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Infectious Disease: Hepatitis

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Total 32368 results found since Jan 2013.

Drug-related adverse reactions in pediatric Inflammatory Bowel Disease
This article is protected by copyright. All rights reserved.PMID:37611322 | DOI:10.1002/jcph.2339
Source: The Journal of Clinical Pharmacology - August 23, 2023 Category: Drugs & Pharmacology Authors: Ana Losa Rita Gomes Francisco Ribeiro Mour ão Sandra Soares Cardoso Paula Manuel Vieira M ário Rui Correia Helena Moreira Silva Gisela Silva Marta Tavares Ermelinda Santos Silva Rosa Lima Source Type: research

Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis
CONCLUSION: MTX is a promising chemotherapeutic agent for β-catenin hyperactive liver cancer. Since repurposing MTX has the advantages of lower risk, shorter timelines, and less investment in drug discovery and development, a clinical trial is warranted to test its efficacy in the treatment of β-catenin mutant liver cancer.PMID:37612257 | DOI:10.1097/CM9.0000000000002816
Source: Chinese Medical Journal - August 23, 2023 Category: General Medicine Authors: Fangming Liu Yuting Wu Baohui Zhang Shuhui Yang Kezhuo Shang Jie Li Pengju Zhang Weiwei Deng Linlin Chen Liang Zheng Xiaochen Gai Hongbing Zhang Source Type: research

Rat Hepatitis E Virus in Norway Rats, Ontario, Canada, 2018-2021
Emerg Infect Dis. 2023 Sep;29(9):1890-1894. doi: 10.3201/eid2909.230517.ABSTRACTWe tested liver samples from 372 Norway rats (Rattus norvegicus) from southern Ontario, Canada, during 2018-2021 to investigate presence of hepatitis E virus infection. Overall, 21 (5.6%) rats tested positive for the virus. Sequence analysis demonstrated all infections to be rat hepatitis E virus (Rocahepevirus ratti genotype C1).PMID:37610234 | DOI:10.3201/eid2909.230517
Source: Emerging Infectious Diseases - August 23, 2023 Category: Infectious Diseases Authors: Sarah J Robinson Jamie Borlang Chelsea G Himsworth David L Pearl J Scott Weese Antonia Dibernardo Carla Osiowy Neda Nasheri Claire M Jardine Source Type: research

Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
CONCLUSION: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.PMID:37606856 | DOI:10.1007/s00262-023-03498-0
Source: Herpes - August 22, 2023 Category: Infectious Diseases Authors: C Schmitt E P Hoefsmit T Fangmeier N Kramer C Kabakci J Vera Gonz ález J M Versluis A Compter T Harrer H Mijo čević S Schubert T Hundsberger A M Menzies R A Scolyer G V Long L E French C U Blank L M Heinzerling Source Type: research

Serum Expression Level of MicroRNA-122 and its Significance in different Stages of Hepatitis B Virus Infection
This study aims to determine the serum expression level of miRNA-122 and its significance in the different stages of Hepatitis B virus infection. The study subjects were recruited and grouped for Hepatitis B associated with Chronic Hepatitis B infection, hepatic sclerosis, hepatocellular carcinoma, and healthy controls were also considered. Venous blood was collected from the participants including the controls and routine blood tests and quantification of miRNA-122 were done and analyzed in each case of hepatitis B infection and compared with that of healthy controls. The miRNA-122 was determined, which came to be highest...
Source: Mol Biol Cell - August 22, 2023 Category: Molecular Biology Authors: Shashi Prabha Singh Vandana Maurya Krishan Kumar Durgesh Singh Poonam Verma Dipan Samanta Manish Kumar Verma Source Type: research

The transmission of hepatitis B virus (HBV) infection from mother-to-infant (MTI) and the susceptibility of offspring to hepatitis B under intrauterine exposure to HBsAg
CONCLUSIONS: Therefore, we speculated that these signaling pathways and the genes within may be closely related to hepatitis B susceptibility and maternal hepatitis B inheritance. In this study, we showed that differentially expressed genes and signaling pathways may be valuable in preventing MTI transmission of HBV.PMID:37606146 | DOI:10.26355/eurrev_202308_33309
Source: Pharmacological Reviews - August 22, 2023 Category: Drugs & Pharmacology Authors: M-M Zhang X Liao H Wang Source Type: research

Sustained Virological Response Rates following Hepatitis C treatment with Direct-Acting Antivirals in patients
Ir Med J. 2023 Aug 17;116(7):813.NO ABSTRACTPMID:37606261
Source: Ir Med J - August 22, 2023 Category: General Medicine Authors: N Nurdin L Corey S O'Toole J Sopena-Falco D Houlihan E R Feeney Source Type: research

Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
CONCLUSION: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.PMID:37606856 | DOI:10.1007/s00262-023-03498-0
Source: Cancer Control - August 22, 2023 Category: Cancer & Oncology Authors: C Schmitt E P Hoefsmit T Fangmeier N Kramer C Kabakci J Vera Gonz ález J M Versluis A Compter T Harrer H Mijo čević S Schubert T Hundsberger A M Menzies R A Scolyer G V Long L E French C U Blank L M Heinzerling Source Type: research

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