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Total 1080 results found since Jan 2013.
‘Lessons have been forgotten’: is the UK ready for a new Covid variant?
With worrying mutations, limited vaccine rollout, vastly reduced testing and a creaking health service, experts are predicting a tough few months ahead“New variant”, “care home outbreak”, “cases rising”: you’d be forgiven if the headlines aroundPirola, or BA.2.86, the latest Covid strain to arrive in the UK, had triggered a severe case of pandemic deja vu. More than two years since the UK ’s last lockdown, concerns over BA.2.86 – known to have infected dozens of people in the UK as of last weekend, including 28 at a Norfolk care home – have been rising. The worry is over what is “the most striking Sar...
Source: Guardian Unlimited Science - September 16, 2023 Category: Science Authors: Charlotte Lytton Tags: Coronavirus NHS Vaccines and immunisation Science Health Infectious diseases Society Source Type: news
Pediatric cancer care management during the COVID-19 pandemic: a review of the literature and a single-centre real-life experience of an Italian pediatric oncology unit
In conclusion, we reported the real-life experience of our pediatric oncology unit during the pandemic period.EXPERT OPINION: Starting from the data available in literature, and our experience, showing the rarity of severe COVID-19 disease in pediatric patients with solid tumors, we recommend carefully tailoring all the oncological treatments (chemotherapy/targeted therapy/stem cell transplantation/radiotherapy). The aim is the preservation of the treatment's timing, balanced with an evaluation of possible severe COVID-19 disease.PMID:37712347 | DOI:10.1080/14737140.2023.2245148
Source: Expert Review of Anticancer Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Olga Nigro Chiara Oltolini Federica Barzaghi Caterina Uberti Foppa Maria Pia Cicalese Maura Massimino Elisabetta Schiavello Source Type: research
RNA nanotechnology: A new chapter in targeted therapy
Colloids Surf B Biointerfaces. 2023 Sep 6;230:113533. doi: 10.1016/j.colsurfb.2023.113533. Online ahead of print.ABSTRACTNanoparticles have been widely studied in the fields of biotechnology, pharmacy, optics and medicine and have broad application prospects. Numerous studies have shown significant interest in utilizing nanoparticles for chemically coating or coupling drugs, aiming to address the challenges of drug delivery, including degradability and uncertainty. Furthermore, the utilization of lipid nanoparticles loaded with novel coronavirus antigen mRNA to control the COVID-19 pandemic has led to a notable surge in re...
Source: Colloids and Surfaces - September 15, 2023 Category: Biotechnology Authors: Tongtong Lv Yingying Meng Yifan Liu Yukun Han Hongwu Xin Xiaochun Peng Jinbai Huang Source Type: research
Pediatric cancer care management during the COVID-19 pandemic: a review of the literature and a single-centre real-life experience of an Italian pediatric oncology unit
In conclusion, we reported the real-life experience of our pediatric oncology unit during the pandemic period.EXPERT OPINION: Starting from the data available in literature, and our experience, showing the rarity of severe COVID-19 disease in pediatric patients with solid tumors, we recommend carefully tailoring all the oncological treatments (chemotherapy/targeted therapy/stem cell transplantation/radiotherapy). The aim is the preservation of the treatment's timing, balanced with an evaluation of possible severe COVID-19 disease.PMID:37712347 | DOI:10.1080/14737140.2023.2245148
Source: Expert Review of Anticancer Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Olga Nigro Chiara Oltolini Federica Barzaghi Caterina Uberti Foppa Maria Pia Cicalese Maura Massimino Elisabetta Schiavello Source Type: research
RNA nanotechnology: A new chapter in targeted therapy
Colloids Surf B Biointerfaces. 2023 Sep 6;230:113533. doi: 10.1016/j.colsurfb.2023.113533. Online ahead of print.ABSTRACTNanoparticles have been widely studied in the fields of biotechnology, pharmacy, optics and medicine and have broad application prospects. Numerous studies have shown significant interest in utilizing nanoparticles for chemically coating or coupling drugs, aiming to address the challenges of drug delivery, including degradability and uncertainty. Furthermore, the utilization of lipid nanoparticles loaded with novel coronavirus antigen mRNA to control the COVID-19 pandemic has led to a notable surge in re...
Source: Colloids and Surfaces - September 15, 2023 Category: Biotechnology Authors: Tongtong Lv Yingying Meng Yifan Liu Yukun Han Hongwu Xin Xiaochun Peng Jinbai Huang Source Type: research
Pediatric cancer care management during the COVID-19 pandemic: a review of the literature and a single-centre real-life experience of an Italian pediatric oncology unit
In conclusion, we reported the real-life experience of our pediatric oncology unit during the pandemic period.EXPERT OPINION: Starting from the data available in literature, and our experience, showing the rarity of severe COVID-19 disease in pediatric patients with solid tumors, we recommend carefully tailoring all the oncological treatments (chemotherapy/targeted therapy/stem cell transplantation/radiotherapy). The aim is the preservation of the treatment's timing, balanced with an evaluation of possible severe COVID-19 disease.PMID:37712347 | DOI:10.1080/14737140.2023.2245148
Source: Expert Review of Anticancer Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Olga Nigro Chiara Oltolini Federica Barzaghi Caterina Uberti Foppa Maria Pia Cicalese Maura Massimino Elisabetta Schiavello Source Type: research
Stimuli-Responsive Hydrogel Microcapsules Harnessing the COVID-19 Immune Response for Cancer Therapeutics
We present the development of stimuli-responsive microcapsules, loaded with a viral immunogenetic agent, harnessing the immune response against the Coronavirus Disease 2019, COVID-19, to selectively attack liver cancer cells (hepatoma) or recognize breast cancer or hepatoma, by expression of green fluorescence protein, GFP. The pH-responsive microcapsules, modified with DNA-tetrahedra nanostructures, increased hepatoma permeation by 50%. Incorporation of a GFP-encoding lentivirus vector inside the tumor-targeting pH-stimulated miRNA-triggered and Alpha-fetoprotein-dictated microcapsules enables the demonstration of neoplas...
Source: Angewandte Chemie - September 7, 2023 Category: Chemistry Authors: Amit Fischer Avner Ehrlich Yevgeni Plotkin Yu Ouyang Klil Asulin Ioannidis Konstantinos Chunhai Fan Yaakov Nahmias Itamar Willner Source Type: research
COVID-19 vaccination is associated with enhanced efficacy of anti-PD-(L)1 immunotherapy in advanced NSCLC patients: a real-world study
Coronavirus disease 2019 (COVID-19) vaccine has played a major role in ending the pandemic. However, little is known about the influence of COVID-19 vaccine on the efficacy of immunotherapy in patients with no...
Source: Infectious Agents and Cancer - September 7, 2023 Category: Cancer & Oncology Authors: Yunfei Qian, Zhuxian Zhu, Yin-Yuan Mo and Ziqiang Zhang Tags: Research Source Type: research
Racial and Ethnic Variation in COVID-19 Vaccination Uptake Among Medicare Beneficiaries with Cancer History
ConclusionsResults indicate racial and ethnic differences in vaccine uptake among Medicare beneficiaries with cancer history. Effective strategies are needed to help increase vaccine confidence and uptake among adults with cancer history.
Source: Journal of Racial and Ethnic Health Disparities - September 6, 2023 Category: International Medicine & Public Health Source Type: research
Patient Report on the Impact of Coronavirus Disease 2019 and Living With Lung Cancer
CONCLUSIONS: An integrative patient-reported view on the impact of COVID-19 is important for adequate preparation to ensure undisrupted treatment and allocation of resources.PMID:37663676 | PMC:PMC10472288 | DOI:10.1016/j.jtocrr.2023.100549
Source: Clinical Lung Cancer - September 4, 2023 Category: Cancer & Oncology Authors: Tendai M Chihuri Upal Basu Roy Amy Moore Anne-Marie Baird Tracey L Grant Bellinda L King-Kallimanis Source Type: research
