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Comparison of Clinical Characteristics and Peripheral Blood Tests of COVID-19 and Influenza B Patients
This study aimed to investigate the differences in clinical features and routine peripheral blood testing between coronavirus disease 2019 (COVID-19) infection and influenza B infection. Patients with COVID-19 and influenza B admitted to our fever clinic from January 1, 2022 to June 30, 2022 were recruited. A total of 607 patients were included (301 with COVID-19 infection and 306 with influenza B infection). The results of a statistical analysis showed that 1) patients with COVID-19 infection were older and had a lower temperature and shorter duration from fever onset to clinic visit than patients with influenza B infecti...
Source: Am J Trop Med Hyg - March 13, 2023 Category: Infectious Diseases Authors: Shan Yu Source Type: research

IJERPH, Vol. 20, Pages 4918: A Case of Autoimmune Small Fiber Neuropathy as Possible Post COVID Sequelae
In conclusion, though biopsy results could not distinguish a cause of the disease, SARS-CoV-2 infection can be discussed as a likely trigger for the patient’s autoimmune reactions.
Source: International Journal of Environmental Research and Public Health - March 10, 2023 Category: Environmental Health Authors: Noel G. Panagiotides Fritz Zimprich Klaus Machold Oliver Schlager Markus M üller Sebastian Ertl Henriette L öffler-Stastka Renate Koppensteiner Patricia P. Wadowski Tags: Case Report Source Type: research

Viruses, Vol. 15, Pages 701: Elevated SARS-CoV-2-Specific Antibody Levels in Patients with Post-COVID Syndrome
S. Heitmann With the routine use of effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, the number of life-threatening coronavirus disease 2019 (COVID-19) courses have largely been reduced. However, multiple COVID-19 convalescents, even after asymptomatic to moderate disease, suffer from post-COVID syndrome, with relevant limitations in daily life. The pathophysiologic mechanisms of post-COVID syndrome are still elusive, with dysregulation of the immune system suggested as a central mechanism. Here, we assessed COVID-19 post-infectious symptoms (5–6 months after PCR-confirmed ...
Source: Viruses - March 8, 2023 Category: Virology Authors: Christopher Hackenbruch Yacine Maringer Christian M. Tegeler Juliane S. Walz Annika Nelde Jonas S. Heitmann Tags: Article Source Type: research

Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata over 52 Weeks of Continuous Therapy in Two Phase III Trials (BRAVE-AA1 and BRAVE-AA2)
ConclusionEfficacy of baricitinib for adults with severe AA continuously improved over 52 weeks, indicating that long-term treatment may be necessary to observe maximum clinical benefit. There were no new safety signals.ClinicalTrials RegistrationClinicalTrials.gov NCT03570749 and NCT03899259.Video abstractEfficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata: Week-52 Results from BRAVE-AA1 and BRAVE-AA2
Source: American Journal of Clinical Dermatology - March 1, 2023 Category: Dermatology Source Type: research

Blood-brain barrier function in response to SARS-CoV-2 and its spike protein
Neurol Neurochir Pol. 2023 Feb 22. doi: 10.5603/PJNNS.a2023.0014. Online ahead of print.ABSTRACTThe typical manifestation of coronavirus 2 (CoV-2) infection is a severe acute respiratory syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can also affect t he b rain, c ausing c hronic n eurological s ymptoms, variously known as long, post, post-acute, or persistent COVID-19 condition, and affecting up to 40% of patients. The symptoms (fatigue, dizziness, headache, sleep disorders, malaise, disturbances of memory and mood) usually are mild and resolve spontaneously. However, some patients develop acute ...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Łukasz Suprewicz Krzysztof Fiedoruk Agata Czarnowska Marcin Sadowski Agnieszka Strzelecka Peter A Galie Paul A Janmey Alina Ku łakowska Robert Bucki Source Type: research