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Condition: Autoimmune Disease
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Total 584 results found since Jan 2013.
Acute Low Dose Naltrexone Increases β-Endorphin and Promotes Neuronal Recovery Following Hypoxia-Ischemic Stroke in Type-2 Diabetic Mice
Neurochem Res. 2023 May 11. doi: 10.1007/s11064-023-03938-4. Online ahead of print.ABSTRACTDiabetic patients experience significant mortality and poor recovery following ischemic stroke. Our clinical and basic science studies demonstrate an overall immune suppression in the periphery of diabetic stroke patients, as well as within the central nervous system (CNS) of type-2 diabetic mice following hypoxia-ischemia (HI). Low doses of naltrexone (LDN) improved clinical outcomes in many autoimmune diseases by acting on opioid receptors to release β-endorphin which in turn balances inflammatory cytokines and modulates the opioi...
Source: Neurochemical Research - May 11, 2023 Category: Neuroscience Authors: Rashmi Kumari Zainab Y Kareem Patricia J McLaughlin Source Type: research
Outcomes of hemorrhagic stroke in patients with autoimmune rheumatic diseases: An analysis of the US Nationwide Inpatient Sample
ConclusionsAmong patients admitted to US hospitals for hemorrhagic stroke, patients with RA had decreased risk for in-hospital mortality and prolonged LOS.
Source: International Journal of Rheumatic Diseases - September 20, 2023 Category: Rheumatology Authors: Mao ‐Yu Chen,
Pin‐Yuan Chen,
Chen‐Nen Chang,
Bo‐An Chen,
Wen‐Chun Deng,
Jiun‐Lin Yan Tags: ORIGINAL ARTICLE Source Type: research
Ischemic stroke as a presenting feature of Wegener's granulomatosis.
We describe a 51-old-male who presented with complaints of slurred speech and left-sided weakness, along with bilateral pulmonary nodules on initial chest x-ray, which were associated with pulmonary symptoms in the past. A repeated computed tomography (CT) scan showed ischemia in the distribution of the right-middle cerebral artery. An open lung biopsy showed vasculitis with necrosis of a vessel wall, with a multinucleated giant cell, confirming the diagnosis of WG. The patient was successfully treated with cyclophosphamide and oral prednisone and he has continued in remission for one year.
PMID: 24266130 [PubMed - in process]
Source: Connecticut Medicine - October 1, 2013 Category: Journals (General) Authors: Jethava A, Ali S Tags: Conn Med Source Type: research
Moyamoya Disease Associated with Asymptomatic Mosaic Turner Syndrome: A Rare Cause of Hemorrhagic Stroke
We present the first reported case of an adult patient with previously unrecognized mosaic Turner syndrome with acute subarachnoid and intracerebral hemorrhage as the initial manifestation of moyamoya syndrome. A 52-year-old woman was admitted with a subarachnoid hemorrhage with associated flame-shaped intracerebral hemorrhage in the left frontal lobe. Physical examination revealed short stature, pectus excavatum, small fingers, micrognathia, and mild facial dysmorphism. Cerebral angiography showed features consistent with bilateral moyamoya disease, aberrant intrathoracic vessels, and an unruptured 4-mm right superior hyp...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Sunil Manjila, Benjamin R. Miller, Anitha Rao-Frisch, Balint Otvos, Anna Mitchell, Nicholas C. Bambakidis, Michael A. De Georgia Tags: Case Reports Source Type: research
Stroke risk rose in autoimmune disease patients after herpes zoster
Stroke risk was 50% higher in the month after patients with autoimmune diseases developed herpes zoster, compared with the next 2-6 years, according to Dr. Leonard H. Calabrese.
“These data provide urgency for developing strategies to reduce the risk of varicella zoster virus in vulnerable...
Source: Skin and Allergy News - November 8, 2015 Category: Dermatology Source Type: news
Association of hepatitis B virus infection with decreased ischemic stroke
ConclusionHBV was correlated with a reduced risk of AIS development. Although a decrease in AIS risk was noted in the patients with HBV, preventing the development of AIS in this population warrants further attention.
Source: Acta Neurologica Scandinavica - December 21, 2015 Category: Neurology Authors: C.‐H. Tseng, C.‐H. Muo, C.‐Y. Hsu, C.‐H. Kao Tags: Original Article Source Type: research
Ultrasound-guided corticosteroid injections for adhesive capsulitis more effective than placebo
Commentary on: Prestgaard T, Wormgoor ME, Haugen S, et al.. Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study. Pain 2015;156:1683–91. Context Adhesive capsulitis (frozen shoulder or painful stiff shoulder) is relatively common. It is idiopathic: known associated factors include trauma, diabetes, prolonged immobilisation, age, stroke and autoimmune disease. While self-limited, pain and decreased range of motion can last up to 2–3 years. Therefore, there is practical value in therapeutic in...
Source: Evidence-Based Medicine - March 21, 2016 Category: Internal Medicine Authors: Lebrun, C. M. Tags: Rehabilitation medicine, Immunology (including allergy), Pain (neurology), Stroke, Radiology, Degenerative joint disease, Musculoskeletal syndromes, Osteoarthritis, Sports and exercise medicine, Clinical diagnostic tests, Radiology (diagnostics), Screenin Source Type: research
Case presentation: the dancing man from sierra leone
Discussion
Making this diagnosis is challenging, as brain imaging often shows non specific changes and blood results are usually normal. CSF may reveal raised proteins and WBCs. A high index of suspicion is required to arrange a brain biopsy as this confirms the diagnosis.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Al-Rifai, M. S., Salek-Haddadi, A. Tags: Immunology (including allergy), Neuroimaging, Stroke, Radiology, Drugs: musculoskeletal and joint diseases, Vascularitis, Surgical diagnostic tests ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research
A Recurrent Case of Ischemic Stroke Caused by Vasospasm due to Giant Cell Arteritis
A 73-year-old man was admitted with sudden right upper-limb weakness. He had a temporal headache on the left side and had a 4-month history of fever. Meandering of the left temporal artery (TA) with induration and high inflammatory responses (white blood cell count 22,500 per microliter, C-reactive protein 35.0 mg/dL, and elevated sedimentation rate [ESR] 80 mm/h) were observed. Glycometabolism and lipid metabolism were normal, and autoimmune antibodies were negative. Cultivation tests revealed no bacteria in either blood culture or cerebrospinal fluid.
Source: Journal of Stroke and Cerebrovascular Diseases - August 23, 2017 Category: Neurology Authors: Reina Kawamura, Atsushi Mizuma, Maiko Kouchi, Eiichiro Nagata, Wakoh Takahashi, Shunya Takizawa Tags: Case Studies Source Type: research
Autoimmune limbic encephalitis in association with acute stroke
A 60-year-old woman with no known medical history presented with acute-onset altered mental status and aphasia. She was in her usual state of health until the time of presentation. She was found to have left middle and posterior cerebral artery (MCA and PCA) acute ischemic strokes and subsequently developed refractory status epilepticus. CT angiography showed moderate stenosis of the proximal left internal carotid artery (ICA), occlusion of the right ICA at its origin, and near-complete occlusion of the left vertebral artery (figure). Strokes were attributed to large-vessel atherosclerotic disease in the setting of multipl...
Source: Neurology Clinical Practice - August 13, 2018 Category: Neurology Authors: Kaas, B., Zeiler, S. R., Bahouth, M. N., Llinas, R. H., Probasco, J. C. Tags: All Immunology, All Cerebrovascular disease/Stroke Case Source Type: research
Getting the Right Care for Painful Autoimmune Conditions
A corticosteroid can quickly relieve symptoms of both polymyalgia rheumatica and temporal arteritis. But a delay could cause vision loss, a stroke or even death.
Source: NYT Health - August 19, 2019 Category: Consumer Health News Authors: Jane E. Brody Tags: Stroke Steroids Autoimmune Diseases Immune System Source Type: news
Risk factors and characteristics of ischemic stroke in patients with immune thrombocytopenia: A retrospective cohort study
Immune thrombocytopenia (ITP), also known as idiopathic thrombocytopenic purpura, is an autoimmune disease characterized by a platelet count of
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2022 Category: Neurology Authors: Xi Rong, Lidan Jiang, Meijie Qu, Shaonan Yang, Kun Wang, Liwei Jiang Source Type: research
Nasu-Hakola Disease With Stroke-like Attack: A Case Report
Alzheimer Dis Assoc Disord. 2023 Feb 20. doi: 10.1097/WAD.0000000000000547. Online ahead of print.ABSTRACTHomozygous mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) gene are known to cause Nasu-Hakola disease, which is a rare cause of progressive presenile dementia. A 36-year-old woman presented with repetitive seizures, a 5-year history of progressive behavioral and cognitive changes, and an affected sibling. Magnetic resonance imaging of the brain revealed an ischemic lesion in the left medial temporal lobe. Extensive evaluation of juvenile stroke revealed that viral and autoimmune encephalitide...
Source: Alzheimer Disease and Associated Disorders - February 23, 2023 Category: Psychiatry Authors: Azra Rashid Nezhad Nahid Olfati Ali Shoeibi Fariborz Rezaei Talab Mohsen Soltani Sabi Source Type: research
