• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Mortality risk after the first occurrence of osteoporotic vertebral compression fractures in the general population: A nationwide cohort study
This study aimed to evaluate mortality risk after the first occurrence of OVCF in the general population using a nationwide dataset from the Korean National Health Insurance System. We identified 291,203 newly diagnosed patients with OVCF and 873,609 patients without OVCF at a ratio of 1:3 matched by sex and age between 2010 and 2012. We investigated the latent characteristics of patients’ demographic information and chronic comorbidities that could affect mortality when diagnosed with OVCF. By comparing the cohort data, the hazar d ratio for subsequent mortality in patients with OVCF was calculated and adjusted based on...
Source: PLoS One - September 14, 2023 Category: Biomedical Science Authors: Hee Jung Son Source Type: research

Pioglitazone Use and Reduced Risk of Dementia in Patients With Diabetes Mellitus With a History of Ischemic Stroke
DISCUSSION: Pioglitazone use is associated with a lower risk of dementia in DM patients, particularly in those with a history of stroke or ischemic heart disease, suggesting the possibility of applying a personalized approach when choosing pioglitazone to suppress dementia in DM patients.PMID:36792375 | DOI:10.1212/WNL.0000000000207069
Source: Cancer Control - February 15, 2023 Category: Cancer & Oncology Authors: Junghee Ha Dong Woo Choi None Kim Keun You Kim Chung Mo Nam Eosu Kim Source Type: research

Changes in coverage among non-elderly adults with chronic diseases following Affordable Care Act implementation
by John D. Goodson, Sara Shahbazi, Zirui Song ImportanceChanges in insurance coverage after the Affordable Care Act (ACA) among non-elderly adults with self-reported chronic conditions across income categories have not been described. ObjectiveTo examine changes in insurance coverage after the ACA among non-elderly adults with chronic conditions across income categories, by geographic region. DesignWe compared self-reported access to health insurance pre-ACA (2010-2013) and post-ACA (2014-2017) for individuals 18-64 years of age with ≥ 2 chronic conditions, including hypertension, heart disease/stroke, emphysema, diabete...
Source: PLoS One - November 30, 2022 Category: Biomedical Science Authors: John D. Goodson Source Type: research

Compression and Expansion of Morbidity-Secular Trends Among Cohorts of the Same Age
CONCLUSION: The notion of morbidity being reduced by compression seems less tenable in view of the double development just mentioned. The findings suggest that the observed secular trend toward better heath among the elderly has not persisted among the more recently born cohorts. This can have negative effects on social security systems, particularly with respect to retirement ages being deferred or made more flexible, as well as the cost of health care.PMID:36300897 | DOI:10.3238/arztebl.m2022.0324
Source: Deutsches Arzteblatt International - October 27, 2022 Category: General Medicine Authors: Siegfried Geyer Sveja Eberhard Source Type: research

The Effect of Chronic Disease Management Program on the Risk of Complications in Patients With Hypertension in Korea
CONCLUSION: The results showed that participants of the chronic disease management program were less likely to have hypertension complications compared to non-participants. Enhancing the participation rate may be related to better outcomes and reducing medical expenses among patients with chronic diseases.PMID:35942556 | DOI:10.3346/jkms.2022.37.e243
Source: Cancer Control - August 9, 2022 Category: Cancer & Oncology Authors: Sang Ah Lee Hyeki Park Woorim Kim Sun Ok Song Hyunsun Lim Sung-Youn Chun Source Type: research

Cancers, Vol. 14, Pages 2977: Association between Breast Cancer and Second Primary Lung Cancer among the Female Population in Taiwan: A Nationwide Population-Based Cohort Study
Conclusion: Patients with breast cancer had a significantly higher risk of developing second primary lung cancer compared with patients without breast cancer, particularly in younger groups and in those without any comorbidities. The special association may be attributed to some potential risk factors such as genetic susceptibility and long-term exposure to PM2.5, and is supposed to increase public awareness. Further studies are necessary given the fact that inherited genotypes, different subtypes of breast cancer and lung cancer, and other unrecognized etiologies may play vital roles in both cancers’ development.
Source: Cancers - June 16, 2022 Category: Cancer & Oncology Authors: Fan-Wen Lin Ming-Hsin Yeh Cheng-Li Lin James Cheng-Chung Wei Tags: Article Source Type: research

Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
CONCLUSIONS: 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.PMID:35396285 | DOI:10.1136/bmjopen-2021-054111
Source: Cancer Control - April 9, 2022 Category: Cancer & Oncology Authors: Peng Yeong Woon Jia-Ying Chien Jen-Hung Wang Yu-Yau Chou Mei-Chen Lin Shun-Ping Huang Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Higher cardiovascular mortality in men with persistent dipstick hematuria
ConclusionsIn men, persistent dipstick hematuria is a significantly risk factor of all-cause mortality, in particular cardiovascular death among general screening participants.
Source: Clinical and Experimental Nephrology - September 21, 2020 Category: Urology & Nephrology Source Type: research

Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea
ConclusionAspirin reduced the risks of MACCE and cancer without increasing the bleeding risk in elderly Koreans with hypertension, T2DM, or dyslipidemia. Moreover, the benefits of the long-term use of aspirin in reducing the risks of MACCE were demonstrated. However, the decision of using aspirin for primary prevention must be carefully made on an individual basis, while estimating the benefit –risk balance of aspirin.
Source: Drugs and Aging - November 21, 2019 Category: Geriatrics Source Type: research

Pages: 1  2  3  4