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Total 19535 results found since Jan 2013.
Use of a Person-Centered Narrative Intervention in an Outpatient Palliative Care Setting: A Feasibility Study
J Patient Exp. 2023 Sep 18;10:23743735231202729. doi: 10.1177/23743735231202729. eCollection 2023.ABSTRACTPerson-centered narrative interventions offer potential solutions to facilitate a connection between the person receiving care and the person delivering the care, to improve quality of care, and positively impact a patient's biopsychosocial well-being. This single-arm feasibility study investigates patient-reported outcomes and barriers/facilitators to the implementation of an all-virtually delivered person-centered narrative intervention into the person's electronic health record. Overall, electronic data collection f...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Heather Coats Nadia Shive C Robert Bennett Bonnie Adrian Andrew D Boyd Ardith Z Doorenbos Sarah J Schmiege Source Type: research
'Thank goodness you're here'. Exploring the impact on patients, family carers and staff of enhanced 7-day specialist palliative care services: A mixed methods study
CONCLUSIONS: Enhanced seven-day services provide high quality integrated palliative care, with positive experiences for patients, carers and staff.PMID:37731382 | DOI:10.1177/02692163231201486
Source: Palliative Medicine - September 21, 2023 Category: Palliative Care Authors: Catherine Walshe C éu Mateus Sandra Varey Steven Dodd Zoe Cockshott Lu ís Filipe Sarah G Brearley Source Type: research
Palliative care in colorectal and anal malignancies from diagnosis to death
This article will review the palliative needs of patients diagnosed with CRC and discuss how PC as a specialty is well poised to support these needs.PMID:37731305 | DOI:10.21037/apm-22-1390
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Mohana Karlekar Khaldoun Almhanna Dana Guyer Source Type: research
Neuroticism as a moderator of symptom-related distress and depression in 4 noncancer end-of-life populations
The objective of this study was to examine the impact of neuroticism as a moderator of physical symptoms and development of depression in patients with amyotrophic lateral sclerosis (ALS), chronic obstructive pulmonary disease (COPD), end-stage renal disease (ESRD), and frailty in the last 6 months of life.METHODS: We met this objective using secondary data collected in the Dignity and Distress across End-of-Life Populations study. The data included N = 404 patients with ALS (N = 101), COPD (N = 100), ESRD (N = 101), and frailty (N = 102) in the estimated last 6 months of life, with a range of illness-related symptoms, ass...
Source: Palliative and Supportive Care - September 21, 2023 Category: Palliative Care Authors: Maia S Kredentser Corey S Mackenzie Susan E McClement Murray W Enns Diane Hiebert-Murphy Dallas J Murphy Harvey M Chochinov Source Type: research
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
Eur J Med Chem. 2023 Sep 12;261:115803. doi: 10.1016/j.ejmech.2023.115803. Online ahead of print.ABSTRACTNeurodegenerative processes characterizing Alzheimer's disease (AD) are strictly related to the impairment of cholinergic and glutamatergic neurotransmitter systems which provoke synaptic loss. These experimental evidences still represent the foundation of the actual standard-of-care treatment for AD, albeit palliative, consisting on the coadministration of an acetylcholinesterase inhibitor and the NMDAR antagonist memantine. In looking for more effective treatments, we previously developed a series of galantamine-meman...
Source: European Journal of Medicinal Chemistry - September 21, 2023 Category: Chemistry Authors: Filippo Basagni Jose A Ortega Sine M Bertozzi Andrea Armirotti Maria Summa Rosalia Bertorelli Manuela Bartolini Ian R Mellor Martina Bedeschi Giovanni Bottegoni Vittorio Lembo Anna Minarini Andrea Cavalli Michela Rosini Source Type: research
Existential Care in Daily Nursing Practice
Am J Nurs. 2023 Oct 1;123(10):42-48. doi: 10.1097/01.NAJ.0000979092.39243.d4.ABSTRACTRelationship-centered palliative nursing during serious illness requires existential care. Yet, multilevel systemic barriers hinder nurses' ability to provide this care. The authors suggest ways to navigate these barriers, highlighting existential care priorities that nurses can attend to in their daily practice. These include 1) maintaining a strengths-based orientation, 2) taking a life course perspective, 3) grounding care firmly in relationships, and 4) responding moment to moment. They propose that by emphasizing existential care in p...
Source: The American Journal of Nursing - September 21, 2023 Category: Nursing Authors: Elise C Tarbi Elizabeth G Broden William E Rosa Adam Hayden Brianna E Morgan Source Type: research
Impact of Surgical Management for Relapse After Conversion Hepatectomy for Initially Unresectable Colorectal Liver Metastasis: A Retrospective Cohort Study
CONCLUSION: For IU-CRLM patients with liver relapse following conversion hepatectomy, the RLDT is essential for cure and prolonged survival. To avoid missing the opportunity for RLDT, intensive disease surveillance should be proposed.PMID:37730473 | DOI:10.1016/j.clcc.2023.08.007
Source: Clinical Colorectal Cancer - September 20, 2023 Category: Cancer & Oncology Authors: Yijiao Chen Dexiang Zhu Miao Chen Yuqiu Xu Qinghai Ye Xiaoying Wang Pingping Xu Qingyang Feng Meiling Ji Ye Wei Jia Fan Jianmin Xu Source Type: research
Targeted therapy and immunotherapy for orbital and periorbital tumors: a major review
This article will focus on recent updates in the application of available targeted and immunotherapy for managing orbital and periorbital tumors and tumor-like conditions, which include cutaneous basal cell carcinoma, cutaneous squamous cell carcinoma, cutaneous melanoma, Merkel cell carcinoma, sebaceous gland carcinoma, solitary fibrous tumor, dermatofibrosarcoma protuberans, orbital meningioma, neurofibromatosis, Langerhans cell histiocytosis, ocular adnexal lymphoma, orbital lymphatic malformation, and adenoid cystic carcinoma.PMID:37728602 | DOI:10.1080/01676830.2023.2256848
Source: Orbit - September 20, 2023 Category: Opthalmology Authors: Emmanuel Lee Boniao Richard C Allen Gangadhara Sundar Source Type: research
Complexity and function of family involvement in advance care planning: A qualitative study of perspectives from people living with advanced cancer, family members and healthcare professionals
CONCLUSIONS: Two mechanisms of how family involvement may enable goal-concordant care were identified: family members' support provision and their preparation for realising patients' wishes. Healthcare professionals should assess family's readiness to engage in advance care planning, and the time required to prepare them for the process.PMID:37723885 | DOI:10.1177/02692163231194202
Source: Palliative Medicine - September 19, 2023 Category: Palliative Care Authors: Megumi Kishino Jonathan Koffman Hiroaki Nagatomi Misuzu Yuasa Clare Ellis-Smith Source Type: research
Predicted and actual survival in palliative surgical oncology patients: Are surgeons overly optimistic?
Asian J Surg. 2023 Sep 16:S1015-9584(23)01470-7. doi: 10.1016/j.asjsur.2023.09.051. Online ahead of print.NO ABSTRACTPMID:37723038 | DOI:10.1016/j.asjsur.2023.09.051
Source: Asian Journal of Surgery - September 18, 2023 Category: Surgery Authors: Irene A T Ng Sasinthiran Thiagarajan Whee Sze Ong Si Min Jolene Wong Source Type: research
Clinical outcomes of conversion surgery following immune checkpoint inhibitors and chemotherapy in stage IV gastric cancer
CONCLUSIONS: Conversion surgery holds the potential for significant survival benefits in stage IV GC patients who have achieved a favorable clinical response to immunochemotherapy. Individuals with signet ring cell carcinoma may experience increased post-conversion surgery recurrence.PMID:37720943 | DOI:10.1097/JS9.0000000000000738
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Huayuan Liang Xiao Yan Xinhua Chen Zhiwei Li Yaopeng Qiu Fengping Li Minghao Wang Zhicheng Huang Kaihua Huang Qing Xie Huimin Zhang Guoxin Li Hao Liu Liying Zhao Source Type: research
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
