Filtered By:
Countries: Saudi Arabia Health

This page shows you your search results in order of date. This is page number 13.

Order by Relevance | Date

Total 30568 results found since Jan 2013.

Marine-derived sea urchin compounds as potential anti-cancer drug candidate against colorectal cancer: < em > In silico and in vitro < /em > studies
In this study, 19 compounds derived from sea urchin (Diadema savignyi) were used to treat colorectal cancer using the HCT116 cell line. However, molecular docking, ADME (absorption, distribution, metabolism, and excretion), toxicity, molecular dynamic (MD) simulation, and molecular mechanics generalized Born surface area (MM-GBSA) were used to confirm the ligand-protein interaction. Interactions of Importin-11 receptor with sea urchin compounds reveal that four compounds have higher binding affinities (ranging from -8.6 to -7.1 kcal/mol). In vitro testing revealed that the CID 6432458 compound was effective (docking score ...
Source: Mol Biol Cell - August 10, 2023 Category: Molecular Biology Authors: Mohammad Habibur Rahman Molla Mohammed Othman Aljahdali Source Type: research

Effect of infection with severe acute respiratory syndrome coronavirus 2 on the fetus in pregnant women who recovered from infection
CONCLUSION: Maternal SARS-CoV-2 infection during pregnancy was associated with a higher prevalence of small for gestational age (SGA) fetuses.LIMITATIONS: Retrospective, middle cerebral artery and uterine artery Doppler data were not included nor were the effect of tobacco use and socioeconomic status, the relationship between the date of infection with the date of conceiving or the relationship between the severity of infection in the mother and fetal biometry and growth.CONFLICT OF INTEREST: None.PMID:37554020 | DOI:10.5144/0256-4947.2023.213
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Lina Fahmi Hammad Ahad Naif Almutairi Rana Hussain Aldahlawi Source Type: research

Investigation of the Radiographic Imaging Volume and Occupational Dose of Radiologic Technologists before and during the COVID-19 Pandemic
This study aimed to assess occupational radiation doses for radiologic technologists (RTs) in Saudi Arabia shortly before and during the COVID-19 pandemic, considering changes in imaging volume during that time. This retrospective study included the imaging volume data and the RTs' occupational dose records from a central hospital for 2019 and 2020. The occupational dose-in terms of annual and quarterly mean effective doses (AMEDs and QMEDs)-was estimated for 115 RTs using thermoluminescent dosimeter records. There was a 22% increase in the AMED in 2020 compared with 2019, though the overall imaging volume decreased by 9% ...
Source: Health Physics - August 7, 2023 Category: Physics Authors: Nasser Shubayr Source Type: research

Long-running ProMED email service for alerting world to disease outbreaks is in trouble
The first news about the COVID-19 pandemic came not from a government or a scientific publication, but in an email from a disease-alert system called ProMED . This fateful missive in December 2019 about a few cases of a mysterious pneumonia in Wuhan, China, is just one example of how physicians and public health experts around the world have used the 30-year-old, free service to share real-time information about local disease outbreaks with tens of thousands of subscribers. But ProMED is now on life support. Much of its work came to a screeching halt yesterday when 21 of its 38 paid editors and moderators went o...
Source: Science of Aging Knowledge Environment - August 4, 2023 Category: Geriatrics Source Type: research

The cytological pattern of cervical smears of a series of Saudi women in one gynecologic center
CONCLUSIONS: The prevalence of CIN has been growing in Saudi Arabia in recent years, implying a probable involvement in the spread of HPV. Most CIN cases associated with middle age point to HPV infection at a younger age. There is no link between estrogen and/or progesterone levels and CIN.PMID:37522689 | DOI:10.26355/eurrev_202307_33149
Source: Pharmacological Reviews - July 31, 2023 Category: Drugs & Pharmacology Authors: S A Alharbi F D Alshammari M I Humaida E K Abdalhabib M A Babikir Bealy A E O Elkhalifa A A Agabeldour F F Alshammari Source Type: research

Role of single nucleotide polymorphism rs2383206 on coronary artery disease risk among Saudi Population: a case-control study
CONCLUSIONS: In conclusion, this study demonstrated a significant association between the rs2383206 variant located on chromosome 9p21 and the development of CAD. The findings of this study provide valuable insights into the genetic susceptibility to CAD and highlight the potential of this variant as a target for future functional studies.PMID:37522678 | DOI:10.26355/eurrev_202307_33137
Source: Pharmacological Reviews - July 31, 2023 Category: Drugs & Pharmacology Authors: N M Bogari R M Allam A Dannoun M Athar A Bouazzaoui O Elkhateeb M Porqueddu S A Amer A Elsayed G I Colombo Source Type: research

Short Tandem Repeat (STR) Profiling of Earwax DNA Obtained from Healthy Volunteers
Curr Issues Mol Biol. 2023 Jul 10;45(7):5741-5751. doi: 10.3390/cimb45070362.ABSTRACTThe present study aimed to establish human earwax as a potential source of DNA evidence that could be effectively used in human identification. Sixty earwax samples were obtained from 15 healthy male and female Saudi volunteers living in Riyadh, Saudi Arabia. Four consecutive earwax swab samples were obtained from each volunteer and stored for 1, 15, 30 and 60 days. Earwax samples were stored at room temperature (20-22 °C). Reference oral swab was also taken from each volunteer. DNA was extracted by QIAamp DNA Mini kit and quantified by r...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Sayed Amin Amer Maha Nawar Alotaibi Sajjad Shahid Mahmoud Alsafrani Abdul Rauf Chaudhary Source Type: research

Molecular Role of Asn680Ser and Asp37Glu Missense Variants in Saudi Women with Female Infertility and Polycystic Ovarian Syndrome
In conclusion, rs6166 and rs2296545 SNPs were not associated with FI or PCOS in Saudi women.PMID:37504264 | PMC:PMC10378235 | DOI:10.3390/cimb45070348
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Amal F Alshammary Sarah F Alsobaie Arwa A Alageel Fahad M Aldakheel Sabah Ansar Reem Alrashoudi Raed Farzan Norah A Alturki Maysoon Abdulhadi Alhaizan Johara Al-Mutawa Imran Ali Khan Source Type: research

Short Tandem Repeat (STR) Profiling of Earwax DNA Obtained from Healthy Volunteers
Curr Issues Mol Biol. 2023 Jul 10;45(7):5741-5751. doi: 10.3390/cimb45070362.ABSTRACTThe present study aimed to establish human earwax as a potential source of DNA evidence that could be effectively used in human identification. Sixty earwax samples were obtained from 15 healthy male and female Saudi volunteers living in Riyadh, Saudi Arabia. Four consecutive earwax swab samples were obtained from each volunteer and stored for 1, 15, 30 and 60 days. Earwax samples were stored at room temperature (20-22 °C). Reference oral swab was also taken from each volunteer. DNA was extracted by QIAamp DNA Mini kit and quantified by r...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Sayed Amin Amer Maha Nawar Alotaibi Sajjad Shahid Mahmoud Alsafrani Abdul Rauf Chaudhary Source Type: research

Molecular Role of Asn680Ser and Asp37Glu Missense Variants in Saudi Women with Female Infertility and Polycystic Ovarian Syndrome
In conclusion, rs6166 and rs2296545 SNPs were not associated with FI or PCOS in Saudi women.PMID:37504264 | PMC:PMC10378235 | DOI:10.3390/cimb45070348
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Amal F Alshammary Sarah F Alsobaie Arwa A Alageel Fahad M Aldakheel Sabah Ansar Reem Alrashoudi Raed Farzan Norah A Alturki Maysoon Abdulhadi Alhaizan Johara Al-Mutawa Imran Ali Khan Source Type: research

Short Tandem Repeat (STR) Profiling of Earwax DNA Obtained from Healthy Volunteers
Curr Issues Mol Biol. 2023 Jul 10;45(7):5741-5751. doi: 10.3390/cimb45070362.ABSTRACTThe present study aimed to establish human earwax as a potential source of DNA evidence that could be effectively used in human identification. Sixty earwax samples were obtained from 15 healthy male and female Saudi volunteers living in Riyadh, Saudi Arabia. Four consecutive earwax swab samples were obtained from each volunteer and stored for 1, 15, 30 and 60 days. Earwax samples were stored at room temperature (20-22 °C). Reference oral swab was also taken from each volunteer. DNA was extracted by QIAamp DNA Mini kit and quantified by r...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Sayed Amin Amer Maha Nawar Alotaibi Sajjad Shahid Mahmoud Alsafrani Abdul Rauf Chaudhary Source Type: research

Molecular Role of Asn680Ser and Asp37Glu Missense Variants in Saudi Women with Female Infertility and Polycystic Ovarian Syndrome
In conclusion, rs6166 and rs2296545 SNPs were not associated with FI or PCOS in Saudi women.PMID:37504264 | DOI:10.3390/cimb45070348
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Amal F Alshammary Sarah F Alsobaie Arwa A Alageel Fahad M Aldakheel Sabah Ansar Reem Alrashoudi Raed Farzan Norah A Alturki Maysoon Abdulhadi Alhaizan Johara Al-Mutawa Imran Ali Khan Source Type: research