Filtered By:
Source: International Journal of Oncology
This page shows you your search results in order of date. This is page number 13.
Order by Relevance | Date
Total 2365 results found since Jan 2013.
Role of gasdermin family proteins in cancers (Review)
Int J Oncol. 2023 Sep;63(3):100. doi: 10.3892/ijo.2023.5548. Epub 2023 Jul 21.ABSTRACTThe gasdermin (GSDM) family comprises six proteins, including GSDMA‑GSDME and Pejvakin. Most of these proteins have a crucial role in inducing pyroptosis; in particular, GSDMD and GSDME are the most extensively studied proteins as the executioners of the pyroptosis process. Pyroptosis is a highly pro‑inflammatory form of programmed cell death and is closely associated with the incidence, development and prognosis of multiple cancer types. The present review focused on the current knowledge of the molecular mechanism of GSDM‑mediated...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Xin Yang Zhe Tang Source Type: research
Retracted Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
Int J Oncol. 2023 Sep;63(3):99. doi: 10.3892/ijo.2023.5547. Epub 2023 Jul 21.ABSTRACTFollowing the publication of the above article, a concerned reader has drawn to the Editor's attention that there were a number of apparently overlapping data panels shown in Fig. 4C and D on p. 2360 such that the data would have drawn from a smaller number of original sources, where the data panels were intended to show the results from differently performed experiments. Moreover, certain of the data shown in Figs. 2D, 3B, C and E and 4F contained data that were strikingly similar to data that have appeared in other publications written b...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Feng Tian Ding Ding Dandan Li Source Type: research
Role of gasdermin family proteins in cancers (Review)
Int J Oncol. 2023 Sep;63(3):100. doi: 10.3892/ijo.2023.5548. Epub 2023 Jul 21.ABSTRACTThe gasdermin (GSDM) family comprises six proteins, including GSDMA‑GSDME and Pejvakin. Most of these proteins have a crucial role in inducing pyroptosis; in particular, GSDMD and GSDME are the most extensively studied proteins as the executioners of the pyroptosis process. Pyroptosis is a highly pro‑inflammatory form of programmed cell death and is closely associated with the incidence, development and prognosis of multiple cancer types. The present review focused on the current knowledge of the molecular mechanism of GSDM‑mediated...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Xin Yang Zhe Tang Source Type: research
Retracted Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
Int J Oncol. 2023 Sep;63(3):99. doi: 10.3892/ijo.2023.5547. Epub 2023 Jul 21.ABSTRACTFollowing the publication of the above article, a concerned reader has drawn to the Editor's attention that there were a number of apparently overlapping data panels shown in Fig. 4C and D on p. 2360 such that the data would have drawn from a smaller number of original sources, where the data panels were intended to show the results from differently performed experiments. Moreover, certain of the data shown in Figs. 2D, 3B, C and E and 4F contained data that were strikingly similar to data that have appeared in other publications written b...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Feng Tian Ding Ding Dandan Li Source Type: research
Role of gasdermin family proteins in cancers (Review)
Int J Oncol. 2023 Sep;63(3):100. doi: 10.3892/ijo.2023.5548. Epub 2023 Jul 21.ABSTRACTThe gasdermin (GSDM) family comprises six proteins, including GSDMA‑GSDME and Pejvakin. Most of these proteins have a crucial role in inducing pyroptosis; in particular, GSDMD and GSDME are the most extensively studied proteins as the executioners of the pyroptosis process. Pyroptosis is a highly pro‑inflammatory form of programmed cell death and is closely associated with the incidence, development and prognosis of multiple cancer types. The present review focused on the current knowledge of the molecular mechanism of GSDM‑mediated...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Xin Yang Zhe Tang Source Type: research
Retracted Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells
Int J Oncol. 2023 Sep;63(3):99. doi: 10.3892/ijo.2023.5547. Epub 2023 Jul 21.ABSTRACTFollowing the publication of the above article, a concerned reader has drawn to the Editor's attention that there were a number of apparently overlapping data panels shown in Fig. 4C and D on p. 2360 such that the data would have drawn from a smaller number of original sources, where the data panels were intended to show the results from differently performed experiments. Moreover, certain of the data shown in Figs. 2D, 3B, C and E and 4F contained data that were strikingly similar to data that have appeared in other publications written b...
Source: International Journal of Oncology - July 21, 2023 Category: Cancer & Oncology Authors: Feng Tian Ding Ding Dandan Li Source Type: research
circRPS19 affects HK2 ‑mediated aerobic glycolysis and cell viability via the miR‑125a‑5p/USP7 pathway in gastric cancer
Int J Oncol. 2023 Aug;63(2):98. doi: 10.3892/ijo.2023.5546. Epub 2023 Jul 14.ABSTRACTDespite advances in diagnosis and treatment, gastric cancer (GC) remains a refractory disease, which limits overall survival. Therefore, it is key to identify novel targets to develop more effective and precise treatment. Circular RNAs (circRNAs) serve essential roles in the process of various human cancers. Through analyzing GSE83521 dataset, the present study identified a novel circRNA derived from ribosomal protein S19 (circRPS19), which was considered a potential treatment target for GC. Results of RT‑qPCR indicated that circRPS19 wa...
Source: International Journal of Oncology - July 14, 2023 Category: Cancer & Oncology Authors: Xia Zheng Jie Shao Jun Qian Shenlin Liu Source Type: research
Corrigendum Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF- β-driven progression of pancreatic cancer
Int J Oncol. 2023 Aug;63(2):95. doi: 10.3892/ijo.2023.5543. Epub 2023 Jul 7.ABSTRACTSubsequently to the publication of the above article, an interested reader drew to the authors' attention that two pairs of the culture plate images in Fig. 4A-C on p. 60 appeared to be the same, although the images were shown in different orientations; moreover, the 'NC/0 and DEX+miR132' and 'DEX and miR132' pairings of images in the scratch-wound assay experiments shown in Fig. 4B also appeared to be overlapping, such that these were apparently derived from the same original source where the results of differently performed experiments we...
Source: International Journal of Oncology - July 7, 2023 Category: Cancer & Oncology Authors: Alia Abukiwan Clifford C Nwaeburu Nathalie Bauer Zhefu Zhao Li Liu Jury Gladkich Wolfgang Gross Axel Benner Oliver Strobel J örg Fellenberg Ingrid Herr Source Type: research
Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF ‑κB in lung cancer
Int J Oncol. 2023 Aug;63(2):96. doi: 10.3892/ijo.2023.5544. Epub 2023 Jul 7.ABSTRACTThe pathogenesis mechanism of lung cancer is very complex, with high incidence and mortality. Serpin family A member 3 (SERPINA3) expression levels were reduced in the sera of patients with lung cancer and may be a candidate diagnostic and prognostic survival biomarker in lung cancer, as previously reported. However, the detailed biological functions of SERPINA3 in the pathogenesis of lung cancer remain unknown. In the present study, it was aimed to explore the effects of SERPINA3 on the occurrence of lung cancer. SERPINA3 expression was as...
Source: International Journal of Oncology - July 7, 2023 Category: Cancer & Oncology Authors: Yanxia Jin Yueyang Zhang Ankang Huang Ying Chen Jinsong Wang Na Liu Xianping Wang Yongsheng Gong Weidong Wang Jicheng Pan Source Type: research
Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review)
Int J Oncol. 2023 Aug;63(2):97. doi: 10.3892/ijo.2023.5545. Epub 2023 Jul 7.ABSTRACTNasopharyngeal carcinoma (NPC) is an epithelial tumor located in the nasopharynx and is highly associated with Epstein‑Barr virus (EBV) infection. Although radiotherapy alone can cure ~90% of patients with early‑stage disease, >70% of patients with NPC have locoregionally advanced or metastatic disease at the first diagnosis due to the insidious and aggressive nature of NPC. After comprehensive radiochemotherapy, 20‑30% of patients with advanced NPC still fail treatment, mainly due to recurrence and/or metastasis (R/M). Conventiona...
Source: International Journal of Oncology - July 7, 2023 Category: Cancer & Oncology Authors: Huageng Huang Yuyi Yao Xinyi Deng Zongyao Huang Yungchang Chen Zhao Wang Huangming Hong He Huang Tongyu Lin Source Type: research
