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Chip for Investigation of Coronavirus Intestinal Infection
This study demonstrates that we can explore complex interactions between cells, pathogens, and drugs in the human intestine using our Intestine Chip as a preclinical model,” said Don Ingber, a researcher involved in the study, via a press release. ...
Source: Medgadget - November 10, 2021 Category: Medical Devices Authors: Conn Hastings Tags: GI Medicine Public Health Source Type: blogs

Combining Virtual Reality and Behavioral Health to Promote Pain Resiliency: Analysis of a Novel BioPsychoSocial Modality for Solving Pain in the Workplace
ConclusionsThe Harvard MedTech Vx Therapy appears to be an effective tool in the treatment of pain and the psycho-social issues associated with pain. This translates into a greater degree of pain resiliency and an overall improvement in general wellness and improved workplace functionality.
Source: Pain and Therapy - October 16, 2021 Category: Anesthesiology Source Type: research

Pathways: The Anesthesia Issue
Cover of Pathways student magazine. NIGMS and Scholastic bring you Pathways: The Anesthesia Issue, which explores pain and the science behind anesthesia—the medical treatment that prevents patients from feeling pain during surgery and other procedures. Without anesthesia, many life-saving medical procedures would be impossible. Pathways, designed for students in grades 6 through 12, aims to build awareness of basic biomedical science and its importance to health, while inspiring careers in research. All materials in the collection are available online and are free for parents, educators, and students nationwide. ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 14, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Injury and Illness Anesthesiology Pain Source Type: blogs

Can Cannabis Help Your Gut?
When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - September 23, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Source Type: news

Johnson & Johnson Announces Real-World Evidence and Phase 3 Data Confirming Strong and Long-Lasting Protection of Single-Shot COVID-19 Vaccine in the U.S.
This study compared approximately 390,000 people who received the Company’s single-shot COVID-19 vaccine versus approximately 1.52 million unvaccinated people matched on age, sex, time, three-digit zip code, and comorbidities and predictors for COVID-19 infection severity.This study is a longitudinal cohort design, using robust propensity matching methods to create a comparator cohort to assess real-world VE. All analyses were performed using the Aetion Evidence Platform, which is a scientifically validated software that is also used by regulators, payers, and health technology assessment bodies to assess the safety, eff...
Source: Johnson and Johnson - September 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Morning Distort
By MARTIN A. SAMUELS A 35 year old woman complains of weakness of the right side of her face and pain behind the right ear.  She lives in an urban environment and denies any recent illnesses.  She is not vaccinated against COVID-19 but is COVID negative.  What do you think, I was asked at our Morning Report?  Well, I said, it sounds like a straightforward Bell palsy.  The pain around the ear suggests swelling of the VIIth cranial nerve in the facial canal and the stylomastoid foramen, a very common historical point, I opined; so much so that its absence would make me doubt the diagnosis and m...
Source: The Health Care Blog - August 12, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Martin A. Samuels morning report neurology Source Type: blogs

Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury
ConclusionsPoor quality of sleep as well as symptoms suggestive of anxiety and depression were more common in patients with persistent PTH than healthy controls. Clinicians should screen patients with persistent PTH for these comorbidities and develop treatment plans that account for their presence.
Source: The Journal of Headache and Pain - July 26, 2021 Category: Neurology Source Type: research

Correlation Between Pharmacy Students' Implicit Bias Scores, Explicit Bias Scores, and Responses to Clinical Cases
Conclusion. Evidence of slight to moderate negative implicit bias and slight negative explicit bias towards Black patients does exist for pharmacy students. Future studies that include a more representative student population and heighten the stakes of the clinical scenario should be done to investigate a possible correlation between bias and clinical behaviors.PMID:34301558 | DOI:10.5688/ajpe8587
Source: American Journal of Pharmaceutical Education - July 24, 2021 Category: Universities & Medical Training Authors: Jennifer Santee Kylie Barnes Nancy Borja-Hart An-Lin Cheng Juanita Draime Akesha Edwards Nkem Nonyel Mark Sawkin Source Type: research

We Used to Have a Lyme Disease Vaccine. Are We Ready to Bring One Back?
At my animal hospital in upstate New York, an epicenter of the U.S. tick epidemic, my dog Fawn lets out a whimper as the veterinarian injects her with her annual Lyme disease shot. I roll my eyes. She doesn’t know how good she has it. The injection means that if a tick bites her (and in rural New York, a tick always does), the creepy crawly will feast on dog blood that’s been supercharged with a Lyme bacteria-killing substance, and Lyme disease won’t be transmitted to Fawn. I wish I could be shot up with that superpower. Currently, there is no human vaccine for Lyme disease—even though more than two...
Source: TIME: Health - June 17, 2021 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized Disease feature Source Type: news

An Abrupt Change in Mental Status
Dr. Hazar Khidir: Today's case is that of a 35-year-old woman brought to the Emergency Department (ED) for evaluation of altered mental status. She was brought in by her partner, who provided the entirety of the initial history, given her altered mental status. Per her partner, she did not have any preceding medical history and was a full-time graduate student. Her symptoms started 5 days prior to presentation when she complained of muscle pain, a mild headache, and nausea. Later that evening, she also developed a fever to 38.3 °C (101°F).
Source: The Journal of Emergency Medicine - June 11, 2021 Category: Emergency Medicine Authors: Hazar Khidir, Benjamin A. White, Adaira Landry, Amy A. Cameron, Kathleen Wittels, Susan R. Wilcox Tags: Case Presentations of the Harvard Emergency Medicine Residencies Source Type: research

Genetic base editing treats sickle cell disease in mice
(Broad Institute of MIT and Harvard) Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team led by Broad Institute of MIT and Harvard and St. Jude Children's Research Hospital has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD.
Source: EurekAlert! - Medicine and Health - June 3, 2021 Category: International Medicine & Public Health Source Type: news

Can Music Technologies Help The Mental Health Pandemic?
We tend to think that we know how our brain works. We believe that art and creativity (thus, music, too) belong to the right hemisphere of it and math, logic, linear thinking and facts to the left. Interestingly, as Daniel J. Levitin explains in his book, “This Is Your Brain on Music”, music is processed throughout the brain. Maybe that is why music has been elemental throughout human history: it can connect people with each other.  So when the first lockdown began worldwide, we all started to look for things to do at home, to eliminate the feeling of disconnectedness. One choice, watching movies, was obvious ...
Source: The Medical Futurist - May 13, 2021 Category: Information Technology Authors: Judit Kuszkó Tags: Covid-19 Lifestyle medicine E-Patients Future of Medicine music mental health mental wellbeing music therapy covid19 lockdown quarantine Daniel J. Levitin Kiminobu Sugaya Ayako Yonetani Dr Janos Kollar Will Henshall Focus@W Source Type: blogs

Wound Odor: The View from Ancient Greece
Philoctetes fanning his malodorous foot wound with the wing of a bird in a painting by Jen-Germain Drouais, 1788. The fascinating history of wound care dates back to the earliest human cultures, where prehistoric bones and cave paintings left hints of wound-healing knowledge.  A major problem associated with wounds is odor, a phenomenon recognized for millennia.  In today’s practice, when examining and documenting wounds, the standard of care requires noting the presence of odor.   Odor associated with a wound can result from necrotic tissue and metabolic by-products of certain bacteria.  Pseudomonas, for example, c...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - May 10, 2021 Category: Geriatrics Authors: Jeffrey M Levine Tags: Featured Medical Articles Pressure Injuries & Wound Care medical history medicine and art pressure sore pressure sores pressure ulcer pressure ulcers wound healing Source Type: blogs