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Condition: Locked-In Syndrome

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Total 53 results found since Jan 2013.

Comparison of the Checkerboard P300 Speller vs. the Row-Column Speller in Normal Elderly and an Aphasic Stroke Population (S21.006)
CONCLUSION: Our study demonstrates that stroke patients with Broca’s aphasia can use a P300 visual speller to communicate. Our results also indicate that in the elderly population, CBP is a superior paradigm compared to RCP. Disclosure: Dr. Shih has received research support from Eisai Inc., and Visualase Inc. Dr. Townsend has nothing to disclose. Dr. Krusienski has nothing to disclose. Dr. Shih has nothing to disclose. Dr. Shih has nothing to disclose. Dr. Heggeli has nothing to disclose. Dr. Paris has nothing to disclose. Dr. Meschia has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shih, J., Townsend, G., Krusienski, D., Shih, K., Shih, R., Heggeli, K., Paris, T., Meschia, J. Tags: Neuro-rehabilitation and Neural Repair Source Type: research

Effect of Exercise on Physical Recovery of People with Locked-In Syndrome after Stroke: What Do We Know from the Current Evidence? A Systematic Review
Conclusion: Studies indicate a positive trend of effect of exercise for physical recovery of people with LIS after stroke including the improvement of muscle strength, tone, walking ability, and activity in daily living. Mixed physical exercises were used. The effects were not significant. No adverse event has been reported. The quality of the existing evidence is relatively low since the papers were either case series or case studies. Further studies are needed on exercise types and dosages for better prescriptions for people with LIS after stroke. This may help to extend their lives with better control of the complicatio...
Source: Cerebrovascular Diseases Extra - July 13, 2018 Category: Neurology Source Type: research

Assistive technology offers a brighter future for locked-in syndrome
A team of researchers from Montreal has found that stroke patients living with Locked-In Syndrome (LIS) who cannot move, swallow or even breathe on their own, can regain a remarkable level of independence with technological help. The team's findings, presented at the Canadian Stroke Congress, stem from a 20-year study that followed the rehabilitation of 25 LIS patients, people who are aware and awake but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles...
Source: Health News from Medical News Today - October 21, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Profuse Unilateral Hyperhidrosis Induced by Urinary Retention in a Stroke Patient
Conclusions: This case provides the first description of unilateral hyperhidrosis as a manifestation of urinary retention in a stroke patient. It is important for clinicians to recognize this condition so that appropriate management can be implemented in time to prevent potential detrusor injury and renal impairment caused by bladder overdistension.
Source: The Neurologist - February 1, 2015 Category: Neurology Tags: Case Report/Case Series Source Type: research

The locked-in syndrome: posterior stroke in the ED
We present this report and brief review as it is unusual to watch locked-in syndrome evolve in the ED. Providers should be aware of the presenting symptoms and the differential diagnosis for bulbar muscle weakness as well as the management of posterior stroke.
Source: The American Journal of Emergency Medicine - May 22, 2013 Category: Emergency Medicine Authors: Corey Goldberg, Stephen Topp, Christopher Hopkins Tags: Case Reports Source Type: research

Locked-In Syndrome
Information sheet on locked-in syndrome compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research

"Reverse Locked-in Syndrome": A rare presentation after endovascular recanalization of top-of-the-basilar artery occlusion (P4.302)
CONCLUSION: Complete opthalmoplegia, bilateral ptosis, and arreactive mydriasis without appendicular motor dysfunction, a "reverse locked-in" state, is a rare presentation after ischemic stroke involving the paramedian midbrain tegmentum. This syndrome is the opposite of locked-in syndrome, which is cause by ventral pontine infarction. Timely endovascular thrombectomy, even when a patient presents in coma, may offer dramatic recovery with good functional outcome.Disclosure: Dr. Raibagkar has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Kaplan has nothing to disclose. Dr. Chavali has nothing to disclose. Dr. Ni...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Raibagkar, P., Kim, J., Kaplan, T., Chavali, R., Nitka, M., Chou, S., Edlow, B. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

Brain-Machine Interfaces (BMI) in paralysis
Publication date: Available online 8 January 2015 Source:Annals of Physical and Rehabilitation Medicine Author(s): U. Chaudhary , N. Birbaumer , M.R. Curado Introduction Brain-machine interfaces (BMIs) use brain activity to control external devices, facilitating paralyzed patients to interact with the environment. In this review, we focus on the current advances of non-invasive BMIs for communication in patients with amyotrophic lateral sclerosis (ALS) and for restoration of motor impairment after severe stroke. BMI for ALS patients BMI represents a promising strategy to establish communication with paralyzed ALS patien...
Source: Annals of Physical and Rehabilitation Medicine - January 9, 2015 Category: Rehabilitation Source Type: research

Brain-Machine Interface (BMI) in paralysis
Publication date: Available online 8 January 2015 Source:Annals of Physical and Rehabilitation Medicine Author(s): U. Chaudhary , N. Birbaumer , M.R. Curado Introduction Brain-machine interfaces (BMIs) use brain activity to control external devices, facilitating paralyzed patients to interact with the environment. In this review, we focus on the current advances of non-invasive BMIs for communication in patients with amyotrophic lateral sclerosis (ALS) and for restoration of motor impairment after severe stroke. BMI for ALS patients BMI represents a promising strategy to establish communication with paralyzed ALS patien...
Source: Annals of Physical and Rehabilitation Medicine - January 24, 2015 Category: Rehabilitation Source Type: research

'Computer helps patients with severe MND communicate'
Conclusion It's hard to imagine the situation of being alert, aware of what's happening around you, but unable to move, respond or communicate with the outside world. So it is comforting, then, to hear that people with complete locked-in syndrome may be able to communicate – and may be relatively content with their situation. However, it's important to remember the limitations of this study. It's very small. Only four people took part, and full results are available for only three of them. The results may only apply to people with this very specific type of neurodegenerative disease, not to people with other types of pa...
Source: NHS News Feed - February 1, 2017 Category: Consumer Health News Tags: Neurology Source Type: news

'Breakthrough in communication for patients with severe MND', study claims
Conclusion It's hard to imagine the situation of being alert, aware of what's happening around you, but unable to move, respond or communicate with the outside world. So it is comforting, then, to hear that people with complete locked-in syndrome may be able to communicate – and may be relatively content with their situation. However, it's important to remember the limitations of this study. It's very small. Only four people took part, and full results are available for only three of them. The results may only apply to people with this very specific type of neurodegenerative disease, not to people with other types of pa...
Source: NHS News Feed - February 1, 2017 Category: Consumer Health News Tags: Neurology Source Type: news

Basilar artery thrombosis during sexual intercourse
We report a young woman with a life-threatening basilar artery thrombosis during sexual intercourse, with a resulting locked-in syndrome. The positive high intensity transient signals (HITS) diagnosis showed a right-to-left shunt and is in line with paradoxic embolism. The molecular genetics revealed a homozygosity 4G/4G in the region PAI1, -675 (promoter polymorphism) as a risk factor for ischemic stroke. Sexual intercourse is a possible, albeit unusual stroke cause, especially in young people.
Source: Journal of Clinical Neuroscience - January 23, 2020 Category: Neuroscience Source Type: research

The clinical and cognitive spectrum of locked-in syndrome: 1-year follow-up of 100 patients
AbstractIn patients with locked-in syndrome (LIS), it is not known exactly to what extent cognitive functions are preserved and it is not known exactly how much it has improved. We aimed to examine the clinical and cognitive features of LIS 1 year after stroke. One hundred patients with locked-in syndrome (LIS) were recruited between January 2008 and May 2019 among 8200 patients with ischemic stroke. Patients were classified into two groups as single pontine infarcts (n = 72), and pontine plus multiple ischemic lesions (PMIL) (n = 28). Since the patients had limited motor and verbal response, the cognitive status o...
Source: Acta Neurologica Belgica - May 13, 2021 Category: Neurology Source Type: research

Unlocking a brighter future for locked-in syndrome
(Heart and Stroke Foundation of Canada) A team of researchers from Montreal has found that stroke patients living with Locked-In Syndrome who cannot move, swallow or even breathe on their own, can regain a remarkable level of independence with technological help.
Source: EurekAlert! - Medicine and Health - October 17, 2013 Category: Global & Universal Source Type: news

Learning from brain control: clinical application of brain–computer interfaces
In conclusion, clinical application of brain machine interfaces in well-defined and circumscribed neurological disorders have demonstrated surprisingly positive effects. The application of BCIs to psychiatric and clinical–psychological problems, however, at present did not result in substantial improvement of complex behavioral disorders.
Source: e-Neuroforum - October 6, 2015 Category: Neuroscience Source Type: research