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Retrospective Case-Control Study of REGEN-COV (casirivimab and imdevimab) Therapy for Patients with COVID-19 and Cancer Using the United States MarketScan ® Database
Conclusion Patients with cancer treated with REGEN-COV experienced a decreased risk for hospitalization, hospitalization duration, and total COVID-19-related costs. Patients with cancer were at a higher risk of being hospitalized for COVID-19 than were those without cancer. The use of neutralizing antibody therapy may reduce the risk of severe COVID-19 infection for patients with cancer with an otherwise high risk. Future replication studies should be conducted using other databases that include Medicaid users and other insured persons for comparison and validation.PMID:37666220 | DOI:10.1159/000533614
Source: Oncology - September 4, 2023 Category: Cancer & Oncology Authors: Kazue Takemoto Source Type: research

Update on Access to Coronavirus-related Articles in PubMed Central (PMC) COVID-19 Collection after end of Public Health Emergency
Early in the COVID-19 pandemic, the National Library of Medicine (NLM)collaborated with publishers and scholarly societies to expand access to coronavirus-related journal articles in PubMed Central (PMC). Through this collaboration, more than 50 publishers made more than 350,000 coronavirus-related articles accessible under various license terms through thePMC COVID-19 Collection (previously the PMC COVID-19 Public Health Emergency Initiative).As COVID-19 emergency declarations expired in the United States and around the globe, so too did article-level license terms for use of some of these articles. Most of the articles d...
Source: PubMed Central News - August 30, 2023 Category: Databases & Libraries Source Type: news

Injury patterns and outcomes at a single pediatric trauma center during the coronavirus disease 19 pandemic - Sullivan TM, Scheese D, Jain E, Milestone ZP, Haynes J, Boomer LA.
INTRODUCTION: The coronavirus disease 19 (COVID-19) pandemic is reported to have changed injury patterns, prevalence, and outcomes across multiple institutions in the United States. Interpretation of aggregate data is difficult because injury patterns vary...
Source: SafetyLit - August 28, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Dilemmas and options for COVID-19 vaccination in children
AbstractOver 16 million children have been detected positive for the coronavirus disease 2019 (COVID-19) in the United States since the outbreak of the pandemic. In general, children infected with severe acute respiratory syndrome coronavirus type 2 tend to have lighter symptoms than adults. However, in some case s, the infection can develop into severe forms, such as multisystem inflammatory syndrome in children. Moreover, long-term public health preventive interventions have had some negative effects on the physical and mental health of children. Given the important role that vaccination plays in reducing severe illnes...
Source: Italian Journal of Pediatrics - August 25, 2023 Category: Pediatrics Source Type: research

UPDATE 2-Novavax ' s updated COVID shot shows immune response against subvariant Eris
Novavax Inc said on Tuesday its updated protein-based COVID-19 vaccine generated an immune response against emerging forms of coronavirus such as the "Eris" subvariant in small studies in animals. COVID infections and hospitalizations have been rising in the United States, Europe and Asia, with…#novavaxinc #omicron #pfizer #novavax #xbb #eg51 #xbb1166 #khushimandowara #bengaluru #shilpimajumdar
Source: Reuters: Health - August 22, 2023 Category: Consumer Health News Source Type: news

Population-level trends in asthma and chronic obstructive pulmonary disease emergency department visits and hospitalizations before and during the coronavirus disease 2019 pandemic in the United States
Previous studies have identified reductions in exacerbations of chronic lung disease in many locales after onset of the coronavirus disease 2019 (COVID-19) pandemic.
Source: Annals of Allergy, Asthma and Immunology - August 22, 2023 Category: Allergy & Immunology Authors: Adam Gaffney, David U. Himmelstein, Steffie Woolhandler Source Type: research

Hospitalization Among Patients Treated With Molnupiravir: A Retrospective Study of Administrative Data
This study aimed to describe patient characteristics and health outcomes in a cohort of adult patients treated with molnupiravir in an outpatient setting in the United States.METHODS: This was a retrospective cohort study of adults identified in the HealthVerity database with a pharmacy claim for molnupiravir between December 24, 2021, and April 14, 2022. Hospitalization and health care use were assessed over the 28 days after the molnupiravir pharmacy claim.FINDINGS: Among 26,554 patients identified, 71.1% were aged ≥50 years and 58.9% were female. A total of 8794 patients (33.1%) had received at least 1 dose of the COV...
Source: Clinical Therapeutics - August 19, 2023 Category: Drugs & Pharmacology Authors: Girish Prajapati Amar Das Yezhou Sun Eileen Fonseca Source Type: research

Influenza Vaccination Among Pregnant People Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Obstet Gynecol. 2023 Sep 1;142(3):636-639. doi: 10.1097/AOG.0000000000005285. Epub 2023 Aug 3.ABSTRACTThere are limited data on influenza vaccination coverage among pregnant people in the United States during the coronavirus disease 2019 (COVID-19) pandemic. Within the Vaccine Safety Datalink, we conducted a retrospective cohort study to examine influenza vaccination coverage during the 2016-2017 through the 2021-2022 influenza seasons among pregnant people aged 18-49 years. Using influenza vaccines administered through March each season, we assessed crude coverage by demographic and clinical characteristics. Annual influe...
Source: Obstetrics and Gynecology - August 17, 2023 Category: OBGYN Authors: Stephanie A Irving Bradley Crane Eric Weintraub Tia L Kauffman Neon Brooks Suchita A Patel Hilda Razzaghi Edward A Belongia Matthew F Daley Darios Getahun Sungching C Glenn Simon J Hambidge Lisa A Jackson Elyse Kharbanda Nicola P Klein Ousseny Zerbo Allis Source Type: research

Substance Use Disorders: Basic Overview for the Anesthesiologist
Anesth Analg. 2023 Sep 1;137(3):508-520. doi: 10.1213/ANE.0000000000006281. Epub 2023 Aug 17.ABSTRACTSubstance use disorders (SUDs) represent a current major public health concern in the United States and around the world. Social and economic stressors secondary to the coronavirus disease 2019 (COVID-19) pandemic have likely led to an increase in SUDs around the world. This chronic, debilitating disease is a prevalent health problem, and yet many clinicians do not have adequate training or clinical experience diagnosing and treating SUDs. Anesthesiologists and other perioperative medical staff frequently encounter patients...
Source: Anesthesia and Analgesia - August 17, 2023 Category: Anesthesiology Authors: Federico Jimenez Ruiz Nafisseh S Warner Gregory Acampora John R Coleman Lynn Kohan Source Type: research

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