Filtered By:
Therapy: Chemotherapy
This page shows you your search results in order of date. This is page number 9.
Order by Relevance | Date
Total 472 results found since Jan 2013.
Eugenol: A New Option in Combination Therapy with Sorafenib for the Treatment of Undifferentiated Thyroid Cancer
This study investigated whether eugenol in combination with sorafenib was more effective than either substance individually in triggering apoptosis in the UTC. The IC50 of sorafenib and eugenol was determined in a UTC cell line (8305C) by MTT assay, and their synergistic effect in combination therapy was investigated. Flow cytometry was used to evaluate the rate of apoptosis in treated cells. To confirm that cell death occurred through apoptosis, immunoblotting was used to determine the relative cleavage of caspase-8 and caspase-9. The IC50 of sorafenib was 20 µM, and that of eugenol was 2100 µM. The sorafenib-eugenol co...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 13, 2022 Category: Allergy & Immunology Authors: Pedram Talezadeh Shirazi Shirin Farjadian Mohammad Hossein Dabbaghmanesh Hossein Jonaidi Ali Alavianmehr Mehdi Kalani Ladan Emadi Source Type: research
