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Therapy: Pain Management

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Total 331 results found since Jan 2013.

Comparison of ropivacaine, bupivacaine, prilocaine, and lidocaine in the management of pain and hemorrhage during nasal pack removal.
CONCLUSION: Topical lidocaine application before removal of nasal packs in patients who undergo nasal septal surgery can decrease discomfort and bleeding and improve patient tolerance. PMID: 24119607 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Gencer ZK, Ozkiriş M, Gencer M, Saydam L Tags: Am J Rhinol Allergy Source Type: research

Design, Synthesis and In Vitro Release Studies of Co-drugs for Rheumatoid Arthritis.
Abstract Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic, systemic inflammation that may affect many tissues and organs, but principally the synovial joints. The tendency for joint destruction is greatest in the early stages of disease hence current trend is to introduce a disease-modifying anti-rheumatic drug (DMARD) immediately after the diagnosis of RA in a step- up approach which is generally followed by its combination with a corticosteroid or NSAID. DMARD suppresses inflammatory activity over a long time-frame thus improving day to day function, and also prevents, lessens or dela...
Source: Inflammation and Allergy Drug Targets - December 1, 2015 Category: Allergy & Immunology Authors: Kashmira P, Suneela D, Shakuntalah C, Poorvashree J Tags: Inflamm Allergy Drug Targets Source Type: research

Efficacy and safety of bupivacaine versus lidocaine in local anaesthesia of the nasopharynx: A meta-analysis.
CONCLUSION: Bupivacaine was found to have better promotion to pain control than did lidocaine for the patients after nasal surgery. Lidocaine had a significantly increased inhibition of bleeding in these postoperative patients; however, the efficacy between bupivacaine and lidocaine was unclear for the patients who had transnasal endoscopic examinations. PMID: 27368150 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - June 29, 2016 Category: ENT & OMF Authors: Yu X, Wang J, Huang L, Yu X, He Z Tags: Am J Rhinol Allergy Source Type: research

Surgical treatment of chronic rhinosinusitis after sinus lift.
CONCLUSION: Functional endoscopic sinus surgery was a reasonable and efficacious treatment option for patients who presented with paranasal sinus disease after a sinus lift. Dental implant removal may not be a requirement for successful treatment of CRS associated with sinus lift procedures. PMID: 28716179 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2017 Category: ENT & OMF Authors: Jiam NT, Goldberg AN, Murr AH, Pletcher SD Tags: Am J Rhinol Allergy Source Type: research

Herpes labialis: An Update.
CONCLUSION: For episodic treatment, oral antiviral agents, such as acyclovir (Zovirax), valacyclovir (Valtrex) and famciclovir (Famvir), are superior to topical antiviral therapy. Valacyclovir and famciclovir have greater oral bioavailability and are better absorbed than acyclovir, require less frequent dosing, but are more expensive and are not approved for children. Topical antiviral agents such as 5% acyclovir cream/ointment (Zovirax) ± hydrocortisone (Xerese), 1% penciclovir (Denavir) cream, and 50 mg Buccal Adhesive Tablet (ABT-50 mg) can also be used for episodic treatment of herpes labialis. These topical agents ar...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - October 5, 2017 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Headaches and facial pain in rhinology.
Abstract "Sinus headache" is a common chief complaint that often leads patients to an otolaryngologist's office. Because facial pain may or may not be sinogenic in origin, the otolaryngologist should be equipped to evaluate and treat or to appropriately refer these patients. Analysis of current data indicates that the majority of patients who present with sinus headaches actually have migraines. Furthermore, the downstream effect of the cytokine cascade initiated in migraine physiology can cause rhinologic symptoms, including rhinorrhea, congestion, and lacrimation, which may also confound diagnosis. Other causes ...
Source: American Journal of Rhinology and Allergy - January 1, 2018 Category: ENT & OMF Authors: Jayawardena ADL, Chandra R Tags: Am J Rhinol Allergy Source Type: research

Urinary Tract Infection in Children.
CONCLUSION: Currently, a second or third generation cephalosporin and amoxicillin-clavulanate are drugs of choice in the treatment of acute uncomplicated UTI. Parenteral antibiotic therapy is recommended for infants ≤ 2 months, and any child who is toxic-looking, hemodynamically unstable, immunocompromised, unable to tolerate oral medication, or not responding to oral medication. A combination of intravenous ampicillin and intravenous/intramuscular gentamycin or a third-generation cephalosporin can be used in those situations. Routine antimicrobial prophylaxis is rarely justified, but continuous antimicrobial prophylaxis...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - December 31, 2018 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Surgical Approach to Frontal Sinus Osteoma: A Systematic Review.
CONCLUSION: Despite the increasing use of endoscopic alone procedures for expanding indications, patients may still require an open or endoscopic assisted approach for complete removal. PMID: 30950282 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - April 4, 2019 Category: ENT & OMF Authors: Watley DC, Mong ER, Rana NA, Illing EA, Chaaban MR Tags: Am J Rhinol Allergy Source Type: research

Acute Myocarditis in Children: An Overview of Treatment and Recent Patents.
CONCLUSIONS: This article reviews the current literature regarding etiology, clinical manifestations, diagnosis, and management of acute myocarditis in children. PMID: 32013855 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - February 6, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Effectiveness Comparison of Dexmedetomidine and Remifentanil for Perioperative Management in Patients Undergoing Endoscopic Sinus Surgery.
CONCLUSION: Dexmedetomidine had better postoperative sedative and analgesic effects than remifentanil for patients undergoing endoscopic sinus surgery in this study. Remifentanil and dexmedetomidine attenuated acute hemodynamic responses to be within normal ranges after intranasal injection of epinephrine, and no significant differences in terms of hemodynamic variables. Remifentanil was superior to dexmedetomidine in inducing hypotension during endotracheal intubation. PMID: 32438817 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - May 20, 2020 Category: ENT & OMF Authors: Huh H, Park JJ, Seong HY, Lee SH, Yoon SZ, Cho JE Tags: Am J Rhinol Allergy Source Type: research

Long-term Safety and Efficacy of Subcutaneous C1-Inhibitor in Older Patients With Hereditary Angioedema.
CONCLUSION: C1-INH (SC) was well tolerated and effective in the management of HAE in these subjects ≥65 years old with multiple comorbid conditions and polypharmacy. PMID: 32445670 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 19, 2020 Category: Allergy & Immunology Authors: Bernstein JA, Schwartz L, Yang W, Baker J, Anderson J, Farkas H, Aygören-Pürsün E, Bygum A, Jacobs I, Feuersenger H, Pragst I, Riedl MA Tags: Ann Allergy Asthma Immunol Source Type: research

Effect of Dextrose Prolotherapy, Platelet Rich Plasma and Autologous Conditioned Serum on Knee Osteoarthritis: A Randomized Clinical Trial.
In this study, the clinical efficiency of Dextrose prolotherapy, platelet-rich plasma (PRP) and autologous conditioned serum (ACS) injection on the level of pain and function in Knee OA were compared. A randomized clinical trial was directed on 92 knee OA patients. Patients were randomly divided into three groups: 30 were received dextrose prolotherapy once in a week for three weeks, 30 received autologous PRP for two times with seven days interval, and in the remaining 32 patients 2ml of ACS were injected two times every seven days. Study participants were measured through the Western Ontario and McMaster Universities (WO...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 22, 2020 Category: Allergy & Immunology Authors: Pishgahi A, Abolhasan R, Shakouri SK, Soltani-Zangbar MS, Dareshiri S, Ranjbar Kiyakalayeh S, Khoeilar A, Zamani M, Motavalli Khiavi F, Pourabbas Kheiraddin B, Mehdizadeh A, Yousefi M Tags: Iran J Allergy Asthma Immunol Source Type: research

Human Ascariasis: An Updated Review.
CONCLUSION: The average cure rate with anthelminthic treatment is over 95%. Unfortunately, most treated patients in endemic areas become re-infected within months. Health education, personal hygiene, improved sanitary conditions, proper disposal of human excreta, and discontinuing the use of human fecal matter as a fertilizer are effective long-term preventive measures. Targeting deworming treatment and mass anthelminthic treatment should be considered in regions where A. lumbricoides is prevalent. PMID: 32628606 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - July 7, 2020 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Metal Allergy as a Cause of Implant Failure in Shoulder Arthroplasty.
Abstract Metal allergy is an uncommon and poorly understood cause of failure of orthopedic implants. To the authors' knowledge, there have been no reports of the management of shoulder arthroplasty patients with metal allergy. The authors present their experience with the diagnosis and management of patients with metal allergy. Patients with metal allergy undergoing shoulder arthroplasty were identified through retrospective chart review from January 1, 2012, to January 31, 2015. Case characteristics collected included patient risk factors (age, sex, prior cutaneous reactions to metal), metal allergy factors (type...
Source: Orthopedics - August 3, 2017 Category: Orthopaedics Authors: Ko JK, Nicholson TA, Hoffler CE, Williams G, Getz C Tags: Orthopedics Source Type: research

Clinical Manifestations and Diagnostic Evaluation of Opioid Allergy Labels - A Review.
Authors: Kalangara J, Potru S, Kuruvilla M Abstract While opioids represent one of the most common medication allergy labels, these labels are often unsubstantiated in clinical practice. The removal of erroneous opioid allergy labels has a unique importance in the population with acute or chronic pain. The current approach to patients with pseudo-allergy to opioids is switching to an alternative opioid with less histamine release. Thus, allergy labels to relatively lower potency opioids such as codeine may be feasibly result in the prescription of stronger medications like fentanyl that would otherwise not be indic...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 24, 2019 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research