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Total 196 results found since Jan 2013.

Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research

News at a glance: A win for obesity drugs, NIH unionization roadblocks, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: ScienceNOW - August 10, 2023 Category: Science Source Type: news

News at a glance: A win for obesity drugs, a new infectious disease institute head, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: Science of Aging Knowledge Environment - August 10, 2023 Category: Geriatrics Source Type: research

Association between depression and chronic diseases among middle-aged and older Chinese adults
CONCLUSION: Depressive symptoms were significantly associated with chronic diseases (including diabetes, hypertension, heart disease, and stroke), which suggests that psychological factors, such as depressive symptoms should be taken into consideration in the prevention and control of chronic diseases.PMID:37534639
Source: Cancer Control - August 3, 2023 Category: Cancer & Oncology Authors: C S Zhu Z W Lian Y M Cui Source Type: research

Effect modification of age and hypertension on cancer and prevalence of self ‐reported stroke – A cross‐sectional study
The objective of this study was to examine the effect modification of age on the relationship between cancer and prevalence of self-reported stroke. We used cross-sectional data from the 2015 –2016 iteration of the Canadian Community Health Survey. A multivariable logistic regression model was used to assess the association between cancer and self-reported stroke. Covariates were assessed for effect modification using the maximum likelihood estimation method. We analyzed 86,809 subject s; the prevalence of self-reported stroke was 1.11%. The odds ratio for the association between cancer and self-reported stroke was 1.26 ...
Source: Cancer Medicine - April 21, 2023 Category: Cancer & Oncology Authors: Ronda Lun, Joseph R. Shaw, Danielle Carole Roy, Deborah Siegal, Tim Ramsay, Yue Chen, Dar Dowlatshahi Tags: BRIEF COMMUNICATION Source Type: research

Reach and Impact of In-Person and Remote Delivery Formats of Walk with Ease
Inquiry. 2023 Jan-Dec;60:469580231152314. doi: 10.1177/00469580231152314.ABSTRACTThis descriptive study retrospectively evaluates the reach and impact of cohorts enrolled in Group (in-person, 2017-2020) and Self-Directed (remote, 2019-2020) delivery formats of the evidenced-based health promotion program, Walk with Ease, implemented statewide in North Carolina. An existing dataset consisting of pre- and post-surveys were analyzed for 1,890 participants; 454 (24%) from the Group format and 1,436 (76%) from Self-Directed. Self-Directed participants were younger, had more years of education, represented more Black/African Ame...
Source: Rural Remote Health - February 21, 2023 Category: Rural Health Authors: Nadia Z Mazza Amy Joy Lanou Serena Weisner Source Type: research

Agreement between self-reported diseases from health surveys and national health registry data: a Danish nationwide study
Conclusion Overall, self-reported data were accurate in identifying individuals without the specific disease (ie, specificity and NPV). However, sensitivity, PPV and kappa varied greatly between diseases. These findings should be considered when interpreting similar results from surveys.
Source: Journal of Epidemiology and Community Health - January 10, 2023 Category: Epidemiology Authors: Jensen, H. A. R., Lau, C. J., Davidsen, M., Ekholm, O., Christensen, A. I. Tags: Original research Source Type: research

Chronic non-communicable diseases: Hainan prospective cohort study
Purpose The Hainan Cohort was established to investigate the incidence, morbidity and mortality of non-communicable diseases and their risk factors in the community population. Participants The baseline investigation of the Hainan Cohort study was initiated in five main areas of Hainan, China, from June 2018 to October 2020. A multistage cluster random-sampling method was used to obtain samples from the general population. Baseline assessments included a questionnaire survey, physical examination, blood and urine sample collection, and laboratory measurements, and outdoor environmental data were obtained. Findings to dat...
Source: BMJ Open - November 18, 2022 Category: General Medicine Authors: Gu, X., Lin, L., Zhao, C., Wu, L., Liu, Y., He, L., Lin, G., Lin, Y., Zhang, F. Tags: Open access, Public health Source Type: research

Disparities in Comorbidities in Lung Cancer: Findings From the Behavioral Risk Factor Surveillance System
Conclusion Findings show that there may be differences in patterns of comorbidities among individuals with lung cancer. As we continue to move toward individualized medicine in cancer care, future work in this area should examine social determinants of health and how they may influence the patterns of comorbidities. Implication for Nurses Although nurses may be aware that certain groups have an increased risk for certain comorbid conditions, this study highlights what groups with lung cancer may be more likely to have certain comorbidities. Nurses can assess individuals for comorbidities and provide education on...
Source: Cancer Nursing - October 24, 2022 Category: Nursing Tags: ARTICLES Source Type: research

Self-report of chronic diseases in old-aged individuals: extent of agreement with general practitioner medical records in the German AugUR study
Conclusion Self-reports may be an effective tool to assess diabetes and cancer in observational studies in the old and very old aged. In contrast, self-reports on heart failure, musculoskeletal, kidney or lung diseases may be substantially imprecise.
Source: Journal of Epidemiology and Community Health - October 10, 2022 Category: Epidemiology Authors: Steinkirchner, A. B., Zimmermann, M. E., Donhauser, F. J., Dietl, A., Brandl, C., Koller, M., Loss, J., Heid, I. M., Stark, K. J. Tags: Open access Original research Source Type: research

What is machine learning?
The term machine learning (ML) is emerging more often in the medical literature. There are successful clinical applications of ML with the specialties of ophthalmology and radiology leading the way. For example, in ophthalmology the diagnosis of diabetic retinopathy and retinopathy of prematurity,1 and in radiology the diagnosis of stroke or cancers from digital images is promising.2 This success is expected to expand into other medical disciplines including general paediatrics and its subspecialties. Therefore, healthcare practitioners and researchers are most likely to benefit from getting familiar with ML terminology in...
Source: Archives of Disease in Childhood - Education and Practice - September 19, 2022 Category: Pediatrics Authors: Baloglu, O., Latifi, S. Q., Nazha, A. Tags: Research in practice Source Type: research