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Source: Journal of Cellular Physiology
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Total 116 results found since Jan 2013.
The Association between p38 MAPK‐Mediated TNF‐α/TNFR2 Up‐Regulation and 2‐(4‐Aminophenyl)‐7‐Methoxybenzothiazole‐Induced Apoptosis in Human Leukemia U937 Cells
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - June 8, 2015 Category: Cytology Authors: Chia‐Hui Huang, Ying‐Jung Chen, Tzu‐Yu Chao, Wen‐Hsin Liu, Jung‐Jung Changchien, Wan‐Ping Hu, Long‐Sen Chang Tags: Original Research Article Source Type: research
S100A8, an Oocyte‐Specific Chemokine, Directs the Migration of Ovarian Somatic Cells During Mice Primordial Follicle Assembly
This study was performed to address this issue. Firstly, in an in vitro reconstruction system, dispersed ovarian cells from murine fetal ovaries at 19.0 days post coitum (dpc) reassembled into follicle‐like structures, independent of the physical distance between the cells, implying that either oocytes or ovarian somatic cells (OSCs) were motile. We then carried out a series of transwell assay experiments, and determined that it was in fact 19.0 dpc OSCs (as opposed to oocytes), which exhibited a significant chemotactic response to both fetal bovine serum and oocytes themselves. We observed that S100A8, a multi‐functio...
Source: Journal of Cellular Physiology - May 6, 2015 Category: Cytology Authors: Zhen Teng, Chao Wang, Yijing Wang, Hua Zhang, Kun Huang, Xi Xiang, Wanbao Niu, Lizhao Feng, Lihua Zhao, Hao Yan, Guoliang Xia Tags: Original Research Article Source Type: research
c‐Src‐dependent transactivation of EGFR mediates CORM‐2‐induced HO‐1 expression in human tracheal smooth muscle cells
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Source: Journal of Cellular Physiology - April 29, 2015 Category: Cytology Authors: Chuen‐Mao Yang, Chih‐Chung Lin, I‐Ta Lee, Chih‐Kai Hsu, Yu‐Chen Tai, Hsi‐Lung Hsieh, Pei‐Ling Chi, Andli‐Der Hsiao Tags: Original Research Article Source Type: research
TGF‐Beta Suppresses Ift88 Expression in Chondrocytic ATDC5 Cells
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Source: Journal of Cellular Physiology - April 1, 2015 Category: Cytology Authors: Makiri Kawasaki, Yoichi Ezura, Tadayoshi Hayata, Takuya Notomi, Yayoi Izu, Masaki Noda Tags: Original Research Article Source Type: research
The Role of Maternal Gestational Diabetes in Inducing Fetal Endothelial Dysfunction
This study examines the effect of maternal diabetes on fetal endothelial function and gene expression under physiological glucose conditions (5mM). Human umbilical vein endothelial cell (HUVEC) isolated from diabetic mothers (d.HUVEC) grew more slowly than HUVEC isolated from healthy mothers (c.HUVEC) and had delayed doubling time despite increased levels of total vascular endothelial growth factor (VEGF) expression and protein production as determined by real time PCR and ELISA respectively. Using western blot, the levels of antiproliferative VEGF165b isoform were increased in d.HUVEC relative to c.HUVEC. Successful VEGF1...
Source: Journal of Cellular Physiology - March 24, 2015 Category: Cytology Authors: Samar A Sultan, Wanting Liu, Yonghong Peng, W. Roberts, Donald Whitelaw, Anne M Graham Tags: Original Research Article Source Type: research
Gap Junctions Enhance the Antiproliferative Effect of MicroRNA‐124‐3p in Glioblastoma Cells
In conclusion, our results indicate that the “bystander” effects of functional gap junctions composed of connexin 43 enhance the antitumor effect of miR‐124‐3p in glioblastoma cells by transferring miR‐124‐3p to adjacent cells, thereby enhancing G0/G1 cell cycle arrest. These observations provide a new guiding strategy for the clinical application of miRNA therapy in tumor treatment. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - March 9, 2015 Category: Cytology Authors: Suzhi Zhang, Qin Wang, Lucy Liu, Xiaoting Hong, Yuan Zhang, Liang Tao Tags: Original Research Article Source Type: research
Cross‐Talk Between VEGF and BMP‐6 Pathways Accelerates Osteogenic Differentiation of Human Adipose‐Derived Stem Cells
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Source: Journal of Cellular Physiology - March 9, 2015 Category: Cytology Authors: Ching‐Ju Li, Vedavathi Madhu, Gary Balian, Abhijit S. Dighe, Quanjun Cui Tags: Original Research Article Source Type: research
Depletion of Amyloid Precursor Protein (APP) Causes G0 Arrest in Non‐Small Cell Lung Cancer (NSCLC) Cells
We recently reported that Amyloid Precursor Protein (APP) regulates global protein synthesis in a variety of human dividing cells, including non‐small cell lung cancer (NSCLC) cells. More specifically, APP depletion causes an increase of both cap‐ and IRES‐dependent translation. Since growth and proliferation are tightly coupled processes, here, we asked what effects artificial downregulation of APP could have elicited in NSCLC cells proliferation. APP depletion caused a G0/G1 arrest through destabilization of the cyclin‐C protein and reduced pRb phosphorylation at residues Ser802/811. siRNA to cyclin‐C mirrored ...
Source: Journal of Cellular Physiology - February 25, 2015 Category: Cytology Authors: Anna Sobol, Paola Galluzzo, Megan J. Weber, Sara Alani, Maurizio Bocchetta Tags: Original Research Article Source Type: research
Phospholipase C Epsilon (PLCε) Induced TRPC6 Activation: A Common but Redundant Mechanism in Primary Podocytes
In eukaryotic cells, activation of phospholipase C (PLC)‐coupled membrane receptors by hormones leads to an increase in the intracellular Ca2+ concentration [Ca2+]i. Catalytic activity of PLCs results in the hydrolysis of phosphatidylinositol 4,5‐bisphosphate to generate inositol 1,4,5‐trisphosphate (IP3) and diacylglycerol (DAG) which opens DAG‐sensitive classical transient receptor channels 3, 6, and 7 (TRPC3/6/7), initiating Ca2+ influx from the extracellular space. Patients with focal segmental glomerulosclerosis (FSGS) express gain‐of‐function mutants of TRPC6, while others carry loss‐of‐function mutan...
Source: Journal of Cellular Physiology - February 25, 2015 Category: Cytology Authors: Hermann Kalwa, Ursula Storch, Jana Demleitner, Susanne Fiedler, Tim Mayer, Martina Kannler, Meike Fahlbusch, Holger Barth, Alan Smrcka, Friedhelm Hildebrandt, Thomas Gudermann, Alexander Dietrich Tags: Original Research Article Source Type: research
Wnt5a Induces Collagen Production by Human Periodontal Ligament Cells through TGFβ1‐mediated Upregulation of Periostin Expression
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Source: Journal of Cellular Physiology - February 5, 2015 Category: Cytology Authors: Daigaku Hasegawa, Naohisa Wada, Hidefumi Maeda, Shinichiro Yoshida, Hiromi Mitarai, Atsushi Tomokiyo, Satoshi Monnouchi, Sayuri Hamano, Asuka Yuda, Akifumi Akamine Tags: Original Research Article Source Type: research
Shear Stress Modulates Resistin‐Induced CC Chemokine Ligand 19 Expression in Human Aortic Endothelial Cells
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Source: Journal of Cellular Physiology - February 5, 2015 Category: Cytology Authors: Hong‐Ren Yu, Mao‐Ling Sung, Hsing‐Chun Kuo, Chi‐Hui Lin, Cheng‐Nan Chen Tags: Original Research Article Source Type: research
Functional role of the KCa3.1 potassium channel in synovial fibroblasts from rheumatoid arthritis patients
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Source: Journal of Cellular Physiology - December 29, 2014 Category: Cytology Authors: Kristin Friebel, Roland Schönherr, Raimund W. Kinne, Elke Kunisch Tags: Original Research Article Source Type: research
Chemokine (C‐C motif) ligand 5 is involved in tumor‐associated dendritic cell‐mediated colon cancer progression through non‐coding RNA MALAT‐1
In conclusion, the inhibition of CCL5 or CCL5‐related signaling may be an attractive therapeutic target in colon cancer patients. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - December 24, 2014 Category: Cytology Authors: Jung‐Yu Kan, Deng‐Chyang Wu, Fang‐Jung Yu, Cheng‐Ying Wu, Ya‐Wen Ho, Yen‐Jung Chiu, Shu‐Fang Jian, Jen‐Yu Hung, Jaw‐Yuan Wang, Po‐Lin Kuo Tags: Original Research Article Source Type: research
Wild‐type and Specific Mutant Androgen Receptor Mediates Transcription via 17β‐Estradiol in Sex Hormone‐sensitive Cancer Cells
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Source: Journal of Cellular Physiology - December 23, 2014 Category: Cytology Authors: Takao Susa, Reina Ikaga, Takashi Kajitani, Masayoshi Iizuka, Hiroko Okinaga, Mimi Tamamori‐Adachi, Tomoki Okazaki Tags: Original Research Article Source Type: research
Phospholipase C epsilon‐induced TRPC6 activation: A common but redundant mechanism in primary podocytes
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - December 18, 2014 Category: Cytology Authors: Hermann Kalwa, Ursula Storch, Jana Demleitner, Susanne Fiedler, Tim Mayer, Martina Kannler, Meike Fahlbusch, Holger Barth, Alan Smrcka, Friedhelm Hildebrandt, Thomas Gudermann, Alexander Dietrich Tags: Original Research Article Source Type: research
