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Financial risk protection in private health insurance: empirical evidence on catastrophic and impoverishing spending from Germany's dual insurance system
This study provides evidence on financial protection in PHI for the case of Germany's dual insurance system of PHI and SHI, where PHI covers 11% of the population. Linked survey and claims data of PHI insureds (n = 3105) and population-wide household budget data (n = 42,226) are used to compute the prevalence of catastrophic health expenditures (CHE), i.e. the share of households whose out-of-pocket payments either exceed 40% of their capacity-to-pay or push them (further) into poverty. Despite comparatively high out-of-pocket payments, CHE is low in German PHI. It only affects the poor. Key to low financial burden seems t...
Source: Health Economics, Policy, and Law - September 7, 2023 Category: Health Management Authors: Philipp Hengel Miriam Bl ümel Martin Siegel Katharina Achstetter Julia K öppen Reinhard Busse Source Type: research

Moderating role of green innovation and fiscal expenditure towards achieving the Sustainable Development Agenda 2030 at provincial-level in China: policy implication from green total factor productivity
Environ Sci Pollut Res Int. 2023 Sep 6. doi: 10.1007/s11356-023-29551-0. Online ahead of print.ABSTRACTAmidst resource loss and environmental protection constraints, achieving green development necessitates enhancing green total factor productivity (GTFP) as a means of promoting rational and efficient resource allocation, thereby balancing economic growth and environmental preservation. Meanwhile, literature on the subject matter of GTFP from a sustainability viewpoint is minimal. As a result, this study employs the panel dataset from 30 provinces of China spanning the period 2005 to 2020 and utilizes the method of moments...
Source: Environmental Science and Pollution Research International - September 6, 2023 Category: Environmental Health Authors: Yongzhong Jiang Muhammad Ramzan Abraham Ayobamiji Awosusi Tomiwa Sunday Adebayo Source Type: research

Effect of agricultural carbon emissions on farmers' health expenditure of China: evidence from the educational threshold effect
Environ Sci Pollut Res Int. 2023 Sep 5. doi: 10.1007/s11356-023-29559-6. Online ahead of print.ABSTRACTEnvironmental pollution, especially agricultural carbon emissions (ACE), has led to public health problems to rural areas in China and accompanied by a heavy medical economic burden. However, most studies on carbon dioxide emissions and healthcare expenditures focused on the industrial sector, and the effect of ACE was overlooked. Therefore, studying the effect of ACE on rural residents' healthcare expenditures (NHCE) is not only conducive to accelerating the low-carbon transformation of agriculture but also has important...
Source: Environmental Science and Pollution Research International - September 5, 2023 Category: Environmental Health Authors: Yuling Hu Junyin Tan Na Zhang Chengjie Liu Source Type: research

Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia
Discussions were held on etiological diseases, essential diagnostic items for cachexia, including subjective and objective symptoms and biomarkers, and significant clinical outcomes. The consensus highlighted the importance of multiple diagnostic factors for cachexia, including chronic diseases, either or both weight loss or low body mass index, and at least one of the following: anorexia, decreased grip strength (<28 kg in men and <18 kg in women), or elevated C-reactive protein levels (>5 mg/L [0.5 mg/dL]). The AWGC proposed a significant weight change of 2% or more over a 3-6 month period and suggested a tentat...
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Hidenori Arai Keisuke Maeda Hidetaka Wakabayashi Tateaki Naito Masaaki Konishi Prasert Assantachai Wai Tung Auyeung Chalobol Chalermsri Wei Chen Justin Chew Ming-Yueh Chou Chih-Cheng Hsu Allyn Hum In Gyu Hwang Toshimi Kaido Lin Kang Shahrul Bahyah Kamaruz Source Type: research

Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation
Pflugers Arch. 2023 Sep 1. doi: 10.1007/s00424-023-02854-4. Online ahead of print.ABSTRACTSkeletal muscle relies on mitochondria for sustainable ATP production, which may be impacted by reduced oxygen availability (hypoxia). Compared with long-term hypoxia, the mechanistic in vivo response to acute hypoxia remains elusive. Therefore, we aimed to provide an integrated description of the Musculus gastrocnemius response to acute hypoxia. Fasted male C57BL/6JOlaHsd mice, fed a 40en% fat diet for six weeks, were exposed to 12% O2 normobaric hypoxia or normoxia (20.9% O2) for six hours (n = 12 per group). Whole-body energy metab...
Source: Pflugers Archiv : European Journal of Physiology - September 1, 2023 Category: Physiology Authors: Jingyi Song Loes P M Duivenvoorde Sander Grefte Ondrej Kuda Felipe Mart ínez-Ramírez Inge van der Stelt Dimitra Mastorakou Evert M van Schothorst Jaap Keijer Source Type: research

Double knockout of FFAR4 and FGF21 aggravates metabolic disorders in mice
Int J Biol Macromol. 2023 Aug 30:126553. doi: 10.1016/j.ijbiomac.2023.126553. Online ahead of print.ABSTRACTSeveral investigations have examined the involvement of free fatty acid receptor 4 (FFAR4) in metabolic disorders, but its action remains controversial. To investigate whether endogenous fibroblast growth factor 21 (FGF21)-mediated signaling controls the metabolic status in FFAR4-deficient mice, we generated FFAR4/FGF21 double knockout (DKO) mice. We also evaluated the role of FGF21 on glucose and lipid metabolism in FFAR4 KO mice fed a high-fat diet. Levels of FGF21 were significantly increased in FFAR4-deficient mi...
Source: International Journal of Biological Macromolecules - September 1, 2023 Category: Biochemistry Authors: Lengyun Wei Xianlong Ye Siyuan Cui Dashuai Li Shenglong Zhu Source Type: research

Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation
Pflugers Arch. 2023 Sep 1. doi: 10.1007/s00424-023-02854-4. Online ahead of print.ABSTRACTSkeletal muscle relies on mitochondria for sustainable ATP production, which may be impacted by reduced oxygen availability (hypoxia). Compared with long-term hypoxia, the mechanistic in vivo response to acute hypoxia remains elusive. Therefore, we aimed to provide an integrated description of the Musculus gastrocnemius response to acute hypoxia. Fasted male C57BL/6JOlaHsd mice, fed a 40en% fat diet for six weeks, were exposed to 12% O2 normobaric hypoxia or normoxia (20.9% O2) for six hours (n = 12 per group). Whole-body energy metab...
Source: Pflugers Archiv : European Journal of Physiology - September 1, 2023 Category: Physiology Authors: Jingyi Song Loes P M Duivenvoorde Sander Grefte Ondrej Kuda Felipe Mart ínez-Ramírez Inge van der Stelt Dimitra Mastorakou Evert M van Schothorst Jaap Keijer Source Type: research

Double knockout of FFAR4 and FGF21 aggravates metabolic disorders in mice
Int J Biol Macromol. 2023 Aug 30:126553. doi: 10.1016/j.ijbiomac.2023.126553. Online ahead of print.ABSTRACTSeveral investigations have examined the involvement of free fatty acid receptor 4 (FFAR4) in metabolic disorders, but its action remains controversial. To investigate whether endogenous fibroblast growth factor 21 (FGF21)-mediated signaling controls the metabolic status in FFAR4-deficient mice, we generated FFAR4/FGF21 double knockout (DKO) mice. We also evaluated the role of FGF21 on glucose and lipid metabolism in FFAR4 KO mice fed a high-fat diet. Levels of FGF21 were significantly increased in FFAR4-deficient mi...
Source: International Journal of Biological Macromolecules - September 1, 2023 Category: Biochemistry Authors: Lengyun Wei Xianlong Ye Siyuan Cui Dashuai Li Shenglong Zhu Source Type: research

The perspectives of NETosis on the progression of obesity and obesity-related diseases: mechanisms and applications
Front Cell Dev Biol. 2023 Aug 15;11:1221361. doi: 10.3389/fcell.2023.1221361. eCollection 2023.ABSTRACTObesity is a disease commonly associated with urbanization and can also be characterized as a systemic, chronic metabolic condition resulting from an imbalance between energy intake and expenditure. The World Health Organization (WHO) has identified obesity as the most serious chronic disease that is increasingly prevalent in the world population. If left untreated, it can lead to dangerous health issues such as hypertension, hyperglycemia, hyperlipidemia, hyperuricemia, nonalcoholic steatohepatitis, atherosclerosis, and ...
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Jinyu Li Lijia Yin Siyi Chen Zelin Li Jiatong Ding Jiaqiang Wu Kangping Yang Jixiong Xu Source Type: research

Resting energy metabolism and sweet taste preference during the menstrual cycle in healthy women
Br J Nutr. 2023 Aug 29:1-19. doi: 10.1017/S0007114523001927. Online ahead of print.ABSTRACTDifferences in blood concentration of sex hormones in the follicular (FP) and luteal (LP) phases may influence energy metabolism in women. We compared fasting energy metabolism and sweet taste preference on a representative day of the FP and LP in 20 healthy women (25.3±5.1 years, BMI: 22.2±2.2 kg/m2) with regular self-reported menses and without the use of hormonal contraceptives. From the self-reported duration of the three prior menstrual cycles, the predicted FP and LP visits were scheduled for days 5 to 12 and 20 to 25 after m...
Source: The British Journal of Nutrition - August 29, 2023 Category: Nutrition Authors: Lorena Malo-Vintimilla Carolina Aguirre Angie Vergara Rodrigo Fern ández-Verdejo Jose E Galgani Source Type: research

Factors correlated with neuropathic pain among industrial workers in Vietnam: a multi-site cross-sectional study
DISCUSSION: These results may inform the adoption of pain screening and other programs that increase health care access for this population, as well as more stringent occupational health and safety standards.PMID:37637802 | PMC:PMC10451076 | DOI:10.3389/fpubh.2023.1007483
Source: Pain Physician - August 28, 2023 Category: Anesthesiology Authors: Tham Thi Nguyen Huong Van Nguyen Hai Minh Vu Ryan G Chiu Quang Nhat Nguyen Thao Thi Phuong Nguyen Long Hoang Nguyen Anh Kim Dang Khanh Nam Do Tu Huu Nguyen Vu Nguyen Anh Toan Ngo Tung Hoang Tran Carl A Latkin Cyrus S H Ho Roger C M Ho Source Type: research