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Long-term outcomes of mechanical versus biological valve prosthesis in native mitral valve infective endocarditis
Conclusion. The use of mechanical mitral valve prosthesis is associated with lower long-term mortality compared to the biological prosthesis in non-elder native mitral valve infective endocarditis patients. The routine choice of biological mitral valve prostheses for this patient group is not supported by the results.PMID:35652503 | DOI:10.1080/14017431.2022.2079712
Source: Scandinavian Cardiovascular Journal - June 2, 2022 Category: Cardiology Authors: Markus Malmberg Vesa Anttila P äivi Rautava Jarmo Gunn Ville Kyt ö Source Type: research

Recurrent Strokes as the First Presentation of Occult Pancreatic Cancer; Trousseau Syndrome: A Case Report
We present a case of a 64-year-old female with recurrent ischemic stroke of unknown cause and involving different arterial territories, who was discovered to have metastatic pancreatic cancer. The initial workup with brain imaging revealed multiple acute/subacute ischemic strokes and a negative cardiac assessment. Accordingly, she underwent a whole-body positron emission tomography-computed tomography which revealed a hypermetabolic mass lesion in the pancreaticoduodenal area. Our case indicates that cancer-associated stroke should be seriously evaluated. It demonstrates the critical nature of contemplating hidden cancer i...
Source: Atherosclerosis - January 27, 2022 Category: Cardiology Authors: Firas Al Nidawi Mohamed Wael Mohamed Fatima Taha Daher Alarab Amr Elsayed M Hussein Source Type: research

Minimally ‐invasive parasternal aortic valve replacement–A slow learning curve towards improved outcomes
ConclusionsParasternal minimally ‐invasive aortic valve replacement is a feasible technique associated with a slow learning curve but the potential to achieve improved outcomes. Considering the transcatheter alternatives, the relative risk reduction may be worth investigating in future trials.
Source: Journal of Cardiac Surgery - January 14, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Sophio Tkebuchava, Gloria F ärber, Christoph Sponholz, Frank Fuchs, Petra Heinisch, Michael Bauer, Torsten Doenst Tags: ORIGINAL ARTICLE Source Type: research

Workup and Management of Native and Prosthetic Valve Endocarditis
AbstractInfective endocarditis (IE) is associated with significant serious adverse outcomes including death. IE usually presents with diverse clinical picture and syndromic diagnoses including heart failure, stroke, and peripheral embolization. Given variable, vague, and syndromic presentations, the diagnosis of IE may be delayed for days to weeks. Maintaining a high index of suspicion among clinicians is the key to early recognition of the disease and prompt initiation of antimicrobial therapy to prevent IE-associated mortality and morbidity. Blood culture and echocardiography remain essential tools in the diagnosis of in...
Source: Current Treatment Options in Cardiovascular Medicine - August 7, 2018 Category: Cardiology Source Type: research

Marseille scoring system for empiric treatment of infective endocarditis
AbstractDespite advances in medical, surgical, and critical care, infective endocarditis (IE) remains associated with considerable morbidity and mortality. We evaluated the performance of the Marseille score, including clinical data and biological tests obtained within 2  h, to identify patients at high risk of IE in order to initiate early antimicrobial treatment. This was secondarily confirmed using modified ESC criteria combined with molecular testing and(18)fluorodeoxyglucose-positron emission tomography/computed tomography as diagnostic tools. In a prospective cohort study, we enrolled 484 patients with cardiovascula...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 3, 2018 Category: Microbiology Source Type: research

Successful delayed coiling of a ruptured growing distal posterior cerebral artery mycotic aneurysm.
Abstract Intracranial infectious aneurysm (IIA) is a rare form of cerebrovascular malformation for which obliteration may be undertaken after rupture or non-response to targeted antibiotic therapy. We discuss the case of a 19-year-old man who presented with acute neurologic decline (Glasgow Coma Scale of 8) and endocarditis. CT images demonstrated subarachnoid haemorrhage, hydrocephalus and a mycotic aneurysm on the left posterior cerebral artery. Conservative management was initially decided due to the high risk of stroke and hemianopia. However, it was then escalated to endovascular treatment because of increase...
Source: Neuro-Chirurgie - March 6, 2017 Category: Neurosurgery Authors: Champeaux C, Walker N, Derwin J, Grivas A Tags: Neurochirurgie Source Type: research

A Case Series Of Non-Bacterial Thrombotic Endocarditis Associated With Gynecological Malignancies (P6.248)
Conclusions:NBTE is an important ischemic stroke mechanism. We have reported three cases where the underlying malignancy was gynecological (endometrial, ovarian, and cervical). In the first two cases, the malignancy was discovered during the investigations for the stroke mechanism, while the third had a known underlying malignancy. This series highlights the need to consider gynecological malignancies as an underlying cause of stroke in young women; and that the ischemic event can occur prior to the malignancy diagnosis.Disclosure: Dr. Schabas has nothing to disclose. Dr.Teal has received personal compensation for activiti...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Schabas, A., Teal, P., Yip, S., Mann, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research