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Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

miR-200b-mediated reversion of a spectrum of epithelial to mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas
CONCLUSIONS: In summary, RDEB-SCCs exist in different EMT states and the level of miR-200b is indicative of how far an RDEB-SCC has gone down the EMT path. Moreover, reintroduction of miR-200b significantly reduced mesenchymal features.PMID:37681509 | DOI:10.1093/bjd/ljad335
Source: The British Journal of Dermatology - September 8, 2023 Category: Dermatology Authors: Julia Illmer Roland Zauner Josefina Pi ñón Hofbauer Monika Wimmer Stefanie Gruner Michael Ablinger Johannes Bischof Sonja Dorfer Stefan Hainzl Vanessa Tober Shir Bergson Ofer Sarig Liat Samuelov Christina Guttmann-Gruber Ruby Shalom-Feuerstein Eli Sprec Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research

Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy
CONCLUSION: PXC could inhibit the proliferation and invasion of TNBC both and , and exerted its anti-metastatic effect by regulating cadherin turnover, Furthermore, it sensitized the TNBC cells to radiotherapy. The data supported further development of PXC as an adjuvant-therapy agent for TNBC.PMID:37679977 | PMC:PMC10465830 | DOI:10.19852/j.cnki.jtcm.20221121.003
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Tang Wenjuan H U Yu Zhu Man Dong Mingzhi Liu Tieming Sarwar Ammar Zhan Yingzhuan Zhang Yanmin Source Type: research

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway
CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Yang Xiaohui Wang Jian Cheng Li Zhang Yuxi Huang Jianlin Liu Minghua Source Type: research