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Total 602 results found since Jan 2013.

Effects of food allergy on the dietary habits and intake of primary schools' Cypriot children.
Conclusion. Food allergy in Cypriot food allergic children impacts on both the quality and quantity of food choices, probably due to lack of nutritional education regarding proper elimination diet and alternative nutrient sources. PMID: 28752722 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - July 30, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin.
CONCLUSION: Shrimp arginine kinase and sarcoplasmic calcium-binding protein are minor allergens sensitizing only 10%-15% of Italian shrimp-allergic patients, but are clinically relevant. Hemocyanin is a clinically relevant high molecular weight shrimp allergen possibly cross-reacting to house dust mite. PMID: 25224947 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - March 9, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity
Conclusion Tropomyosin and sarcoplasmic-calcium-binding-protein sensitization is associated with clinical reactivity to shrimp. Myosin light chain testing may help in the diagnosis of clinical reactivity. Arginine kinase and hemocyanin appear to be cross-reacting allergens between shrimp and arthropods. Detection of IgE to these allergens and some of their epitopes may be better diagnostic tools in the routine workup of shrimp allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 13, 2015 Category: Allergy & Immunology Source Type: research

Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity
Conclusion Tropomyosin and sarcoplasmic-calcium-binding-protein sensitization is associated with clinical reactivity to shrimp. Myosin light chain testing may help in the diagnosis of clinical reactivity. Arginine kinase and hemocyanin appear to be cross-reacting allergens between shrimp and arthropods. Detection of IgE to these allergens and some of their epitopes may be better diagnostic tools in the routine workup of shrimp allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2015 Category: Allergy & Immunology Source Type: research

A general strategy for the generation of hypoallergenic molecules for the immunotherapy of fish allergy
Surveys in the United States and Europe show that up to 0.5% of the population suffers from fish allergy, which is a frequent cause of severe and life-threatening anaphylactic reactions. Parvalbumin, a small calcium-binding protein, which is extremely resistant to heat and digestion, represents the major fish allergen. Because of the high degree of sequence homologies and cross-reactivities between parvalbumins from different fish species, consumption of various fish species leads to clinical symptoms in fish-allergic patients. Several immunotherapy trials investigating the applicability of recombinant hypoallergenic vacci...
Source: Journal of Allergy and Clinical Immunology - June 13, 2013 Category: Allergy & Immunology Authors: Ines Swoboda, Nadja Balic, Christoph Klug, Margit Focke, Milena Weber, Susanne Spitzauer, Angela Neubauer, Santiago Quirce, Nikolaos Douladiris, Nikolaos G. Papadopoulos, Rudolf Valenta Tags: Letters to the Editor Source Type: research

Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis).
CONCLUSION: Ten allergens were identified as allergens in various organs, and they are suggested as novel allergens in banana shrimp. The major allergen in muscle and shell from this shrimp is arginine kinase, whereas the major allergen in the ovary is vitellogenin. PMID: 24996992 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 1, 2014 Category: Allergy & Immunology Authors: Khanaruksombat S, Srisomsap C, Chokchaichamnankit D, Punyarit P, Phiriyangkul P Tags: Ann Allergy Asthma Immunol Source Type: research

Shellfish Allergy: a Comprehensive Review
Abstract Shellfish allergy is of increasing concern, as its prevalence has risen in recent years. Many advances have been made in allergen characterization. B cell epitopes in the major allergen tropomyosin have been characterized. In addition to tropomyosin, arginine kinase, sarcoplasmic calcium-binding protein, and myosin light chain have recently been reported in shellfish. All are proteins that play a role in muscular contraction. Additional allergens such as hemocyanin have also been described. The effect of processing methods on these allergens has been studied, revealing thermal stability and resistance to...
Source: Clinical Reviews in Allergy and Immunology - October 1, 2015 Category: Allergy & Immunology Source Type: research

Combined Blockade of the Histamine H1 and H4 Receptor Suppresses Peanut‐Induced Intestinal Anaphylaxis by Regulating Dendritic Cell Function
ConclusionBlockade of both H1R and H4R in the challenge phase had additive effects in preventing the intestinal consequences of peanut sensitization and challenge. These effects were mediated through limitation of mesenteric lymph node and intestinal DC accumulation and function. Identification of this histamine‐H1R/H4R‐DC‐CD4+ T cell axis provides new insights into the development of peanut‐induced intestinal allergic responses and for prevention and treatment of peanut allergy.This article is protected by copyright. All rights reserved.
Source: Allergy - April 4, 2016 Category: Allergy & Immunology Authors: Meiqin Wang, Junyan Han, Joanne Domenico, Yoo Seob Shin, Yi Jia, Erwin W. Gelfand Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Milk Allergy Tied to Lower Bone Density in ChildrenMilk Allergy Tied to Lower Bone Density in Children
BMD and calcium intake were lower in prepubertal children with persistent cow's milk allergy compared with their peers, a new study has found. Medscape Medical News
Source: Medscape Allergy Headlines - April 20, 2016 Category: Allergy & Immunology Tags: Pediatrics News Source Type: news

Combined Blockade of the Histamine H1 and H4 Receptor Suppresses Peanut ‐Induced Intestinal Anaphylaxis by Regulating Dendritic Cell Function
ConclusionBlockade of both H1R and H4R in the challenge phase had additive effects in preventing the intestinal consequences of peanut sensitization and challenge. These effects were mediated through limitation of mesenteric lymph node and intestinal DC accumulation and function. Identification of this histamine‐H1R/H4R‐DC‐CD4+ T cell axis provides new insights into the development of peanut‐induced intestinal allergic responses and for prevention and treatment of peanut allergy.This article is protected by copyright. All rights reserved.
Source: Allergy - April 4, 2016 Category: Allergy & Immunology Authors: Meiqin Wang, Junyan Han, Joanne Domenico, Yoo Seob Shin, Yi Jia, Erwin W. Gelfand Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Antihypertensive medication use is associated with increased organ system involvement and hospitalization in emergency department patients with anaphylaxis
Conclusions: In emergency department anaphylaxis patients, antihypertensive medication use is associated with increased organ system involvement and increased odds of hospital admission, independent of age, gender, suspected trigger, or preexisting lung disease.
Source: Journal of Allergy and Clinical Immunology - February 28, 2013 Category: Allergy & Immunology Authors: Sangil Lee, Erik P. Hess, David M. Nestler, Venkatesh R. Bellamkonda Athmaram, M. Fernanda Bellolio, Wyatt W. Decker, James T.C. Li, John B. Hagan, Veena Manivannan, Samuel C. Vukov, Ronna L. Campbell Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Vitamin D in acute kidney injury.
Abstract Vitamin D deficiency is common in critically ill patients and associated with increased mortality, as well as an increased risk of acute kidney injury. The occurrence of acute kidney injury by itself substantially increases critical care mortality. In addition to regulating calcium and phosphorus homeostasis and bone metabolism, vitamin D has pleotropic effects on the immune response. Potential mechanisms of how a deficiency in vitamin D could predispose individuals to increased risk of acute renal failure include dysregulation of the immune system, predisposing patients to sepsis, endothelial dysfunction...
Source: Inflammation and Allergy Drug Targets - June 13, 2013 Category: Allergy & Immunology Authors: Braun AB, Christopher KB Tags: Inflamm Allergy Drug Targets Source Type: research

Prevalence and risk factors of vitamin D deficiency in critically ill patients.
Abstract Vitamin D (Vit D) is well known for its traditional role in calcium and bone homeostasis. Sun exposure and diet are essential for Vit D synthesis and intake. However, the association of Vit D deficiency with various diseases has held the attention of clinicians. Of note, Vit D has pleiotropic effects that could be involved in the optimal functioning of many organ systems. Several epidemiologic studies have documented widespread Vit D deficiency worldwide. Vit D deficiency is also frequent in hospitalized patients. Recently, publications have suggested a high prevalence of Vit D deficiency in critically il...
Source: Inflammation and Allergy Drug Targets - June 13, 2013 Category: Allergy & Immunology Authors: Sauneuf B, Brunet J, Lucidarme O, du Cheyron D Tags: Inflamm Allergy Drug Targets Source Type: research

Elevation of S100 calcium binding protein A9 in sputum of neutrophilic inflammation in severe uncontrolled asthma.
CONCLUSION: S100A9 in sputum may be a biomarker of neutrophilic inflammation in severe UA. PMID: 24054362 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 25, 2013 Category: Allergy & Immunology Authors: Lee TH, Jang AS, Park JS, Kim TH, Choi YS, Shin HR, Park SW, Uh ST, Choi JS, Kim YH, Kim Y, Kim S, Chung IY, Jeong SH, Park CS Tags: Ann Allergy Asthma Immunol Source Type: research