Filtered By:
Specialty: Physiology

This page shows you your search results in order of date. This is page number 4.

Order by Relevance | Date

Total 33096 results found since Jan 2013.

The Therapeutic Role of Inspiratory Muscle Training in The Management of Asthma: A Narrative Review
Am J Physiol Regul Integr Comp Physiol. 2023 Sep 18. doi: 10.1152/ajpregu.00325.2022. Online ahead of print.ABSTRACTAsthma is a disorder of the airways characterized by chronic airway inflammation, hyperresponsiveness, and variable recurring airway obstruction. Treatment options for asthma include pharmacological strategies, while non-pharmacological strategies are limited. Established pharmacological approaches to treating asthma may cause unwanted side effects and do not always afford adequate protection against asthma, possibly due to an individual's variable response to medications. A potential non-pharmacological inte...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Abigail S Sogard Timothy D Mickleborough Source Type: research

Early-life sodium deprivation programs long-term changes in ingestive behaviors and energy expenditure in C57BL/6J mice
Am J Physiol Regul Integr Comp Physiol. 2023 Sep 18. doi: 10.1152/ajpregu.00137.2023. Online ahead of print.ABSTRACTPostnatal growth failure remains a significant problem for infants born prematurely, despite aggressive efforts to improve perinatal nutrition. Though often dysregulated in early life when children are born preterm, sodium (Na) homeostasis is vital to achieve optimal growth. We hypothesize that insufficient Na supply in this critical period contributes to growth restriction and programmed risks for cardiometabolic disease in later adulthood. Thus, we sought to ascertain the effects of prolonged versus early-l...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Alisha A Ziegler Samuel B R Lawton Connie C Grobe John J Reho Bonnie P Freudinger Colin M L Burnett Pablo Nakagawa Justin L Grobe Jeffrey L Segar Source Type: research

Ponderings on Peer Review: Part 3. Grant Critiques
The objective of stage 1 of the process is to establish the scientific merit of the grant proposal. For that phase, I discuss grant review panels, reviewer qualifications and responsibilities, how reviewers are identified and selected, pre-review meeting activities, activities during the review panel meeting, grant review criteria and scoring scales, and post-meeting activities. I also note 2 mechanisms that provide "pre-peer review" advice and recommendations for grant applications under development. I then describe the events associated with stage 2 of the peer review process in which grant funding agencies consider appl...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Douglas R Seals Source Type: research

The Therapeutic Role of Inspiratory Muscle Training in The Management of Asthma: A Narrative Review
Am J Physiol Regul Integr Comp Physiol. 2023 Sep 18. doi: 10.1152/ajpregu.00325.2022. Online ahead of print.ABSTRACTAsthma is a disorder of the airways characterized by chronic airway inflammation, hyperresponsiveness, and variable recurring airway obstruction. Treatment options for asthma include pharmacological strategies, while non-pharmacological strategies are limited. Established pharmacological approaches to treating asthma may cause unwanted side effects and do not always afford adequate protection against asthma, possibly due to an individual's variable response to medications. A potential non-pharmacological inte...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Abigail S Sogard Timothy D Mickleborough Source Type: research

Early-life sodium deprivation programs long-term changes in ingestive behaviors and energy expenditure in C57BL/6J mice
Am J Physiol Regul Integr Comp Physiol. 2023 Sep 18. doi: 10.1152/ajpregu.00137.2023. Online ahead of print.ABSTRACTPostnatal growth failure remains a significant problem for infants born prematurely, despite aggressive efforts to improve perinatal nutrition. Though often dysregulated in early life when children are born preterm, sodium (Na) homeostasis is vital to achieve optimal growth. We hypothesize that insufficient Na supply in this critical period contributes to growth restriction and programmed risks for cardiometabolic disease in later adulthood. Thus, we sought to ascertain the effects of prolonged versus early-l...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Alisha A Ziegler Samuel B R Lawton Connie C Grobe John J Reho Bonnie P Freudinger Colin M L Burnett Pablo Nakagawa Justin L Grobe Jeffrey L Segar Source Type: research

Ponderings on Peer Review: Part 3. Grant Critiques
The objective of stage 1 of the process is to establish the scientific merit of the grant proposal. For that phase, I discuss grant review panels, reviewer qualifications and responsibilities, how reviewers are identified and selected, pre-review meeting activities, activities during the review panel meeting, grant review criteria and scoring scales, and post-meeting activities. I also note 2 mechanisms that provide "pre-peer review" advice and recommendations for grant applications under development. I then describe the events associated with stage 2 of the peer review process in which grant funding agencies consider appl...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 18, 2023 Category: Physiology Authors: Douglas R Seals Source Type: research

Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy
Light Sci Appl. 2023 Sep 18;12(1):231. doi: 10.1038/s41377-023-01275-3.ABSTRACTBeing the largest and most accessible organ of the human body, the skin could offer a window to diabetes-related complications on the microvasculature. However, skin microvasculature is typically assessed by histological analysis, which is not suited for applications to large populations or longitudinal studies. We introduce ultra-wideband raster-scan optoacoustic mesoscopy (RSOM) for precise, non-invasive assessment of diabetes-related changes in the dermal microvasculature and skin micro-anatomy, resolved with unprecedented sensitivity and det...
Source: Appl Human Sci - September 17, 2023 Category: Physiology Authors: Hailong He Nikolina-Alexia Fasoula Angelos Karlas Murad Omar Juan Aguirre Jessica Lutz Michael Kallmayer Martin F üchtenbusch Hans-Henning Eckstein Annette Ziegler Vasilis Ntziachristos Source Type: research

Deciphering calcium signals in cells and tissues with tailored probes and models
J Physiol. 2023 Sep 16. doi: 10.1113/JP285037. Online ahead of print.NO ABSTRACTPMID:37715737 | DOI:10.1113/JP285037
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Nicolas Demaurex Source Type: research

Age-related changes in P2Y receptor signalling in mouse cochlear supporting cells
J Physiol. 2023 Sep 16. doi: 10.1113/JP284980. Online ahead of print.ABSTRACTOur sense of hearing depends on the function of a specialised class of sensory cells, the hair cells, which are found in the organ of Corti of the mammalian cochlea. The unique physiological environment in which these cells operate is maintained by a syncitium of non-sensory supporting cells, which are crucial for regulating cochlear physiology and metabolic homeostasis. Despite their importance for cochlear function, the role of these supporting cells in age-related hearing loss, the most common sensory deficit in the elderly, is poorly understoo...
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Sarah A Hool Jing-Yi Jeng Daniel J Jagger Walter Marcotti Federico Ceriani Source Type: research

Deciphering calcium signals in cells and tissues with tailored probes and models
J Physiol. 2023 Sep 16. doi: 10.1113/JP285037. Online ahead of print.NO ABSTRACTPMID:37715737 | DOI:10.1113/JP285037
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Nicolas Demaurex Source Type: research

Age-related changes in P2Y receptor signalling in mouse cochlear supporting cells
J Physiol. 2023 Sep 16. doi: 10.1113/JP284980. Online ahead of print.ABSTRACTOur sense of hearing depends on the function of a specialised class of sensory cells, the hair cells, which are found in the organ of Corti of the mammalian cochlea. The unique physiological environment in which these cells operate is maintained by a syncitium of non-sensory supporting cells, which are crucial for regulating cochlear physiology and metabolic homeostasis. Despite their importance for cochlear function, the role of these supporting cells in age-related hearing loss, the most common sensory deficit in the elderly, is poorly understoo...
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Sarah A Hool Jing-Yi Jeng Daniel J Jagger Walter Marcotti Federico Ceriani Source Type: research

Deciphering calcium signals in cells and tissues with tailored probes and models
J Physiol. 2023 Sep 16. doi: 10.1113/JP285037. Online ahead of print.NO ABSTRACTPMID:37715737 | DOI:10.1113/JP285037
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Nicolas Demaurex Source Type: research

Age-related changes in P2Y receptor signalling in mouse cochlear supporting cells
J Physiol. 2023 Sep 16. doi: 10.1113/JP284980. Online ahead of print.ABSTRACTOur sense of hearing depends on the function of a specialised class of sensory cells, the hair cells, which are found in the organ of Corti of the mammalian cochlea. The unique physiological environment in which these cells operate is maintained by a syncitium of non-sensory supporting cells, which are crucial for regulating cochlear physiology and metabolic homeostasis. Despite their importance for cochlear function, the role of these supporting cells in age-related hearing loss, the most common sensory deficit in the elderly, is poorly understoo...
Source: The Journal of Physiology - September 16, 2023 Category: Physiology Authors: Sarah A Hool Jing-Yi Jeng Daniel J Jagger Walter Marcotti Federico Ceriani Source Type: research