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Source: International Journal of Oncology
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Corrigendum MicroRNA ‑133b targets TGFβ receptor I to inhibit TGF‑β‑induced epithelial‑to‑mesenchymal transition and metastasis by suppressing the TGF‑β/SMAD pathway in breast cancer
Int J Oncol. 2023 Jul;63(1):83. doi: 10.3892/ijo.2023.5531. Epub 2023 Jun 9.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, for the MCF‑7 cell migration assays shown in Fig. 3C on p. 1105, the representative images selected for the 'TGF‑β+ / miR‑NC' and 'TGF‑β1‑ / miR‑NC' experiments were found to be overlapping, such that the data appeared to have been derived from the same original source. After having consulted their original data, the authors noted that the error had arisen during the process of assembling this figure, and the data chosen f...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Shengjie Wang Mingliang Huang Zichen Wang Wan Wang Zhiyuan Zhang Shuting Qu Chun Liu Source Type: research
Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway
Int J Oncol. 2023 Jul;63(1):84. doi: 10.3892/ijo.2023.5532. Epub 2023 Jun 9.ABSTRACTBladder cancer (BC) is a heterogeneous disease, and pyrroline‑5‑carboxylate reductase 1 (PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC progression. In the present study, si‑PYCR1 was loaded into bone marrow mesenchymal stem cell (BMSC)‑derived exosomes (Exos) in BC. First, PYCR1 levels in BC tissues/cells were assessed, and cell proliferation, invasion, and migration were evaluated. Aerobic glycolysis levels (glucose uptake, lactate production, ATP production, and the expression of relevant enzymes)...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Zhuo Li Ying Jiang Jian Liu Huifeng Fu Quan Yang Wei Song Yuanwei Li Source Type: research
Corrigendum MicroRNA ‑133b targets TGFβ receptor I to inhibit TGF‑β‑induced epithelial‑to‑mesenchymal transition and metastasis by suppressing the TGF‑β/SMAD pathway in breast cancer
Int J Oncol. 2023 Jul;63(1):83. doi: 10.3892/ijo.2023.5531. Epub 2023 Jun 9.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, for the MCF‑7 cell migration assays shown in Fig. 3C on p. 1105, the representative images selected for the 'TGF‑β+ / miR‑NC' and 'TGF‑β1‑ / miR‑NC' experiments were found to be overlapping, such that the data appeared to have been derived from the same original source. After having consulted their original data, the authors noted that the error had arisen during the process of assembling this figure, and the data chosen f...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Shengjie Wang Mingliang Huang Zichen Wang Wan Wang Zhiyuan Zhang Shuting Qu Chun Liu Source Type: research
Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway
Int J Oncol. 2023 Jul;63(1):84. doi: 10.3892/ijo.2023.5532. Epub 2023 Jun 9.ABSTRACTBladder cancer (BC) is a heterogeneous disease, and pyrroline‑5‑carboxylate reductase 1 (PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC progression. In the present study, si‑PYCR1 was loaded into bone marrow mesenchymal stem cell (BMSC)‑derived exosomes (Exos) in BC. First, PYCR1 levels in BC tissues/cells were assessed, and cell proliferation, invasion, and migration were evaluated. Aerobic glycolysis levels (glucose uptake, lactate production, ATP production, and the expression of relevant enzymes)...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Zhuo Li Ying Jiang Jian Liu Huifeng Fu Quan Yang Wei Song Yuanwei Li Source Type: research
Corrigendum MicroRNA ‑133b targets TGFβ receptor I to inhibit TGF‑β‑induced epithelial‑to‑mesenchymal transition and metastasis by suppressing the TGF‑β/SMAD pathway in breast cancer
Int J Oncol. 2023 Jul;63(1):83. doi: 10.3892/ijo.2023.5531. Epub 2023 Jun 9.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, for the MCF‑7 cell migration assays shown in Fig. 3C on p. 1105, the representative images selected for the 'TGF‑β+ / miR‑NC' and 'TGF‑β1‑ / miR‑NC' experiments were found to be overlapping, such that the data appeared to have been derived from the same original source. After having consulted their original data, the authors noted that the error had arisen during the process of assembling this figure, and the data chosen f...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Shengjie Wang Mingliang Huang Zichen Wang Wan Wang Zhiyuan Zhang Shuting Qu Chun Liu Source Type: research
Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway
Int J Oncol. 2023 Jul;63(1):84. doi: 10.3892/ijo.2023.5532. Epub 2023 Jun 9.ABSTRACTBladder cancer (BC) is a heterogeneous disease, and pyrroline‑5‑carboxylate reductase 1 (PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC progression. In the present study, si‑PYCR1 was loaded into bone marrow mesenchymal stem cell (BMSC)‑derived exosomes (Exos) in BC. First, PYCR1 levels in BC tissues/cells were assessed, and cell proliferation, invasion, and migration were evaluated. Aerobic glycolysis levels (glucose uptake, lactate production, ATP production, and the expression of relevant enzymes)...
Source: International Journal of Oncology - June 9, 2023 Category: Cancer & Oncology Authors: Zhuo Li Ying Jiang Jian Liu Huifeng Fu Quan Yang Wei Song Yuanwei Li Source Type: research
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma
Int J Oncol. 2023 Jul;63(1):82. doi: 10.3892/ijo.2023.5530. Epub 2023 Jun 2.ABSTRACTCisplatin is the standard chemotherapeutic drug used for the treatment of esophageal squamous cell carcinoma (ESCC). Acquired cisplatin resistance is the primary obstacle to prolonging patient survival time. Here, the therapeutic effects of mitochondrial calcium uniporter (MCU) inhibition on tumor growth and cisplatin resistance in ESCC were assessed. MCU was stably overexpressed or knocked down in three ESCC cell lines and three cisplatin‑resistant ESCC cell lines. Then, proliferation, migration, and mitochondrial membrane potential (MMP...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Miao Xiaofei Wang Yafang Lai Ying Huang Hua Yin Xiangkun Meng Hao Liu Ruirui Hou Wan Lin Xiaoxu Zhang Xu Zhang Bei Cho Chai Feixiong Zhang Le Guo Shaoqi Yang Source Type: research
Corrigendum Role of the EZH2/miR ‑200 axis in STAT3‑mediated OSCC invasion
Int J Oncol. 2023 Jul;63(1):80. doi: 10.3892/ijo.2023.5528. Epub 2023 Jun 2.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, in Figs. 7A and 8A. apparently the same mouse had been featured to represent two different experimental groups, albeit displaying distinct fluorescence values. Moreover, following an independent investigation in the Editorial Office, an additional instance of probable data duplication was also noted, comparing between the 'SCC15 / si‑NC' cell migration image in Fig. 2D and the 'SCC15‑EV' migration assay image in Fig. 1C. After havin...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Wang Wenyu Guo Zhaoqing Li Yansheng Wu Chao Jing Yu Ren Minghui Zhao Lingping Kong Chao Zhang Jiabin Dong Yu Shuang Shanshan Sun Jinliang Chen Chuanqiang Wu Yu Qiao Xin Qu Xudong Wang Lun Zhang Rui Jin Xuan Zhou Source Type: research
m < sup > 6 < /sup > A ‑mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR‑552‑5p
Int J Oncol. 2023 Jul;63(1):81. doi: 10.3892/ijo.2023.5529. Epub 2023 Jun 2.ABSTRACTLong noncoding RNAs (lncRNAs) are a type of regulatory molecule with potential roles in the development of several different malignancies. However, the underlying mechanisms of lncRNAs in colorectal cancer (CRC) are incompletely understood. The present study investigated the molecular mechanism of LINC02038 in CRC. LINC02038 expression was decreased in CRC tissues compared to the para‑cancerous tissues and LINC02038 overexpression markedly reduced the proliferation, vitality, migration and invasive ability and greatly accelerated apoptosi...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Wenjun Liu Zilang Zhang Xitu Luo Kai Qian Baojun Huang Jianmin Liang Zhihao Ma Jianzhong Deng Chengyu Yang Source Type: research
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma
Int J Oncol. 2023 Jul;63(1):82. doi: 10.3892/ijo.2023.5530. Epub 2023 Jun 2.ABSTRACTCisplatin is the standard chemotherapeutic drug used for the treatment of esophageal squamous cell carcinoma (ESCC). Acquired cisplatin resistance is the primary obstacle to prolonging patient survival time. Here, the therapeutic effects of mitochondrial calcium uniporter (MCU) inhibition on tumor growth and cisplatin resistance in ESCC were assessed. MCU was stably overexpressed or knocked down in three ESCC cell lines and three cisplatin‑resistant ESCC cell lines. Then, proliferation, migration, and mitochondrial membrane potential (MMP...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Miao Xiaofei Wang Yafang Lai Ying Huang Hua Yin Xiangkun Meng Hao Liu Ruirui Hou Wan Lin Xiaoxu Zhang Xu Zhang Bei Cho Chai Feixiong Zhang Le Guo Shaoqi Yang Source Type: research
Corrigendum Role of the EZH2/miR ‑200 axis in STAT3‑mediated OSCC invasion
Int J Oncol. 2023 Jul;63(1):80. doi: 10.3892/ijo.2023.5528. Epub 2023 Jun 2.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, in Figs. 7A and 8A. apparently the same mouse had been featured to represent two different experimental groups, albeit displaying distinct fluorescence values. Moreover, following an independent investigation in the Editorial Office, an additional instance of probable data duplication was also noted, comparing between the 'SCC15 / si‑NC' cell migration image in Fig. 2D and the 'SCC15‑EV' migration assay image in Fig. 1C. After havin...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Wang Wenyu Guo Zhaoqing Li Yansheng Wu Chao Jing Yu Ren Minghui Zhao Lingping Kong Chao Zhang Jiabin Dong Yu Shuang Shanshan Sun Jinliang Chen Chuanqiang Wu Yu Qiao Xin Qu Xudong Wang Lun Zhang Rui Jin Xuan Zhou Source Type: research
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma
Int J Oncol. 2023 Jul;63(1):82. doi: 10.3892/ijo.2023.5530. Epub 2023 Jun 2.ABSTRACTCisplatin is the standard chemotherapeutic drug used for the treatment of esophageal squamous cell carcinoma (ESCC). Acquired cisplatin resistance is the primary obstacle to prolonging patient survival time. Here, the therapeutic effects of mitochondrial calcium uniporter (MCU) inhibition on tumor growth and cisplatin resistance in ESCC were assessed. MCU was stably overexpressed or knocked down in three ESCC cell lines and three cisplatin‑resistant ESCC cell lines. Then, proliferation, migration, and mitochondrial membrane potential (MMP...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Miao Xiaofei Wang Yafang Lai Ying Huang Hua Yin Xiangkun Meng Hao Liu Ruirui Hou Wan Lin Xiaoxu Zhang Xu Zhang Bei Cho Chai Feixiong Zhang Le Guo Shaoqi Yang Source Type: research
Corrigendum Role of the EZH2/miR ‑200 axis in STAT3‑mediated OSCC invasion
Int J Oncol. 2023 Jul;63(1):80. doi: 10.3892/ijo.2023.5528. Epub 2023 Jun 2.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that, in Figs. 7A and 8A. apparently the same mouse had been featured to represent two different experimental groups, albeit displaying distinct fluorescence values. Moreover, following an independent investigation in the Editorial Office, an additional instance of probable data duplication was also noted, comparing between the 'SCC15 / si‑NC' cell migration image in Fig. 2D and the 'SCC15‑EV' migration assay image in Fig. 1C. After havin...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Yu Wang Wenyu Guo Zhaoqing Li Yansheng Wu Chao Jing Yu Ren Minghui Zhao Lingping Kong Chao Zhang Jiabin Dong Yu Shuang Shanshan Sun Jinliang Chen Chuanqiang Wu Yu Qiao Xin Qu Xudong Wang Lun Zhang Rui Jin Xuan Zhou Source Type: research
m < sup > 6 < /sup > A ‑mediated LINC02038 inhibits colorectal cancer progression via regulation of the FAM172A/PI3K/AKT pathway via competitive binding with miR‑552‑5p
Int J Oncol. 2023 Jul;63(1):81. doi: 10.3892/ijo.2023.5529. Epub 2023 Jun 2.ABSTRACTLong noncoding RNAs (lncRNAs) are a type of regulatory molecule with potential roles in the development of several different malignancies. However, the underlying mechanisms of lncRNAs in colorectal cancer (CRC) are incompletely understood. The present study investigated the molecular mechanism of LINC02038 in CRC. LINC02038 expression was decreased in CRC tissues compared to the para‑cancerous tissues and LINC02038 overexpression markedly reduced the proliferation, vitality, migration and invasive ability and greatly accelerated apoptosi...
Source: International Journal of Oncology - June 2, 2023 Category: Cancer & Oncology Authors: Wenjun Liu Zilang Zhang Xitu Luo Kai Qian Baojun Huang Jianmin Liang Zhihao Ma Jianzhong Deng Chengyu Yang Source Type: research
