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Cancer: Prostate Cancer
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Total 879 results found since Jan 2013.
Identification and validation of hub genes in prostate cancer progression based on weighted gene co-expression network analysis
CONCLUSION: We identified 3 hub genes related with the occurrence (BDH1, PAK4 and EXTL3) and another 3 with metastasis of prostate cancer (NKTR, CTBP2 and HNRNPA2B1) using WGCNA, which provides a new approach for studying the regulatory mechanisms of prostate cancer.PMID:34916188 | PMC:PMC8685695 | DOI:10.12122/j.issn.1673-4254.2021.11.06
Source: Journal of Southern Medical University - December 17, 2021 Category: Universities & Medical Training Authors: H Zhang N Chen X Wang B Gao M Ling G Chen Z Wu Y Li W Zhong B Pan Source Type: research
LncRNA LINC00184 promotes docetaxel resistance and immune escape via miR-105-5p/PD-L1 axis in prostate cancer
CONCLUSIONS: LINC00184 promoted docetaxel resistance and immune escape in prostate cancer cells by adsorption of miR-105-5p, resulted in upregulation of the expression of PD-L1. LINC00184 could possibly be considered as a potential target for treatment in prostate cancer patients with docetaxel-resistance.PMID:34896914 | DOI:10.1016/j.imbio.2021.152163
Source: Immunobiology - December 13, 2021 Category: Allergy & Immunology Authors: Wei Zhang Jun Xin Jinjin Lai Wenbin Zhang Source Type: research
Ratio of the expression levels of androgen receptor splice variant 7 to androgen receptor in castration refractory prostate cancer
Oncol Lett. 2021 Dec;22(6):831. doi: 10.3892/ol.2021.13092. Epub 2021 Oct 13.ABSTRACTIn clinical samples, the expression of androgen receptor (AR) and of AR splice variant 7 (AR-V7) is higher in castration-resistant prostate cancer (CRPC) compared with that in hormone-sensitive prostate cancer (PCa). However, there are only a few reports on the ratio of the expression levels of AR-V7 to AR (AR-V7/AR) in prostate tissue. The present study evaluated AR-V7/AR expression in various types of human prostate tissues and CRPC cells. Pretreatment prostate tissue samples from patients with benign prostatic hyperplasia (BPH; n=18), G...
Source: Oncology Letters - October 25, 2021 Category: Cancer & Oncology Authors: Yoshitaka Sekine Hiroshi Nakayama Yoshiyuki Miyazawa Seiji Arai Hidekazu Koike Hiroshi Matsui Yasuhiro Shibata Kazuto Ito Kazuhiro Suzuki Source Type: research
