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Total 627 results found since Jan 2013.
Sex and gender differences in the use of oral anticoagulants for non-valvular atrial fibrillation: A population-based cohort study in primary health care in catalonia
Conclusion: We described the dose adequacy of patients receiving DOAC, finding a high frequency of underdosing, and significantly higher in women in comparison with men. Adherence was generally high, only with higher levels in women for rivaroxaban. Persistence during the first year of treatment was also high in general, being significantly more persistent women than men in the case of dabigatran and edoxaban. Dose inadequacy, lack of adherence and of persistence can result in less effective and safe treatments. It is necessary to conduct studies analysing sex and gender differences in health and disease.
Source: Frontiers in Pharmacology - February 7, 2023 Category: Drugs & Pharmacology Source Type: research
Your native tongue holds a special place in your brain, even if you speak 10 languages
This study “contributes to our understanding of how our brain learns new things,” says Augusto Buchweitz, a cognitive neuroscientist at the University of Connecticut, Storrs, who was not involved in the work. “The earlier you learn something, the more your brain [adapts] and probably uses less resources.”
Scientists have largely ignored what’s going on inside the brains of polyglots—people who speak more than five languages—says Ev Fedorenko, a cognitive neuroscientist at the Massachusetts Institute of Technology who led the new study. “There’s oodles of work on individuals whose language systems are...
Source: Science of Aging Knowledge Environment - February 3, 2023 Category: Geriatrics Source Type: research
Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus
Left ventricular thrombus (LVT) occurs in acute myocardial infarction (AMI) and in ischemic and nonischemic cardiomyopathies.1,2 LVT may result in embolic stroke.3 We read with interest the study by Lorente-Ros et al4 published in the American Journal of Cardiology. That study, conducted in a Spanish cohort, found that prolonged anticoagulation>12 months for LVT was associated with lower stroke risk. We aimed to study the generalizability of these results in an Asian population because the original article was a single-center study with limited representation.
Source: The American Journal of Cardiology - January 24, 2023 Category: Cardiology Authors: Fang Qin Goh, Aloysius S.T. Leow, Jamie S.Y. Ho, Benjamin Y.Q. Tan, Leonard L.L. Yeo, Ching-Hui Sia Source Type: research
Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study
Diabetes Metab. 2023 Jan 3:101418. doi: 10.1016/j.diabet.2022.101418. Online ahead of print.ABSTRACTBACKGROUND: Continued expansion of indications for sodium-glucose cotransporter-2 inhibitors increases importance of evaluating cardiovascular and kidney efficacy and safety of empagliflozin in patients with type 2 diabetes compared to similar therapies.METHODS: The EMPRISE Europe and Asia study is a non-interventional cohort study using data from 2014-2019 in seven European (Denmark, Finland, Germany, Norway, Spain, Sweden, United Kingdom) and four Asian (Israel, Japan, South Korea, Taiwan) countries. Patients with type 2 d...
Source: Diabetes and Metabolism - January 7, 2023 Category: Endocrinology Authors: Avraham Karasik Stefanie Lanzinger Elise Chia-Hui Tan Daisuke Yabe Dae Jung Kim Wayne H-H Sheu Cheli Melzer-Cohen Reinhard W Holl Kyoung Hwa Ha Kamlesh Khunti Francesco Zaccardi Anuradhaa Subramanian Krishnarajah Nirantharakumar Thomas Nystr öm Leo Niska Source Type: research
IJERPH, Vol. 20, Pages 995: A Cross-Sectional Study: Determining Factors of Functional Independence and Quality of Life of Patients One Month after Having Suffered a Stroke
Conclusions: the type of dwelling, age, cognitive ability and functional capacity of the affected upper limb are determining aspects in functional independence and QoL during the first weeks after a stroke.
Source: International Journal of Environmental Research and Public Health - January 5, 2023 Category: Environmental Health Authors: Josefa Gonz ález-Santos Paula Rodr íguez-Fernández Roc ío Pardo-Hernández Jer ónimo J. González-Bernal Jessica Fern ández-Solana Mirian Santamar ía-Peláez Tags: Article Source Type: research
Identification of Secondary Prevention Patients Eligible for PCSK9 Inhibitors Therapy According to the Routine Clinical Practice in Spain
ConclusionUp to 82% of patients with atherosclerotic CV disease do not achieve LDL-C levels recommended by the 2019 ESC/EAS guidelines despite being on optimized oral LLT therapy. In 17.9% of these patients LDL-C levels exceed 100 mg/dL, being eligible for PCSK9i in Spain.
Source: Advances in Therapy - December 16, 2022 Category: Drugs & Pharmacology Source Type: research
EE498 Cost of Follow-Up After an Ischemic Cerebrovascular Event in Patients With Atherosclerotic Cardiovascular Disease in Spain: Results from the Reality Study
Ischemic cerebrovascular events stroke and transient ischemic attack (TIA) are a cause of morbidity and mortality in developed countries and entails a high resources consumption and costs for health systems. These patients have an increased risk of suffering a new event with the consequent additional resource consumption and an increased follow-up cost.
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: M Castellanos, JM Games, JM Mostaza, I Egocheaga, J Gomez Cerezo, R Campuzano, V Pallares, V Barrios, N Morant Talamante, A Sicras-Mainar, I P érez Román, JM Rodriguez Barrios, FJ Parrondo García, I Martinez Source Type: research
RWD149 Reduction in Ischemic Stroke Rates in Patients With Non-Valvular Atrial Fibrillation During the Period 2013-2020: A Real-Life Study in Spain
The aim of this study is to analyze the variations in the incidence of cardiovascular events and mortality rates in patients with non-valvular atrial fibrillation (NVAF) receiving antithrombotic treatment (VKA, NOAC or antiplatelet drugs) between 2013 and 2020. In addition, this study estimates the impact of these variations in the use of healthcare resources and costs in Spain.
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: O Delgado, A Sicras-Mainar, I P érez Román, J Salazar, MI del Campo Alonso, A Echeto, D Vilanova, J Comin-Colet Source Type: research
Autopsy and its role in Franco ’s dictatorship: a case of the last Republican mayor of the town Calera y Chozas (Toledo, Spain)
AbstractIn the town of Calera y Chozas (Spain), five mass graves containing the remains of 28 individuals were discovered during a 2012 excavation. The witnesses and historical evidence indicated that the body of the last Republican mayor of the town, Felipe Fern ández Varela, who had died in September 1939, was located in the mass grave designated as no. 1. Within this particular grave, only two bodies were found. Anthropological analysis showed that the first individual was significantly younger than 50 years, being the mayor’s age at the time of death , while the age of the second individual was closer to 50. This s...
Source: Forensic Science, Medicine, and Pathology - November 17, 2022 Category: Forensic Medicine Source Type: research
IJERPH, Vol. 19, Pages 14964: Reliability and Validity of the Motor Activity Log (MAL-30) Scale for Post-Stroke Patients in a Spanish Sample
Conclusions: The MAL-30 instrument can be considered a valid and reliable tool for assessing the quantity and quality of the use of the affected upper limb in the performance of the activities of daily living and the instrumental activities of daily living after stroke in a Spanish sample.
Source: International Journal of Environmental Research and Public Health - November 14, 2022 Category: Environmental Health Authors: Mirian Santamar ía-Peláez Roc ío Pardo-Hernández Jer ónimo J. González-Bernal Ra úl Soto-Cámara Josefa Gonz ález-Santos Jessica Fern ández-Solana Tags: Article Source Type: research
IJERPH, Vol. 19, Pages 14918: Psychometric Properties of the Action Research Arm Test (ARAT) Scale in Post-Stroke Patients & mdash;Spanish Population
In conclusion, the ARAT can be considered a valid and reliable instrument for the evaluation of upper limb function in post-stroke patients.
Source: International Journal of Environmental Research and Public Health - November 13, 2022 Category: Environmental Health Authors: Jessica Fern ández-Solana Roc ío Pardo-Hernández Jer ónimo J. González-Bernal Esteban S ánchez-González Josefa Gonz ález-Santos Ra úl Soto-Cámara Mirian Santamar ía-Pelaez Tags: Article Source Type: research
