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Condition: Dementia
Countries: Japan Health

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Total 67 results found since Jan 2013.

Hobby engagement and risk of disabling dementia
CONCLUSIONS: Hobby engagement in both mid-life and late-life was associated with a lower risk of disabling dementia without a history of stroke.PMID:35569953 | DOI:10.2188/jea.JE20210489
Source: Journal of Epidemiology - May 15, 2022 Category: Epidemiology Authors: Takumi Matsumura Isao Muraki Ai Ikeda Kazumasa Yamagishi Kokoro Shirai Nobufumi Yasuda Norie Sawada Manami Inoue Hiroyasu Iso Eric J Brunner Shoichiro Tsugane Source Type: research

Isotemporal Substitution of Sedentary Behavior with Moderate- to Vigorous- Physical Activity Is Associated with Lower Risk of Disability: A Prospective Longitudinal Cohort Study
CONCLUSIONS: Replacing SB with MVPA was associated with a lower risk of disability. These findings are helpful for establishing disability prevention strategies.IMPACT: These results suggest that feasible changes in daily behavior, such as replacing 10 minutes of SB with MVPA daily, might have a protective effect on disability incidence. Clarifying these associations is useful for developing disability prevention strategies and may help reduce the incidence of disability in community-dwelling older adults.PMID:35079837 | DOI:10.1093/ptj/pzac002
Source: Physical Therapy - January 26, 2022 Category: Physiotherapy Authors: Ippei Chiba Sangyoon Lee Seongryu Bae Keitaro Makino Yohei Shinkai Osamu Katayama Kenji Harada Yukari Yamashiro Naoto Takayanagi Hiroyuki Shimada Source Type: research

Cardiovascular disease, a major global burden: Epidemiology of stroke and ischemic heart disease in Japan
Glob Health Med. 2021 Dec 31;3(6):358-364. doi: 10.35772/ghm.2020.01113.ABSTRACTJapan ranks the highest globally, in terms of longevity. The average life expectancy was 81.4 years for men and 87.5 years for women in 2019. Such success in health is attributable to the substantial reduction in age-standardized mortality from cardiovascular diseases, especially stroke (136 per 105 in 1980 and 24 per 105 in 2015), when stroke mortality was the highest in the world between the 1960s and the 1990s. On the other hand, ischemic heart disease mortality was the lowest in the world between the 1960s and the 1980s and has continued to...
Source: Atherosclerosis - January 17, 2022 Category: Cardiology Authors: Hiroyasu Iso Source Type: research

Association Between Oral Anticoagulants and Stroke Severity at Onset in Elderly Patients with Cardioembolic Stroke Due to Non-Valvular Atrial Fibrillation
The prevention of cardioembolic stroke is an important public health priority in Japan due to its high prevalence in elderly individuals. Compared to their younger counterparts, elderly patients with cardioembolic stroke are more likely to have multiple comorbidities, a higher risk of serious complications, such as pneumonia and heart failure, and cognitive impairments (e.g., dementia or delirium), which may adversely affect their ability to participate in active rehabilitation. These factors negatively affect clinical outcomes, and many elderly stroke survivors require long-term care despite the early implementation of intensive therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2021 Category: Neurology Authors: Ichiro Deguchi, Takashi Osada, Shinichi Takahashi Source Type: research

Genes, Vol. 12, Pages 1955: Novel In-Frame Deletion in HTRA1 Gene, Responsible for Stroke at a Young Age and Dementia & mdash;A Case Study
We present the case of a Lithuanian male patient who had a stroke at the age of 36, experienced several transient ischemic attacks, and developed an early onset, progressing dementia. These clinical symptoms were associated with extensive leukoencephalopathy, lacunar infarcts, and microbleeds based on brain magnetic resonance imaging (MRI). A novel heterozygous in-frame HTRA1 gene deletion (NM_002775.5:c.533_535del; NP_002766.1:p.(Lys178del)) was identified by next generation sequencing. The variant was consistent with the patient’s phenotype, which could not be explained by alternative causes, appeared highl...
Source: Genes - December 7, 2021 Category: Genetics & Stem Cells Authors: Julija Grigait ė Kamil ė Šiaurytė Egl ė Audronytė Egl ė Preikšaitienė Birut ė Burnytė Erinija Pranckevi čienė Aleksandra Ekkert Algirdas Utkus Dalius Jatu žis Tags: Article Source Type: research

Incidence and Risk Factors of Future Need for Long-Term Care Insurance in Japanese Elderly Patients With Left Ventricular Systolic Dysfunction
CONCLUSIONS: In elderly patients with LV systolic dysfunction, the incidence of LTCI requirement was more common than that for community-dwelling people; its risk factors did not include LVEF, but included many other non-cardiac comorbidities and therapies, suggesting the need for interdisciplinary cooperation to prevent disabilities.PMID:34789610 | DOI:10.1253/circj.CJ-21-0580
Source: Circulation Journal - November 18, 2021 Category: Cardiology Authors: Shinya Fujiki Takeshi Kashimura Yuji Okura Kunio Kodera Hiroshi Watanabe Komei Tanaka Shogo Bannai Taturo Hatano Takahiro Tanaka Nobutaka Kitamura Tohru Minamino Takayuki Inomata Source Type: research

Analyzing Cost-Effectiveness of Allocating Neurointerventionist for Drive and Retrieve System for Patients with Acute Ischemic Stroke
The cost of stroke treatment accounts for approximately 6% of Japan's national medical expenditure,1 and stroke is the second most common condition, after dementia, that results in a requirement for long-term care. Thus, stroke has a significant impact on society.2 Cerebral infarction accounts for 60% or more of stroke cases.3 Systematic provision of highly equitable and efficient treatment for cerebral infarction is an important policy issue, such as the enactment of the Stroke and Cardiovascular Disease Control Act in December 2018 in Japan, as part of an effort to enhance provision of treatment for cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2021 Category: Neurology Authors: Yasuhiro Morii, Toshiya Osanai, Kensuke Fujiwara, Takumi Tanikawa, Kiyohiro Houkin, Songzi Gu, Katsuhiko Ogasawara Source Type: research