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Vaccination: Vaccines
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Africa: Refusal to Waive IP Rights for Covid-19 Vaccines Violates Human Rights - Experts
[UN News] UN rights experts called on States in the global North on Thursday to forgo intellectual property rights on COVID-19 vaccines and treatments in the name of human rights.
Source: AllAfrica News: Health and Medicine - September 1, 2023 Category: African Health Tags: Africa Coronavirus External Relations Health and Medicine Human Rights International Organizations and Africa Source Type: news
Correction
Bellusci L, Zahra FT, Hopkins DE, et al. Durability of Immunity Is Low Against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron BA.1, BA.2, and BA.3 Variants After Second and Third Vaccinations in Children and Young Adults With Inflammatory Bowel Disease Receiving Biologics. Gastroenterology 2022;163:1672–1675.
Source: Gastroenterology - September 1, 2023 Category: Gastroenterology Tags: Correction Source Type: research
mRNA-Based Nanomedicine: A New Strategy for Treating Infectious Diseases and Beyond
AbstractMessenger RNA (mRNA) has emerged as a new therapeutic agent for the prevention and treatment of a wide range of diseases. The recent achievement of the two lipid nanoparticle-mRNA vaccines developed by Moderna and Pfizer-BioNTech against coronavirus 2019 (COVID-19) disease in record time highlights the huge potential of mRNA technology and reshaping the landscape of vaccine deve lopment and the future of gene therapies. Challenges related to translational efficacy, mRNA stability, immunogenicity, and ensuring the quality of final products have been significantly improved by recent advancements in mRNA engineering...
Source: European Journal of Drug Metabolism and Pharmacokinetics - September 1, 2023 Category: Drugs & Pharmacology Source Type: research
Comparable efficacy and safety of COVID-19 vaccines for patients receiving tegafur –uracil as postoperative adjuvant chemotherapy
ConclusionsThe efficacy and safety of the SARS-CoV-2 vaccines for NSCLC patients who received postoperative adjuvant UFT chemotherapy were comparable to those for NSCLC patients who did not receive postoperative adjuvant UFT chemotherapy.Clinical trial registrationThis study was registered with the University Hospital Medical Information Network (UMIN) in Japan (UMIN000047380).
Source: Surgery Today - September 1, 2023 Category: Surgery Source Type: research
Comprehensive care of adults with respiratory diseases must include vaccines
Vaccines are among the most effective tools we have to improve and save lives, but only if they are administered to eligible patients. In this issue, Naeger et al1 highlight the major opportunities that the health care community has to achieve high adult vaccination rates. These vaccines include those for prevention of coronavirus disease 2019 (COVID-19), pneumococcal, and influenza, diseases that respiratory health professionals are most aware of, plus pertussis (in Tdap), herpes zoster (HZ, shingles), and as of May 3, 2023, respiratory syncytial viral, for which adults with asthma and chronic obstructive pulmonary diseas...
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Barbara P. Yawn, Dennis Williams, Gregory Poland Tags: Editorial Source Type: research
Novel B-Cell Epitopes of Non-Neutralizing Antibodies in the Receptor-Binding Domain of the SARS-CoV-2 S-Protein with Different Effects on the Severity of COVID-19
In conclusion, despite the clear significance of anti -RBD antibodies in the effective immune response against SARS-CoV-2, it is important to analyze their virus-neutralizing activity and to confirm absence of the antibody-mediated enhancement of infection by the anti-RBD antibodies.
Source: Biochemistry (Moscow) - September 1, 2023 Category: Biochemistry Source Type: research
mRNA-Based Nanomedicine: A New Strategy for Treating Infectious Diseases and Beyond
AbstractMessenger RNA (mRNA) has emerged as a new therapeutic agent for the prevention and treatment of a wide range of diseases. The recent achievement of the two lipid nanoparticle-mRNA vaccines developed by Moderna and Pfizer-BioNTech against coronavirus 2019 (COVID-19) disease in record time highlights the huge potential of mRNA technology and reshaping the landscape of vaccine deve lopment and the future of gene therapies. Challenges related to translational efficacy, mRNA stability, immunogenicity, and ensuring the quality of final products have been significantly improved by recent advancements in mRNA engineering...
Source: European Journal of Drug Metabolism and Pharmacokinetics - September 1, 2023 Category: Drugs & Pharmacology Source Type: research
Practices will struggle with tight timeframe for COVID-19 jab payments, warns BMA
Five-week windows in which practices can claim supplementary pay for COVID-19 vaccinations this autumn should be extended to boost participation in the jab campaign, GP leaders have warned.
Source: GP Online News - August 31, 2023 Category: Primary Care Tags: Coronavirus Source Type: news
The Important Role of Interleukin-2 in COVID-19
J Immunol Res. 2023 Aug 22;2023:7097329. doi: 10.1155/2023/7097329. eCollection 2023.ABSTRACTThere is controversial literature about the effects of the interleukin-2 (IL-2) cytokine family in COVID-19 pathogenesis and immunity. So we aimed to identify the potential in the role of the IL-2 family in COVID-19. A narrative review search was done through online databases, including PubMed, Scopus, and Web of Science. The search deadline was up to December 2022. We applied no time limits for the searching strategy. After retrieving articles from the databases, the authors summarized the data into two data extraction tables. The...
Source: Journal of Immunology Research - August 31, 2023 Category: Allergy & Immunology Authors: Leila Ghanbari Naeini Laleh Abbasi Farzaneh Karimi Pajman Kokabian Fahimeh Abdi Abyaneh Delaram Naderi Source Type: research
An Insight into Multisystem Inflammatory Syndrome in Adults Associated with Recent SARS-COV-2 Infection: A Case Series
CONCLUSIONS: Multisystem inflammatory syndrome (MIS) can affect children (MIS-C) as well as adults (MIS-A). MIS-A is a serious, life-threatening, hyperinflammatory febrile syndrome associated with recent COVID-19 infection and involves multiple organs like the heart, lungs, kidneys, brain, gastrointestinal organs, skin, eyes etc. Clinical suspicion and testing for evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are needed to identify and treat adults suspected to have MIS-A. This case series demonstrates that even the elderly population can be affected and that administration of IVIg and ...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Arun Agarwal Rekha Jakhar Ambika Sharma Aditi Sharma Aakanksha Agarwal Anju Kumari Source Type: research
The Important Role of Interleukin-2 in COVID-19
J Immunol Res. 2023 Aug 22;2023:7097329. doi: 10.1155/2023/7097329. eCollection 2023.ABSTRACTThere is controversial literature about the effects of the interleukin-2 (IL-2) cytokine family in COVID-19 pathogenesis and immunity. So we aimed to identify the potential in the role of the IL-2 family in COVID-19. A narrative review search was done through online databases, including PubMed, Scopus, and Web of Science. The search deadline was up to December 2022. We applied no time limits for the searching strategy. After retrieving articles from the databases, the authors summarized the data into two data extraction tables. The...
Source: Journal of Immunology Research - August 31, 2023 Category: Allergy & Immunology Authors: Leila Ghanbari Naeini Laleh Abbasi Farzaneh Karimi Pajman Kokabian Fahimeh Abdi Abyaneh Delaram Naderi Source Type: research
An Insight into Multisystem Inflammatory Syndrome in Adults Associated with Recent SARS-COV-2 Infection: A Case Series
CONCLUSIONS: Multisystem inflammatory syndrome (MIS) can affect children (MIS-C) as well as adults (MIS-A). MIS-A is a serious, life-threatening, hyperinflammatory febrile syndrome associated with recent COVID-19 infection and involves multiple organs like the heart, lungs, kidneys, brain, gastrointestinal organs, skin, eyes etc. Clinical suspicion and testing for evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are needed to identify and treat adults suspected to have MIS-A. This case series demonstrates that even the elderly population can be affected and that administration of IVIg and ...
Source: Journal of the Association of Physicians of India - August 31, 2023 Category: General Medicine Authors: Arun Agarwal Rekha Jakhar Ambika Sharma Aditi Sharma Aakanksha Agarwal Anju Kumari Source Type: research
The Important Role of Interleukin-2 in COVID-19
J Immunol Res. 2023 Aug 22;2023:7097329. doi: 10.1155/2023/7097329. eCollection 2023.ABSTRACTThere is controversial literature about the effects of the interleukin-2 (IL-2) cytokine family in COVID-19 pathogenesis and immunity. So we aimed to identify the potential in the role of the IL-2 family in COVID-19. A narrative review search was done through online databases, including PubMed, Scopus, and Web of Science. The search deadline was up to December 2022. We applied no time limits for the searching strategy. After retrieving articles from the databases, the authors summarized the data into two data extraction tables. The...
Source: Journal of Immunology Research - August 31, 2023 Category: Allergy & Immunology Authors: Leila Ghanbari Naeini Laleh Abbasi Farzaneh Karimi Pajman Kokabian Fahimeh Abdi Abyaneh Delaram Naderi Source Type: research
