bart S Ferket M G Myriam Hunink Umesh Masharani Wendy Max Joseph Yeboah Gregory L Burke Kirsten E Fleischmann Source Type: research

Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
Clin Exp Hypertens. 2022 Jan 3:1-9. doi: 10.1080/10641963.2021.2022688. Online ahead of print.ABSTRACTIn 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the management of hypertension. To evaluate adherence to the guidelines, this retrospective study assessed the real-world status of antihypertensive drug prescribing for Chinese patients with hypertension, classified by comorbidity: coro...
Source: Clinical and Experimental Hypertension - January 3, 2022 Category: Cardiology Authors: Renren Yang Jia Tang Yunping Zhuo Ming Kuang Hongying Liu Source Type: research