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Procedure: Lung Transplant

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Total 1013 results found since Jan 2013.

The Next Generation COVID ‐19 Antiviral; Niclosamide‐Based Inorganic Nanohybrid System Kills SARS‐CoV‐2
The solubility challenge of niclosamide is resolved with an exclusive drug delivery technology using biocompatible inorganic MgO and hydroxypropyl methylcellulose polymer that has enhanced the solubility and intestinal absorption, thereby prolonged and sustained release of niclosamide, eventually improving the antiviral effect in the lungs without causing any adverse effects according to the preclinical and clinical studies. AbstractThe coronavirus disease 2019 (COVID-19) pandemic is a serious global threat with surging new variants of concern. Although global vaccinations have slowed the pandemic, their longevity is still...
Source: Small - August 28, 2023 Category: Nanotechnology Authors: Goeun Choi, N. Sanoj Rejinold, Huiyan Piao, Young Bae Ryu, Hyung ‐Jun Kwon, In Chul Lee, Jeong In Seo, Hye Hyun Yoo, Geun‐woo Jin, Jin‐Ho Choy Tags: Research Article Source Type: research

Early outcomes of lung transplantation with lung allografts from coronavirus disease 2019 (COVID-19) –positive donors
This study aimed to clarify the early outcomes of lung transplantation with COVID-19–positive donors.
Source: The Journal of Thoracic and Cardiovascular Surgery - August 23, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Jae Hyun Jeon, Takashi Harano, John C.S. Rodman, Megha Sheth, Sean C. Wightman, Scott M. Atay, Anthony W. Kim Tags: Transplantation Source Type: research

Early outcomes of lung transplantation with lung allografts from COVID-19-positive donors
This study aimed to clarify the early outcomes of lung transplantation with COVID-19-positive donors.
Source: The Journal of Thoracic and Cardiovascular Surgery - August 23, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Jae Hyun Jeon, Takashi Harano, John C.S. Rodman, Megha Sheth, Sean C. Wightman, Scott M. Atay, Anthony W. Kim Source Type: research

Deep Learning for Medical Imaging: Use Cases and Network Types
Conclusion Medical image analysis solutions powered by deep learning technologies can reduce the risk of diagnostic errors and ensure timely interventions. But how to implement such a tool successfully? The key to successful deployment is cooperation with an experienced machine-learning solutions provider. Professional technical experts will help you choose an optimal architecture for your clinic’s specific goals and ensure effective model training. About Mariia Kovalova Mariia Kovalova is a Healthcare Technology Researcher at Itransition, a custom software development company headquartered in Denver, CO. Having work...
Source: EMR and HIPAA - August 18, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT CNN Convolutional Neural Networks Deep Learning GAN Generative Adversarial Networks Healthcare AI Healthcare Neural Networks Itransition MADGAN Mariia Kovalova Medical Imaging Source Type: blogs

Is Transplantation with Coronavirus Disease-2019 Positive Donor Lungs Safe? A U.S. Nationwide Analysis
CONCLUSIONS: Thirty-day and 3-month survival outcomes were similar between recipients receiving lungs from donors with recent positive COVID-19 testing compared to donors with negative COVID-19 testing, suggesting highly selected COVID-19 positive donors without evidence of active infection may be safely considered for transplant. Further studies should explore long term outcomes to provide reassurance about the safety of this practice.PMID:37506993 | DOI:10.1016/j.athoracsur.2023.05.048
Source: The Annals of Thoracic Surgery - July 28, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Richa Asija Ruby Singh Dane C Paneitz Stanley Wolfe Chijioke Chukwudi Eriberto Michel Seyed Alireza Rabi Nathaniel Langer Asishana Osho Asvin Ganapathi Source Type: research

Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients
Cell Mol Life Sci. 2023 Jul 28;80(8):234. doi: 10.1007/s00018-023-04870-0.ABSTRACTThe human chemokine stromal cell-derived factor-1 (SDF-1) or CXCL12 is involved in several homeostatic processes and pathologies through interaction with its cognate G protein-coupled receptor CXCR4. Recent research has shown that CXCL12 is present in the lungs and circulation of patients with coronavirus disease 2019 (COVID-19). However, the question whether the detected CXCL12 is bioactive was not addressed. Indeed, the activity of CXCL12 is regulated by NH2- and COOH-terminal post-translational proteolysis, which significantly impairs its ...
Source: Cellular and Molecular Life Sciences : CMLS - July 28, 2023 Category: Cytology Authors: Seppe Cambier Fabio Beretta No ëmie Pörtner Mieke Metzemaekers Ana Carolina de Carvalho Erik Martens Janne Kaes Celine Aelbrecht Cato Jacobs Pierre Van Mol Els Wauters Philippe Meersseman Greet Hermans Rafael Elias Marques Bart Vanaudenaerde Robin Vos J Source Type: research

Is Transplantation with Coronavirus Disease-2019 Positive Donor Lungs Safe? A U.S. Nationwide Analysis
CONCLUSIONS: Thirty-day and 3-month survival outcomes were similar between recipients receiving lungs from donors with recent positive COVID-19 testing compared to donors with negative COVID-19 testing, suggesting highly selected COVID-19 positive donors without evidence of active infection may be safely considered for transplant. Further studies should explore long term outcomes to provide reassurance about the safety of this practice.PMID:37506993 | DOI:10.1016/j.athoracsur.2023.05.048
Source: The Annals of Thoracic Surgery - July 28, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Richa Asija Ruby Singh Dane C Paneitz Stanley Wolfe Chijioke Chukwudi Eriberto Michel Seyed Alireza Rabi Nathaniel Langer Asishana Osho Asvin Ganapathi Source Type: research

Cellular and humoral immune responses after a third dose of SARS-CoV-2 mRNA vaccine in lung transplant recipients in Japan
CONCLUSION: Although the third dose of mRNA vaccine in LTx recipients was effective and safe, impaired cellular and humoral responses to SARS-CoV-2 spike protein were noted. Given lower antibody production and establishing vaccine safety, repeating the administration of mRNA vaccine will lead to robust protection in such a high-risk population (jRCT1021210009).PMID:37328349 | PMC:PMC10250153 | DOI:10.1016/j.vaccine.2023.06.011
Source: Vaccine - June 16, 2023 Category: Allergy & Immunology Authors: Masahiro Ui Takashi Hirama Miki Akiba Masako Honda Toshiaki Kikuchi Yoshinori Okada Source Type: research

German Heart Surgery Report 2022: The Annual Updated Registry of the German Society for Thoracic and Cardiovascular Surgery
Thorac Cardiovasc Surg. 2023 Jun 16. doi: 10.1055/s-0043-1769597. Online ahead of print.ABSTRACTBased on a longtime voluntary registry, founded by the German Society for Thoracic and Cardiovascular Surgery (GSTCVS/DGTHG) in 1980, well-defined data of all cardiac, thoracic, and vascular surgery procedures performed in 78 German heart surgery departments during the year 2022 are analyzed. Under the decreasing interference of the worldwide coronavirus disease 2019 pandemic, a total of 162,167 procedures were submitted to the registry. A total of 93,913 of these operations are summarized as heart surgery procedures in a classi...
Source: The Thoracic and Cardiovascular Surgeon - June 16, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Andreas Beckmann Renate Meyer Jana Lewandowski Andreas Markewitz Daniela Bla ßfeld Andreas B öning Source Type: research

Cellular and humoral immune responses after a third dose of SARS-CoV-2 mRNA vaccine in lung transplant recipients in Japan
CONCLUSION: Although the third dose of mRNA vaccine in LTx recipients was effective and safe, impaired cellular and humoral responses to SARS-CoV-2 spike protein were noted. Given lower antibody production and establishing vaccine safety, repeating the administration of mRNA vaccine will lead to robust protection in such a high-risk population (jRCT1021210009).PMID:37328349 | PMC:PMC10250153 | DOI:10.1016/j.vaccine.2023.06.011
Source: Vaccine - June 16, 2023 Category: Allergy & Immunology Authors: Masahiro Ui Takashi Hirama Miki Akiba Masako Honda Toshiaki Kikuchi Yoshinori Okada Source Type: research