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Vaccination: Varicella-Zoster Virus Vaccine

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Total 265 results found since Jan 2013.

Natural History of Herpes Zoster in the Placebo Groups of Three Randomized Phase  III Clinical Trials
ConclusionThe incidence and burden of HZ is high in immunocompetent adults aged ≥ 50 YOA and even more so in HSCT recipients aged ≥ 18 YOA.Graphical Abstract
Source: Infectious Diseases and Therapy - November 23, 2022 Category: Infectious Diseases Source Type: research

Headache After Vaccination: An Update on Recent Clinical Trials and Real-World Reporting
Curr Pain Headache Rep. 2022 Nov 23. doi: 10.1007/s11916-022-01094-y. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The aim of this review is to characterize headache as a vaccine adverse event (VAE) in clinical trials.RECENT FINDINGS: Of the recent phase III vaccine RCTs (non-COVID-19), 53 studies reported on headache (13 infectious agents). The median rate (interquartile range) of headache was 15.6% (IQR: 9.6-37.6%). Of these, 24.5% of the RCTs reported headache greater in the vaccine group compared to the placebo/control group. In the herpes zoster vaccination trials, headache was more common in all active groups: me...
Source: Herpes - November 23, 2022 Category: Infectious Diseases Authors: Kimberly N Garces Alexandra N Cocores Peter J Goadsby Teshamae S Monteith Source Type: research

Quality of life and risk factors in patients with herpes zoster
Conclusions: More than half of the patients with HZ had moderate to severe pain in the past 24 hours, which had a serious negative impact on the physical and mental health of the patients. Elderly patients, acute patients and patients with complications had lower health utility values and worse health status. We suggest that eligible people be vaccinated with HZ vaccine as soon as possible.PMID:36372770 | DOI:10.3760/cma.j.cn112137-20220627-01416
Source: Herpes - November 13, 2022 Category: Infectious Diseases Authors: Q Zhang Z S Huang Q Q Hu W Qin L L Liang F Cui Y Wang F Pan X L Liu L Tang C Ma Z D Yin F Z Wang Source Type: research

An Unusual Case of Arm Pain in a Young Soccer Player: Herpes Zoster in the Pediatric Athlete
Curr Sports Med Rep. 2022 Nov 1;21(11):386-390. doi: 10.1249/JSR.0000000000001005.ABSTRACTHerpes zoster (HZ), shingles, is caused by the varicella-zoster virus (VZV). HZ develops as a reactivation of latent VZV and is characterized by a painful, vesicular rash typically manifesting in a dermatomal distribution on the arms, trunk or face. HZ occurs in individuals who had primary VZV disease (chickenpox) as a child or in those who have received live, attenuated VZV vaccine. HZ is common in the elderly and the immunocompromised, with age being the single greatest risk factor. The incidence of HZ in children is 74/100,000 pers...
Source: Herpes - November 7, 2022 Category: Infectious Diseases Authors: James MacDonald Joy Mosser-Goldfarb Cristina Tomatis Souverbielle Steven Cuff Source Type: research