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Vaccination: Pneomococcal Vaccine
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Total 3003 results found since Jan 2013.
Identifying gaps in vaccination perception after mandating the COVID-19 vaccine in Saudi Arabia
CONCLUSION: The study showed that participants were willing to receive the vaccination if they were aware of the general benefits of vaccinations. Therefore, health education and campaigns toward recommended vaccines for high-risk group are essential and needed.PMID:37164821 | DOI:10.1016/j.vaccine.2023.04.057
Source: Vaccine - May 10, 2023 Category: Allergy & Immunology Authors: Nada Alsuhebany Shuroug A Alowais Atheer Aldairem Sumaya N Almohareb Khalid Bin Saleh Khawla M Kahtani Lama I Alnashwan Saeed M Alay Mohammed G Alamri Ghaida K Alhathlol Ibrahim Asiri Source Type: research
BCG ∆BCG1419c and BCG differ in induction of autophagy, c-di-GMP content, proteome, and progression of lung pathology in Mycobacterium tuberculosis HN878-infected male BALB/c mice
Vaccine. 2023 May 8:S0264-410X(23)00489-9. doi: 10.1016/j.vaccine.2023.04.065. Online ahead of print.ABSTRACTThe efficacy of BCG vaccines against Mycobacterium tuberculosis (Mtb) strains of lineage 2 (Beijing) in preclinical models and humans has been questioned. We have developed BCG∆BCG1419c, by deletion of BCG1419c in BCG Pasteur, which improved control of tuberculosis (TB) in preclinical models. Here, we compared the capacity of BCG and BCG∆BCG1419c to induce autophagy in murine macrophages, modify c-di-GMP content and transcript levels of BCG1416c, encoding the enzyme responsible for c-di-GMP synthesis/degradation...
Source: Vaccine - May 10, 2023 Category: Allergy & Immunology Authors: Michel de Jes ús Aceves-Sánchez Jorge Alberto Barrios-Pay án Cristian Alfredo Segura-Cerda Mario Alberto Flores-Valdez Dulce Mata-Espinosa C ésar Pedroza-Roldán Rahul Yadav Deepak Kumar Saini Miguel Angel de la Cruz Miguel A Ares Helle Bielefeldt-Ohm Source Type: research
Identifying gaps in vaccination perception after mandating the COVID-19 vaccine in Saudi Arabia
CONCLUSION: The study showed that participants were willing to receive the vaccination if they were aware of the general benefits of vaccinations. Therefore, health education and campaigns toward recommended vaccines for high-risk group are essential and needed.PMID:37164821 | PMC:PMC10130326 | DOI:10.1016/j.vaccine.2023.04.057
Source: Vaccine - May 10, 2023 Category: Allergy & Immunology Authors: Nada Alsuhebany Shuroug A Alowais Atheer Aldairem Sumaya N Almohareb Khalid Bin Saleh Khawla M Kahtani Lama I Alnashwan Saeed M Alay Mohammed G Alamri Ghaida K Alhathlol Ibrahim Asiri Source Type: research
BCG ∆BCG1419c and BCG differ in induction of autophagy, c-di-GMP content, proteome, and progression of lung pathology in Mycobacterium tuberculosis HN878-infected male BALB/c mice
Vaccine. 2023 May 8:S0264-410X(23)00489-9. doi: 10.1016/j.vaccine.2023.04.065. Online ahead of print.ABSTRACTThe efficacy of BCG vaccines against Mycobacterium tuberculosis (Mtb) strains of lineage 2 (Beijing) in preclinical models and humans has been questioned. We have developed BCG∆BCG1419c, by deletion of BCG1419c in BCG Pasteur, which improved control of tuberculosis (TB) in preclinical models. Here, we compared the capacity of BCG and BCG∆BCG1419c to induce autophagy in murine macrophages, modify c-di-GMP content and transcript levels of BCG1416c, encoding the enzyme responsible for c-di-GMP synthesis/degradation...
Source: Vaccine - May 10, 2023 Category: Allergy & Immunology Authors: Michel de Jes ús Aceves-Sánchez Jorge Alberto Barrios-Pay án Cristian Alfredo Segura-Cerda Mario Alberto Flores-Valdez Dulce Mata-Espinosa C ésar Pedroza-Roldán Rahul Yadav Deepak Kumar Saini Miguel Angel de la Cruz Miguel A Ares Helle Bielefeldt-Ohm Source Type: research
Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung
EMBO Mol Med. 2023 May 9:e17084. doi: 10.15252/emmm.202217084. Online ahead of print.ABSTRACTBacillus Calmette-Guérin (BCG) still remains the only licensed vaccine for TB and has been shown to provide nonspecific protection against unrelated pathogens. This has been attributed to the ability of BCG to modulate the innate immune system, known as trained innate immunity (TII). Trained innate immunity is associated with innate immune cells being in a hyperresponsive state leading to enhanced host defense against heterologous infections. Both epidemiological evidence and prospective studies demonstrate cutaneous BCG vaccine-i...
Source: Molecular Medicine - May 9, 2023 Category: Molecular Biology Authors: Alisha Kang Gluke Ye Ramandeep Singh Sam Afkhami Jegarubee Bavananthasivam Xiangqian Luo Maryam Vaseghi-Shanjani Fatemah Aleithan Anna Zganiacz Mangalakumari Jeyanathan Zhou Xing Source Type: research
Outer Membrane Vesicle-Coated Nanoparticle Vaccine Protects Against < em > Acinetobacter baumannii < /em > Pneumonia and Sepsis
We report a vaccine platform combining precise and replicable nanoparticle technology with immunogenic A. baumannii OMVs (Ab-OMVs). Gold nanoparticle cores coated with Ab-OMVs (Ab-NPs) induced robust IgG titers in rabbits that enhanced human neutrophil opsonophagocytic killing and passively protected against lethal A. baumannii sepsis in mice. Active Ab-NP immunization in mice protected against sepsis and pneumonia, accompanied by B cell recruitment to draining lymph nodes, activation of dendritic cell markers, improved splenic neutrophil responses, and mitigation of proinflammatory cytokine storm. Nanoparticles are an eff...
Source: Cell Research - May 8, 2023 Category: Cytology Authors: Elisabet Bjanes Jiarong Zhou Tariq Qayum Nishta Krishnan Raymond H Zurich Nitasha D Menon Alexandria Hoffman Ronnie H Fang Liangfang Zhang Victor Nizet Source Type: research
Multi-pathogen based chimeric vaccine to fight against COVID-19 and concomitant coinfections
CONCLUSION: The in silico immune simulation analysis has shown a high level of cytokines and IgG after a three-dose injection. Hence, this strategy could be a better way to decrease the disease's severity and could be used as a weapon to prevent this pandemic.PMID:37148345 | DOI:10.1007/s10529-023-03380-0
Source: Biotechnology Letters - May 6, 2023 Category: Biotechnology Authors: Rupal Ojha Satyendra Singh Nidhi Gupta Ketan Kumar Aditya K Padhi Vijay Kumar Prajapati Source Type: research
Immunization status of patients with spinal muscular atrophy receiving nusinersen therapy
CONCLUSION: Children with SMA had lower immunization rates and poor compliance with immunization programs. Clinicians should ensure that children with SMA receive the same preventive health measures as healthy children, including vaccinations.PMID:37147157 | DOI:10.1016/j.arcped.2023.03.006
Source: Archives de Pediatrie - May 5, 2023 Category: Pediatrics Authors: Mehmet Can Ye şilmen Çağatay Günay Gamze Sar ıkaya Uzan Özlem Özsoy Semra H ız Kurul Ulu ç Yiş Source Type: research
An evaluation of influenza, pneumococcal and herpes zoster vaccination coverage in Australian aged care residents, 2018 to 2022
CONCLUSIONS: Our study showed local influenza vaccination policies and practices exist and influenza vaccination uptake was consistently high. Pneumococcal and herpes zoster vaccination uptake were lower. Quality improvement strategies that at least determine the status of those residents classified as unknown are required.PMID:37147271 | DOI:10.1016/j.idh.2023.03.005
Source: Herpes - May 5, 2023 Category: Infectious Diseases Authors: Noleen Bennett Brett Morris Michael J Malloy Lyn-Li Lim Eliza Watson Ann Bull Janet Sluggett Leon J Worth NISPAC Advisory Group Source Type: research
