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Specialty: Research
Condition: Bleeding

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Total 130 results found since Jan 2013.

Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry.
CONCLUSION: Based on the data from this registry, ablation of PVCs is a safe and efficient procedure with an excellent outcome and improved symptoms after 12 months. PMID: 27484499 [PubMed - as supplied by publisher]
Source: Clin Med Res - August 1, 2016 Category: Research Authors: Fichtner S, Senges J, Hochadel M, Tilz R, Willems S, Eckardt L, Deneke T, Lewalter T, Dorwarth U, Reithmann C, Brachmann J, Steinbeck G, Kääb S, German Ablation Registry Tags: Clin Res Cardiol Source Type: research

Id: 24: benefits and risks of warfarin with and without aspirin in patients with coronary artery disease or cerebrovascular accident: a meta-analysis of randomized controlled trials
Conclusions Use of intermediate intensity warfarin with aspirin reduced the risk of stroke at the price of increased bleeding. Most anticoagulation increased the risk of major bleeding with no effect on mortality. Studies with oral anticoagulants with aspirin for secondary prevention should be considered.
Source: Journal of Investigative Medicine - March 21, 2016 Category: Research Authors: Deshpande, A., Patel, K., Rothberg, M., Pasupuleti, V., Alreja, G., Katzan, I. Tags: Epidemiology/Health Care Outcomes/Quality Improvement/Bioinformatics Source Type: research

An early evaluation of bleeding-related hospital readmissions among hospitalized patients with nonvalvular atrial fibrillation treated with direct oral anticoagulants.
CONCLUSIONS: NVAF patients using different DOACs had different characteristics, including stroke and bleeding risks. Use of rivaroxaban, compared to apixaban was associated with significantly greater risk of bleeding-related readmissions across two database claims analyses. PMID: 26652179 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - February 18, 2016 Category: Research Tags: Curr Med Res Opin Source Type: research

Clinical Relevance of Anticoagulation and Dual Antiplatelet Therapy to the Outcomes of Patients With Atrial Fibrillation and Recent Percutaneous Coronary Intervention With Stent.
CONCLUSIONS: TT, DT and DAPT displayed similar efficacy and safety. Although the superiority of OAC vs. DAPT for stroke prevention in AF patients has been demonstrated by previous randomized trials, a smaller frequency of high thromboembolic risks' features in DAPT group of the present study may have prevented the observation of a higher incidence of ischemic stroke in this group. PMID: 26767085 [PubMed]
Source: Clin Med Res - January 18, 2016 Category: Research Authors: De Vecchis R, Cantatrione C, Mazzei D Tags: J Clin Med Res Source Type: research

Real-World Analysis of more than 44,000 Patients Reinforces Safety and Effectiveness of Pradaxa® in Routine Clinical Care
• New data show Pradaxa® reduced stroke risk and major bleeding compared to warfarin in patients with non-valvular atrial fibrillation1 • Pradaxa® was associated with 28% and 26% reductions in stroke risk and major bleeding events compared to warfarin, respectively1
Source: Boehringer Ingelheim Corporate News - November 9, 2015 Category: Research Source Type: news

Safety and Efficacy Analyses of Angioplasty and Stenting for Severe Intracranial Arterial Stenosis: A Single-Center Retrospective Study in China.
CONCLUSIONS A suitable PTAS procedure is safe for patients with severe ICAS, and no significant differences in incidence of recurrent stroke or death were found between PTAS and aggressive medication treatment. PMID: 26517946 [PubMed - as supplied by publisher]
Source: Medical Science Monitor - November 2, 2015 Category: Research Tags: Med Sci Monit Source Type: research

Novel Oral P2Y12 Inhibitor Prasugrel vs. Clopidogrel in Patients with Acute Coronary Syndrome: Evidence Based on 6 Studies.
CONCLUSIONS Prasugrel has similar effects as clopidogrel in terms of all causes of death, MI, and stroke in ACS patients. For the patients who underwent PCI, prasugrel contributes to lower risk of stent thrombosis. However, prasugrel is associated with significantly higher risk of bleeding. For the patients with active pathological bleeding or a history of stroke and/or TIA, prasugrel should not be recommended. PMID: 25893318 [PubMed - in process]
Source: Medical Science Monitor - April 22, 2015 Category: Research Tags: Med Sci Monit Source Type: research

'Enzyme Whisperer' Named a Finalist for First-Ever National Blavatnik Award for Young Scientists - 5/21/14
Johns Hopkins researchers say they have developed a technique that can predict — with 95 percent accuracy — which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain.
Source: Johns Hopkins Medicine News - May 21, 2014 Category: Research Source Type: news

Predicting Which Stroke Patients Will Be Helped — or Harmed — by Clot-Busting Treatment - 5/20/14
Johns Hopkins researchers say they have developed a technique that can predict — with 95 percent accuracy — which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain.
Source: Johns Hopkins Medicine News - May 20, 2014 Category: Research Source Type: news

Edoxaban Effective in Preventing Stroke, Reducing Bleeding and Cardiovascular Death in Patients With Atrial Fibrillation
New study demonstrates that high- and low-dose edoxaban were at least as effective in preventing stroke or systemic embolism (blood clot), while significantly reducing bleeding and cardiovascular death, compared to warfarin.
Source: BWH for Journalists - November 19, 2013 Category: Research Source Type: news