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Infectious Disease: Hepatitis
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Total 32368 results found since Jan 2013.
Duck Hepatitis A virus: full-length genome-based phylogenetic and phylogeographic view during 1986-2020
Virus Res. 2023 Aug 30:199216. doi: 10.1016/j.virusres.2023.199216. Online ahead of print.ABSTRACTDuck hepatitis A virus (DHAV) is one of key pathogens for duck viral hepatitis, especially in Asian duck industry. Currently, two main genotypes (DHAV-1 and -3) exist. To explore insightfully the evolutionary character, we assessed the available 141 full-length genome sequences of DHAV isolated in 1986-2020 globally and divided DHAV-1 and DHAV-3 into further seven (DHAV-1 a-g) and five (DHAV-3 a-e) sub-clades, respectively. Phylogenetic and phylogeographic network analyses indicated great genetic diversity of DHAV identified i...
Source: Virus Research - September 1, 2023 Category: Virology Authors: Caiting Yang Pir Tariq Shah Amina Nawal Bahoussi Changxin Wu Li Wang Li Xing Source Type: research
Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma
Curr Cancer Drug Targets. 2023;23(11):879-888. doi: 10.2174/1568009623666230503094346.ABSTRACTOne of the most important health problems in the world today is cancer. The World Health Organization (WHO) reported that it results in 8.9 million deaths annually. Malignant tumours and unregulated cell proliferation are features of malignant neoplasms, which can also invade nearby body regions. Hepatocellular carcinoma is the third most prevalent cause of cancer-related death worldwide and the fifth most common kind of cancer, according to a recent analysis. Patients with liver disease as well as chronic hepatitis B and C are mo...
Source: Current Cancer Drug Targets - September 1, 2023 Category: Cancer & Oncology Authors: Amrita Singh Sudhanshu Mishra Saurabh Sharma Smriti Ojha Sunil Yagnik Sudhi Pandey Source Type: research
Duck Hepatitis A virus: full-length genome-based phylogenetic and phylogeographic view during 1986-2020
Virus Res. 2023 Aug 30:199216. doi: 10.1016/j.virusres.2023.199216. Online ahead of print.ABSTRACTDuck hepatitis A virus (DHAV) is one of key pathogens for duck viral hepatitis, especially in Asian duck industry. Currently, two main genotypes (DHAV-1 and -3) exist. To explore insightfully the evolutionary character, we assessed the available 141 full-length genome sequences of DHAV isolated in 1986-2020 globally and divided DHAV-1 and DHAV-3 into further seven (DHAV-1 a-g) and five (DHAV-3 a-e) sub-clades, respectively. Phylogenetic and phylogeographic network analyses indicated great genetic diversity of DHAV identified i...
Source: Virus Research - September 1, 2023 Category: Virology Authors: Caiting Yang Pir Tariq Shah Amina Nawal Bahoussi Changxin Wu Li Wang Li Xing Source Type: research
Etiology and clinical characteristics of acute viral hepatitis in South Korea during 2020-2021: a prospective multicenter study
Sci Rep. 2023 Aug 31;13(1):14271. doi: 10.1038/s41598-023-40775-5.ABSTRACTThis prospective, 12-center study investigated the etiology and clinical characteristics of acute viral hepatitis (AVH) during 2020-2021 in South Korea, and the performance of different diagnostic methods for hepatitis E virus (HEV). We enrolled 428 patients with acute hepatitis, of whom 160 (37.4%) were diagnosed with AVH according to predefined serologic criteria. The clinical data and risk factors for AVH were analyzed. For hepatitis E patients, anti-HEV IgM and IgG were tested with two commercial ELISA kits (Abia and Wantai) with HEV-RNA real-tim...
Source: Herpes - August 31, 2023 Category: Infectious Diseases Authors: Chan Young Jeong Gwang Hyeon Choi Eun Sun Jang Young Seok Kim Youn-Jae Lee In Hee Kim Sung Bum Cho Jae Hyun Yoon Kyung-Ah Kim Dae Hee Choi Woo Jin Chung Hyun-Jin Cho Seong Kyun Na Yun-Tae Kim Byung Seok Lee Sook-Hyang Jeong Source Type: research
An alarming surge of scrub typhus cases presenting as acute encephalitis in children
We present four cases of scrub typhus with acute encephalitis, including one with multiorgan failure and another serologically proven co-infection with Hepatitis C. Treatment of scrub typhus is not, however, so difficult, so its early diagnosis is paramount.PMID:37644872 | DOI:10.1177/00494755231194197
Source: Tropical Doctor - August 30, 2023 Category: Tropical Medicine Authors: Uneza Husain None Arpita Raj Kumar Kalyan Source Type: research
Survey of blood collection and transfusion practices among institutions in Africa
This study highlights significant variability and restrictions in blood product availability, pre-transfusion testing, and blood donor infectious disease testing across Africa. Further studies are needed to ascertain barriers to improving blood donor availability, blood product safety, and infectious disease testing.PMID:37646070 | DOI:10.1111/trf.17501
Source: Transfusion - August 30, 2023 Category: Hematology Authors: Jeremy W Jacobs Laura D Stephens Danny A Milner Evan M Bloch Ruchika Goel Aaron A R Tobian Aaron Lunda Shibemba Quentin Eichbaum Vanderbilt Pathology Program in Global Health (VPPIGH) Source Type: research
Seroprevalence of Hepatitis C Virus Infection in North Korean Defectors Residing in Korea
CONCLUSION: This is the first prospective study to investigate the prevalence rate of HCV infection among North Korean defectors residing in South Korea. As North Korean defectors are a vulnerable group concerning HCV infection, they may benefit from HCV screening policies and educational interventions for HCV infection.PMID:37644684 | DOI:10.3346/jkms.2023.38.e270
Source: J Korean Med Sci - August 30, 2023 Category: General Medicine Authors: Young Mi Hong Ki Tae Yoon Young Joo Park Hyun Young Woo Jeong Heo Source Type: research
Arbidol: The current demand, strategies, and antiviral mechanisms
CONCLUSION: ARB is a broad-spectrum antiviral drug that inhibits several viruses in vivo and in vitro, with high safety profile and low resistance; the antiviral mechanisms of ARB deserve to be further explored and more high-quality clinical studies are required to establish the efficacy and safety of ARB.PMID:37647451 | DOI:10.1002/iid3.984
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Yue Kang Yin Shi Silu Xu Source Type: research
Seroprevalence of Hepatitis C Virus Infection in North Korean Defectors Residing in Korea
CONCLUSION: This is the first prospective study to investigate the prevalence rate of HCV infection among North Korean defectors residing in South Korea. As North Korean defectors are a vulnerable group concerning HCV infection, they may benefit from HCV screening policies and educational interventions for HCV infection.PMID:37644684 | DOI:10.3346/jkms.2023.38.e270
Source: J Korean Med Sci - August 30, 2023 Category: General Medicine Authors: Young Mi Hong Ki Tae Yoon Young Joo Park Hyun Young Woo Jeong Heo Source Type: research
Arbidol: The current demand, strategies, and antiviral mechanisms
CONCLUSION: ARB is a broad-spectrum antiviral drug that inhibits several viruses in vivo and in vitro, with high safety profile and low resistance; the antiviral mechanisms of ARB deserve to be further explored and more high-quality clinical studies are required to establish the efficacy and safety of ARB.PMID:37647451 | DOI:10.1002/iid3.984
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Yue Kang Yin Shi Silu Xu Source Type: research
Survey of blood collection and transfusion practices among institutions in Africa
This study highlights significant variability and restrictions in blood product availability, pre-transfusion testing, and blood donor infectious disease testing across Africa. Further studies are needed to ascertain barriers to improving blood donor availability, blood product safety, and infectious disease testing.PMID:37646070 | DOI:10.1111/trf.17501
Source: Transfusion - August 30, 2023 Category: Hematology Authors: Jeremy W Jacobs Laura D Stephens Danny A Milner Evan M Bloch Ruchika Goel Aaron A R Tobian Aaron Lunda Shibemba Quentin Eichbaum Vanderbilt Pathology Program in Global Health (VPPIGH) Source Type: research
