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Therapy: Antiviral Therapy
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Total 2209 results found since Jan 2013.
In Silico Identification and Analysis of Potentially Bioactive Antiviral Phytochemicals against SARS-CoV-2: A Molecular Docking and Dynamics Simulation Approach
Biomed Res Int. 2023 May 11;2023:5469258. doi: 10.1155/2023/5469258. eCollection 2023.ABSTRACTSARS-CoV-2, a deadly coronavirus sparked COVID-19 pandemic around the globe. With an increased mutation rate, this infectious agent is highly transmissible inducing an escalated rate of infections and death everywhere. Hence, the discovery of a viable antiviral therapy option is urgent. Computational approaches have offered a revolutionary framework to identify novel antimicrobial treatment regimens and allow a quicker, cost-effective, and productive conversion into the health center by evaluating preliminary and safety investigat...
Source: Biomed Res - May 22, 2023 Category: Research Authors: Sajal Kumar Halder Ive Sultana Md Nazmussakib Shuvo Aparna Shil Mahbubul Kabir Himel Md Ashraful Hasan Mohammad Mahfuz Ali Khan Shawan Source Type: research
Predictive plasma biomarkers of long-term increase in hepatic steatosis index after HCV eradication in HIV/HCV-coinfected patients
Biomed Pharmacother. 2023 May 20;164:114913. doi: 10.1016/j.biopha.2023.114913. Online ahead of print.ABSTRACTHepatic steatosis is a common condition found in the liver of hepatitis C virus (HCV)-infected patients, contributing to more severe forms of liver disease. In addition, the human immunodeficiency virus (HIV) may accelerate this process. Alternatively, several immune checkpoint proteins have been reported to be upregulated and correlated with disease progression during HCV and HIV infections. In steatosis, a detrimental immune system activation has been established; however, the role of the immune checkpoints has n...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 22, 2023 Category: Drugs & Pharmacology Authors: Rub én Martín-Escolano Ana Virseda-Berdices Juan Berenguer Juan Gonz ález-García Oscar Brochado-Kith Amanda Fern ández-Rodríguez Cristina D íez Victor Honta ñon Salvador Resino Mar ía Ángeles Jiménez-Sousa GeSIDA 10318 Study Group Source Type: research
Prevalence of inappropriate use of nirmatrelvir-ritonavir antiviral therapy in hospitalized patients: A multicenter retrospective study in China
CONCLUSIONS: The proportion of inappropriate use of NMVr was particularly high in the Chinese hospital setting, highlighting the urgent need to improve the appropriate use of NMVr.PMID:37211263 | DOI:10.1016/j.ijantimicag.2023.106857
Source: Cancer Control - May 21, 2023 Category: Cancer & Oncology Authors: Changcheng Shi Lei Qiu Juanjuan Zhuo Yingying Fang Limin Wang Junbo Xia Shuying Wang Qing Luo Kang Zhou Yongchen Li Qingyu Li Gang Wang Nengming Lin Source Type: research
Case Report: Multiple Organ Failure Caused by Hemorrhagic Fever with Renal Syndrome
This report describes the case of a 55-year-old man with complaints of fever, vomiting, and diarrhea. His symptoms showed no significant improvement after routine anti-infective, antipyretic, and other symptomatic supportive treatments administered at a local clinic. During these treatments, the patient had progressive oliguria; after 3 days, he also developed multiple organ failures, such as the liver and kidney, and was examined for positive serum IgM antibodies to hemorrhagic fever during treatment at our hospital. The patient was finally diagnosed with HFRS followed by multiple organ failure. After antiviral therapy, i...
Source: Am J Trop Med Hyg - May 15, 2023 Category: Infectious Diseases Authors: Rui Wang Xiang-Yang Zhao Xiao-Jun Liu Miao Zhang Yan-Ting Sun Xiao Ning Jian Xu Chan-Yuan Bu Source Type: research
