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Total 3372 results found since Jan 2013.
Knockdown of LPCAT1 Repressed Hepatocellular Carcinoma Growth and Invasion by Targeting S100A11
CONCLUSION: LPCAT1 promoted the growth, invasion and migration of HCC cells by regulating S100A11 and Snail. Therefore, LPCAT1 may serve as a potential molecular target for the diagnosis and treatment of HCC.PMID:37094849
Source: Annals of Clinical and Laboratory Science - April 24, 2023 Category: Laboratory Medicine Authors: Qigang Sun Cexiong Fu Jun Liu Shibing Li Jinfang Zheng Source Type: research
ROS and DRP1 interactions accelerate the mitochondrial injury induced by polystyrene nanoplastics in human liver HepG2 cells
Chem Biol Interact. 2023 Apr 19:110502. doi: 10.1016/j.cbi.2023.110502. Online ahead of print.ABSTRACTMicroplastics have become a serious environmental pollutant and subsequently have harmful effects on human health. Thus, the impacts of microplastics on human cells need to be explored. In the present study, the cytotoxic effects at the subcellular-organelle levels to polystyrene nanoplastics (PS-NPs, diameter 21.5 ± 2.7 nm) were investigated in the human hepatocellular carcinoma (HepG2) cell line. The cell viability exposed to PS-NPs at the concentrations of 6.25, 12.5, 25 and 50 μg/mL for 24 h diminished in a concentra...
Source: Chemico-Biological Interactions - April 21, 2023 Category: Molecular Biology Authors: Yunjing Li Menghao Guo Shuyan Niu Mengting Shang Xiaoru Chang Zuoyi Sun Rui Zhang Xin Shen Yuying Xue Source Type: research
CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells
J Cell Mol Med. 2023 Apr 21. doi: 10.1111/jcmm.17750. Online ahead of print.ABSTRACTHuman oral squamous cell carcinoma (OSCC) has been associated with a relatively low survival rate over the years and is characterized by a poor prognosis. C-X3-C motif chemokine ligand 1 (CX3CL1) has been involved in advanced migratory cells. Overexpressed CX3CL1 promotes several cellular responses related to cancer metastasis, including cell movement, migration and invasion in tumour cells. However, CX3CL1 controls the migration ability, and its molecular mechanism in OSCC remains unknown. The present study confirmed that CX3CL1 increased ...
Source: J Cell Mol Med - April 21, 2023 Category: Molecular Biology Authors: Chia-Yu Wu Pei-Wen Peng Ting-Yi Renn Chia-Jung Lee Tsung-Ming Chang Augusta I-Chin Wei Ju-Fang Liu Source Type: research
ROS and DRP1 interactions accelerate the mitochondrial injury induced by polystyrene nanoplastics in human liver HepG2 cells
Chem Biol Interact. 2023 Apr 19:110502. doi: 10.1016/j.cbi.2023.110502. Online ahead of print.ABSTRACTMicroplastics have become a serious environmental pollutant and subsequently have harmful effects on human health. Thus, the impacts of microplastics on human cells need to be explored. In the present study, the cytotoxic effects at the subcellular-organelle levels to polystyrene nanoplastics (PS-NPs, diameter 21.5 ± 2.7 nm) were investigated in the human hepatocellular carcinoma (HepG2) cell line. The cell viability exposed to PS-NPs at the concentrations of 6.25, 12.5, 25 and 50 μg/mL for 24 h diminished in a concentra...
Source: Chemico-Biological Interactions - April 19, 2023 Category: Molecular Biology Authors: Yunjing Li Menghao Guo Shuyan Niu Mengting Shang Xiaoru Chang Zuoyi Sun Rui Zhang Xin Shen Yuying Xue Source Type: research
