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Infectious Disease: Hepatitis

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Question: Is breastfeeding useful in the management of neonatal abstinence syndrome?
Case scenario A 23-year-old woman is admitted to the postnatal ward after she gave birth to a term infant of 3 kg. During pregnancy, she is known to have used methadone. There is no known use of other illicit drugs or prescription medication. The midwife who is taking care of this woman and her baby asks if she can encourage the mother to breastfeed her child. Structured clinical question Can a mother who used methadone during pregnancy (patient) breastfeed her newborn (intervention) to help the management of neonatal abstinence syndrome (NAS) (outcome)? Search Search strategy: terms used: Breastfeeding AND neonatal a...
Source: Archives of Disease in Childhood - March 17, 2015 Category: Pediatrics Authors: Lefevere, J., Allegaert, K. Tags: ADC Archimedes, Liver disease, Immunology (including allergy), Hepatitis and other GI infections, HIV/AIDS, Childhood nutrition, Pregnancy, Reproductive medicine, Child health, Infant health, Infant nutrition (including breastfeeding), Neonatal health, Un Source Type: research

Effect of IMB Model Combined with Spousal Support Breastfeeding Intervention on PBSES Score and Breastfeeding Rate of Primipara with Chronic Hepatitis B Virus Infection
CONCLUSION: The self-efficacy of prenatal breastfeeding in pregnant women with HBV is low, and the application of the IMB model combined with the intervention mode of spy-supported breastfeeding has positive effects on the improvement of maternal breastfeeding efficiency, breastfeeding health knowledge level, and postpartum breastfeeding rate, which is worthy of clinical promotion and application.PMID:36158886 | PMC:PMC9499791 | DOI:10.1155/2022/9661408
Source: Biomed Res - September 26, 2022 Category: Research Authors: Shaoping Chen Linxian Li Qianwen Sun Shulan Chen Jing Cheng Siqi Xiong Source Type: research

Travel Characteristics and Pretravel Health Care Among Pregnant or Breastfeeding U.S. Women Preparing for International Travel.
CONCLUSION: Most pregnant and breastfeeding travelers seen for pretravel health consultations traveled to destinations with high risk for vector-borne or other travel-related diseases. Destination-specific preventive interventions were frequently underused. PMID: 29112671 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - November 3, 2017 Category: OBGYN Authors: Hagmann SHF, Rao SR, LaRocque RC, Erskine S, Jentes ES, Walker AT, Barnett ED, Chen LH, Hamer DH, Ryan ET, Global TravEpiNet Consortium and the Boston Area Travel Medicine Network Tags: Obstet Gynecol Source Type: research

Extended pre-exposure prophylaxis with lopinavir–ritonavir versus lamivudine to prevent HIV-1 transmission through breastfeeding up to 50 weeks in infants in Africa (ANRS 12174): a randomised controlled trial
Publication date: Available online 19 November 2015 Source:The Lancet Author(s): Nicolas Nagot, Chipepo Kankasa, James K Tumwine, Nicolas Meda, G Justus Hofmeyr, Roselyne Vallo, Mwiya Mwiya, Mary Kwagala, Hugues Traore, Amwe Sunday, Mandisa Singata, Chafye Siuluta, Eric Some, David Rutagwera, Desire Neboua, Grace Ndeezi, Debra Jackson, Valérie Maréchal, Dorine Neveu, Ingunn M S Engebretsen, Carl Lombard, Stéphane Blanche, Halvor Sommerfelt, Claire Rekacewicz, Thorkild Tylleskär, Philippe Van de Perre Background Strategies to prevent postnatal mother-to-child transmission of HIV-1 in Africa, ...
Source: The Lancet - November 21, 2015 Category: Journals (General) Source Type: research

Breastfeeding While Taking Lamivudine or Tenofovir Disoproxil Fumarate: A Review of the Evidence
Lamivudine and tenofovir disoproxil fumarate (TDF) are both active against hepatitis B virus (HBV). Due to its potency, high genetic barrier to resistance, and safety during pregnancy, TDF may be useful to prevent HBV transmission from mother to child, which is the leading cause of transmission globally. Despite the safety record of lamivudine and TDF in pregnancy, the labels for both of these drugs recommend against their use during breastfeeding. In this review, we discuss the data regarding lamivudine and TDF use during pregnancy and breastfeeding and find that the exposure to the drug is lower from breastfeeding than f...
Source: Clinical Infectious Diseases - December 23, 2014 Category: Infectious Diseases Authors: Ehrhardt, S., Xie, C., Guo, N., Nelson, K., Thio, C. L. Tags: VIRAL HEPATITIS Source Type: research

Hepatitis B virus mother‐to‐child transmission among HIV‐infected women receiving lamivudine‐containing antiretroviral regimens during pregnancy and breastfeeding
Summary The study included 309 HIV‐infected pregnant women receiving a lamivudine‐containing antiretroviral regimen from week 25 of gestational age until 6 months postpartum, during breastfeeding. Twenty‐seven of them (8.7%) were hepatitis B virus surface antigen (HBsAg) positive; at baseline, hepatitis B virus (HBV) DNA levels >3 log10 IU/mL (with a median level of 6.2 log10 IU/mL) were found in 10 women, who at one, three and six months postpartum had median levels of 5.2 log10 IU/mL, 4.5 log10 IU/mL and 2.8 log10 IU/mL, respectively. Twenty‐four of the 30 breast milk samples evaluated had undetectable H...
Source: Journal of Viral Hepatitis - September 1, 2014 Category: Infectious Diseases Authors: M. F. Pirillo, P. Scarcella, M. Andreotti, H. Jere, E. Buonomo, J.‐B. Sagno, R. Amici, M. G. Mancini, P. Leone, S. Ceffa, S. Mancinelli, M. C. Marazzi, S. Vella, L. Palombi, M. Giuliano Tags: Original Article Source Type: research

Breastfeeding initiation among people with hepatitis C during pregnancy: associated factors and offspring outcomes
To identify factors associated with breastfeeding initiation and to assess the relationship between breastfeeding and offspring outcomes among people with hepatitis C virus (HCV) during pregnancy
Source: American Journal of Obstetrics and Gynecology - January 1, 2023 Category: OBGYN Authors: Jennifer L. Grasch Tags: Poster Session III Source Type: research

Breastfeeding and pain relief in full-term neonates during immunization injections: a clinical randomized trial
Background: The aim of this study was to examine the effect of breastfeeding on pain relief in full-term neonates during injection of hepatitis B vaccine. Methods: This was a randomized clinical trial. A sample of full-term neonates was randomly allocated into two groups: the experimental group and the control group. Neonates in the experimental group were breastfed two minutes before, during, and after the hepatitis B immunization and the control group were held in mothers' arms but not fed. Pain was assessed using the Douleur Aigue du Nouveau-ne (DAN) scale measuring facial expressions, limb movements and vocal expressio...
Source: BMC Anesthesiology - September 13, 2013 Category: Anesthesiology Authors: Maryam ModarresAzam JazayeriParvin RahnamaAli Montazeri Source Type: research

Drugs for Hepatitis
Breastfeeding Medicine , Vol. 0, No. 0.
Source: Breastfeeding Medicine - August 4, 2016 Category: Perinatology & Neonatology Authors: Philip O. Anderson Source Type: research

SemEHR: A general-purpose semantic search system to surface semantic data from clinical notes for tailored care, trial recruitment, and clinical research*
ConclusionResults from the multiple case studies demonstrate SemEHR ’s efficiency: weeks or months of work can be done within hours or minutes in some cases. SemEHR provides a more comprehensive view of patients, bringing in more and unexpected insight compared to study-oriented bespoke IE systems. SemEHR is open source, available athttps://github.com/CogStack/SemEHR.
Source: Journal of the American Medical Informatics Association - January 19, 2018 Category: Information Technology Source Type: research

Active search for hepatitis C patients in Primary Care
CONCLUSIONS: Active search for patients with hepatitis C in PC together with the OSD are effective measures to detect hidden infections and to increase the number of treatments, contributing to the elimination of hepatitis C.PMID:34284593 | DOI:10.17235/reed.2021.8067/2021
Source: Revista Espanola de Enfermedades Digestivas - July 21, 2021 Category: Gastroenterology Authors: Luc ía Seoane Blanco Javier Soto S ánchez Gema Sierra Dorado Leire Parapar Álvarez Manuel Crespo S ánchez Luis S ánchez Domínguez Juan de la Vega Fern ández Source Type: research

Routine childhood vaccination programme coverage, El Salvador, 2011-In search of timeliness.
Abstract While assessing immunization programmes, not only vaccination coverage is important, but also timely receipt of vaccines. We estimated both vaccination coverage and timeliness, as well as reasons for non-vaccination, and identified predictors of delayed or missed vaccination, for vaccines of the first two years of age, in El Salvador. We conducted a cluster survey among children aged 23-59 months. Caregivers were interviewed about the child immunization status and their attitudes towards immunization. Vaccination dates were obtained from children immunization cards at home or at health facilities. We refe...
Source: Vaccine - December 3, 2013 Category: Allergy & Immunology Authors: Suárez-Castaneda E, Pezzoli L, Elas M, Baltrons R, Crespin-Elías EO, Pleitez OA, de Campos MI, Danovaro-Holliday MC Tags: Vaccine Source Type: research

Search for a cure for chronic hepatitis B infection: How close are we?
Authors: Phyo WW, Soh AY, Lim SG, Lee GH Abstract Chronic hepatitis B (CHB) remains a significant unmet medical need, with 240 million chronically infected persons worldwide. It can be controlled effectively with either nucleoside/nucleotide-based or interferon-based therapies. However, most patients receiving these therapies will relapse after treatment withdrawal. During recent years, the advances in molecular biology and immunology have enabled a better understanding of the viral-host interaction and inspired new treatment approaches to achieve either elimination of the virus from the liver or durable immune con...
Source: World Journal of Hepatology - May 30, 2015 Category: Gastroenterology Tags: World J Hepatol Source Type: research