Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway

CONCLUSIONS: ACAK can partly inhibit the activity of EMT and matrix metallopeptidases by down-regulating the downstream proteins of PI3K/Akt/mTOR signal pathway, thus inhibiting the ability of migration and invasion of pancreatic cancer.PMID:37679975 | PMC:PMC10465845 | DOI:10.19852/j.cnki.jtcm.20230802.004
Source: Journal of Traditional Chinese Medicine - Category: Complementary Medicine Authors: Source Type: research