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Daily Multivitamins Linked to Improved Cognition in Older People
Taking a daily multivitamin may improve cognitive function in older people, astudy inAlzheimer ’s& Dementia has found. Taking a cocoa supplement, however, does not appear to slow cognitive decline.“There is an urgent need to identify effective strategies to preserve cognitive function to mitigate the heavy societal burden associated with Alzheimer’s disease and related dementia, which affect more than 46 million people worldwide,” wrote Laura D. Baker, Ph.D., of Wake Forest University S chool of Medicine and colleagues. Cocoa extract is rich in compounds called flavanols, and previous small studies suggest that...
Source: Psychiatr News - September 16, 2022 Category: Psychiatry Tags: Alzheimer ' s & Dementia cardiovacsular disease cocoa extract cognitive decline COSMOS-Mind multivitamin Source Type: research

Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders
CONCLUSIONS: Delirium is a common complication of neurological diseases, and it can coexist with catatonia. The recognition of catatonic delirium has clinical significance in terms of etiology, as it was significantly associated with viral and anti-NMDAR encephalitis.PMID:35040665 | DOI:10.1176/appi.neuropsych.18120364
Source: Journal of Neuropsychiatry and Clinical Neurosciences - January 18, 2022 Category: Psychiatry Authors: Jesus Ramirez-Bermudez Angela Medina-Gutierrez Heraclides Gomez-Cianca Patricia Arias Andres P érez-Gonzalez Paulina Ang élica Lebrija-Reyes Mariana Espinola-Nadurille Luis Carlos Aguilar-Venegas Carmen Ojeda-L ópez Miguel Restrepo-Mart ínez Leo Bayli Source Type: research

Tube feeding in patients with dementia is associated with a longer palliative care unit stay
CONCLUSION: The present study showed that, in patients with an established diagnosis of dementia, TF is common and independently associated with a longer length of PCU stay. Nevertheless, the study was underpowered and the results deserve confirmation in larger studies.PMID:34971282 | DOI:10.1002/alz.052919
Source: The Journal of Alzheimers Association - December 31, 2021 Category: Psychiatry Authors: Hilal Zengin Ilker Tasci Source Type: research

Differential Regulation of Angiogenic Gene Networks in Postmortem Brains of Opioid Use Disorder Subjects
This study comprehensively interrogated the transcriptomic and proteomic profiles of the dorsolateral prefrontal cortex (BA9) in subjects with opioid use disorder (OUD), to investigate the molecular effects of opioid abuse in the human brain.
Source: Biological Psychiatry - April 27, 2021 Category: Psychiatry Authors: Emily Mendez, Haichao Wei, Laura Stertz, Gabriel Fries, Ruifeng Hu, Xizi Wu, Katherine Najera, Karla Moriel, Thomas Meyer, Zhongming Zhao, Jiaqian Wu, Consuelo Walss-Bass Source Type: research

The State of Our Understanding of the Pathophysiology and Optimal Treatment of Depression: Glass Half Full or Half Empty?
Abstract Major depressive disorder is a remarkably common and often severe psychiatric disorder associated with high levels of morbidity and mortality. Patients with major depression are prone to several comorbid psychiatric conditions, including posttraumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and substance use disorders, and medical conditions, including cardiovascular disease, diabetes, stroke, cancer, which, coupled with the risk of suicide, result in a shortened life expectancy. The goal of this review is to provide an overview of our current understanding of major depression, ...
Source: The American Journal of Psychiatry - July 31, 2020 Category: Psychiatry Authors: Nemeroff CB Tags: Am J Psychiatry Source Type: research

A cross-sectional study to assess the association between major depression and inflammatory markers in patients with acute ischemic stroke.
Conclusion: This study suggests that in patients who have experienced AIS, there is no significant relationship between major depression and basal proinflammatory cytokines (TNF-α, IL-1 β, IL-18), BDNF, and NSE. PMID: 31142907 [PubMed]
Source: Indian Journal of Psychiatry - June 1, 2019 Category: Psychiatry Tags: Indian J Psychiatry Source Type: research

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