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Cancer: Ovarian Cancer
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Total 485 results found since Jan 2013.
Expression of circ-PHC3 enhances ovarian cancer progression via regulation of the miR-497-5p/SOX9 pathway
CONCLUSION: Taken together, our findings suggest that circ-PHC3 enhances OC progression through functioning as an miR-497-5p sponge to promote SOX9 expression, supporting its potential as a promising candidate target for OC therapy.PMID:37468993 | DOI:10.1186/s13048-023-01170-w
Source: Cell Research - July 19, 2023 Category: Cytology Authors: Hongxia Wang Suwei Lan Lingxiang Wang Jingyun Zhao Xinzhuan Jia Jie Xu Guangyu Sun Leilei Liu Shan Gong Na Wang Baoen Shan Fenghua Zhang Zhengmao Zhang Source Type: research
NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
This study provides evidence that NPFF stimulates EOC cell invasion by upregulating MMP-9 expression through the NPFFR2-mediated ERK1/2 signaling pathway.PMID:37392963 | DOI:10.1016/j.yexcr.2023.113693
Source: Cell Research - July 1, 2023 Category: Cytology Authors: Ze Wu Qiongqiong Jia Boqun Liu Lanlan Fang Peter C K Leung Jung-Chien Cheng Source Type: research
Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12
In conclusion, the transdermal peptide PKU12 is potentially a good candidate for a siRNA delivery vehicle for the treatment of cervical cancer.PMID:37350944 | PMC:PMC10282752 | DOI:10.3389/fonc.2023.1175958
Source: Cancer Control - June 23, 2023 Category: Cancer & Oncology Authors: Yan Deng Yi Song Quan Du Chi Chiu Wang Hu Li Yi Sui Yuying Zhang Tao Tang Source Type: research
MiR-5590-3p inhibits the proliferation and invasion of ovarian cancer cells through mediating the Wnt/ β-catenin signaling pathway by targeting TNIK
In conclusion, miR-5590-3p may function as a cancer suppressor gene in OC progression through the Wnt/β-catenin signaling by transcriptionally suppressing TNIK expression, which provides a potential therapeutic approach for ovarian cancer treatment.PMID:37318197 | DOI:10.14670/HH-18-636
Source: Histology and Histopathology - June 15, 2023 Category: Cytology Authors: Xiaoling Wu Youwen Zhong Hua Zhang Mu Li Source Type: research
Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12
In conclusion, the transdermal peptide PKU12 is potentially a good candidate for a siRNA delivery vehicle for the treatment of cervical cancer.
Source: Frontiers in Oncology - June 7, 2023 Category: Cancer & Oncology Source Type: research
SPTBN2 regulates endometroid ovarian cancer cell proliferation, invasion and migration via ITGB4 ‑mediated focal adhesion and ECM receptor signalling pathway
Exp Ther Med. 2023 Apr 24;25(6):277. doi: 10.3892/etm.2023.11977. eCollection 2023 Jun.ABSTRACTOvarian cancer is as a major contributor to gynaecologic death globally. The present study aimed to investigate the regulatory role of spectrin β non-erythrocytic 2 gene (SPTBN2) in endometroid ovarian cancer and its mechanism of action. According to the Gene Expression Profiling Interactive Analysis (GEPIA) database, SPTBN2 expression is elevated in ovarian cancer tissues and higher SPTBN2 expression indicated a worse prognosis. The present study assessed SPTBN2 mRNA and protein expression levels by reverse transcription-quanti...
Source: Experimental and Therapeutic Medicine - May 19, 2023 Category: General Medicine Authors: La Yang Yuanyuan Gu Source Type: research
