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Total 769 results found since Jan 2013.
Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy
Allergic reactions to drugs are a serious public health concern. In 2013, the Division of Allergy, Immunology, and Transplantation of the National Institute of Allergy and Infectious Diseases sponsored a workshop on drug allergy. International experts in the field of drug allergy with backgrounds in allergy, immunology, infectious diseases, dermatology, clinical pharmacology, and pharmacogenomics discussed the current state of drug allergy research. These experts were joined by representatives from several National Institutes of Health institutes and the US Food and Drug Administration.
Source: Journal of Allergy and Clinical Immunology - August 1, 2015 Category: Allergy & Immunology Authors: Lisa M. Wheatley, Marshall Plaut, Julie M. Schwaninger, Aleena Banerji, Mariana Castells, Fred D. Finkelman, Gerald J. Gleich, Emma Guttman-Yassky, Simon A.K. Mallal, Dean J. Naisbitt, David A. Ostrov, Elizabeth J. Phillips, Werner J. Pichler, Thomas A.E. Tags: Reviews and feature article Source Type: research
Food Allergy: Update on Prevention and Tolerance
Of the many possible hypotheses which explain the recent rise in childhood food allergy, the dual allergen exposure hypothesis has been the most extensively investigated. This chapter serves as a review and update on the prevention of food allergy, and focuses on recently published Randomized Controlled Trials (RCTs) exploring the efficacy of oral tolerance induction in infancy for the prevention of food allergy. As a result of these RCTs, National Institutes of Health (NIH) recommendations now actively encourage the early introduction of peanut for the prevention of peanut allergy and other countries/settings recommend th...
Source: Journal of Allergy and Clinical Immunology - November 27, 2017 Category: Allergy & Immunology Authors: George Du Toit, Hugh Sampson, Marshall Plaut, Wesley Burks, Cezmi Akdis, Gideon Lack Source Type: research
Allergy and immune disorders can result from mutations in gene involved in sugar metabolism
Researchers at the National Institutes of Health (NIH) have identified a new genetic syndrome characterized by a constellation of health problems, including severe allergy, immune deficiency, autoimmunity and motor and neurocognitive impairment. The researchers, led by scientists at the NIH's National Institute of Allergy and Infectious Diseases (NIAID), observed that the syndrome's diverse symptoms are the result of mutations in a single gene associated with sugar metabolism.
Source: Health News from Medical News Today - March 6, 2014 Category: Consumer Health News Tags: Allergy Source Type: news
Association of Serum Levels of Pentraxin-3, M-ficolin, and Surfactant Protein A with the Severity of Ischemic Stroke.
Abstract
Stroke is one of the most leading causes of death and disability in the world. Complement system activation contributes to pathogenesis and neuronal damage following stroke. There are no defined biological serum markers to determine the severity of stroke in acute phases. The purpose of current study was to determine the association of three complement activators, namely Pentraxin-3 (PTX3),M-ficolin, and Surfactant protein A (SPA) with the severity of ischemic stroke. This cross-sectional study was done on 82 patients diagnosed with ischemic stroke at 24-96 hours of initiation of the clinical symptoms dur...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2017 Category: Allergy & Immunology Authors: Kouchaki E, Babamohammadi A, Nikoueinejad H, Sehat M Tags: Iran J Allergy Asthma Immunol Source Type: research
How To Desensitize Your Child To A Food Allergy
The news is suddenly full of new recommendations on how to keep your baby allergy free. But what if it is too late to prevent allergies in your household? What if you’ve already seen your little one break out in hives, swell into a bawling bruised tomato or some other scary reaction? Have the great advances in allergy understanding just come too late for you and your kid?
No. Especially if your child is still relatively young.
The newest treatment, under study by experts at Northwestern University in Chicago, involves educating the immune system on the safety of, say, peanuts, by attaching peanut proteins to wh...
Source: Healthy Living - The Huffington Post - June 13, 2017 Category: Consumer Health News Source Type: news
Peanut allergy prevention strategy is nutritionally safe, NIH-funded study shows
(NIH/National Institute of Allergy and Infectious Diseases) Introducing peanut-containing foods during infancy as a peanut allergy prevention strategy does not compromise the duration of breastfeeding or affect children's growth and nutritional intakes, new findings show. The work, funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is published online on June 10 in the Journal of Allergy and Clinical Immunology.
Source: EurekAlert! - Medicine and Health - June 10, 2016 Category: Global & Universal Source Type: news
NIH designates $42.7 million for food allergy research consortium
(NIH/National Institute of Allergy and Infectious Diseases) The National Institutes of Health intends to award $42.7 million over seven years to the Consortium of Food Allergy Research (CoFAR) so it may continue evaluating new approaches to treat food allergy. Established in 2005, the CoFAR has been continuously funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH. The first year of funding has been awarded, and awards will be made in subsequent years based on the availability of funds.
Source: EurekAlert! - Medicine and Health - March 29, 2017 Category: Global & Universal Source Type: news
Where you live in the US does not affect prevalence of allergies
In the largest, most comprehensive, nationwide study to examine the prevalence of allergies from early childhood to old age, scientists from the National Institutes of Health report that allergy prevalence is the same across different regions of the United States, except in children 5 years and younger."Before this study, if you would have asked 10 allergy specialists if allergy prevalence varied depending on where people live, all 10 of them would have said yes, because allergen exposures tend to be more common in certain regions of the U.S.," said Darryl Zeldin, M.D.
Source: Health News from Medical News Today - March 7, 2014 Category: Consumer Health News Tags: Allergy Source Type: news
Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8–deficient patients
Dedicator of cytokinesis 8 (DOCK8) deficiency is a highly morbid combined immunodeficiency that features recurrent sinopulmonary infections, viral skin infections, and severe food allergies.1,2 Hematopoietic stem cell transplantation (HSCT) cures infection susceptibility in patients with DOCK8 deficiency.3-7 Whether HSCT also cures food allergy has not been systematically examined in human subjects.8 To gain insight into the etiopathogenesis of food allergy and its potential treatment, we studied food allergy in 12 DOCK8-deficient patients who underwent HSCT at the National Institutes of Health (NIH) Clinical Center.
Source: Journal of Allergy and Clinical Immunology - January 28, 2016 Category: Allergy & Immunology Authors: Corinne S. Happel, Kelly D. Stone, Alexandra F. Freeman, Nirali N. Shah, Angela Wang, Jonathan J. Lyons, Pamela A. Guerrerio, Dennis D. Hickstein, Helen C. Su Tags: Letter to the Editor Source Type: research
Infant gut microbiome appears to shape allergy risk by altering immune responses
(NIH/National Institute of Allergy and Infectious Diseases) The microbial communities, or microbiota, that naturally colonize the digestive tract in very young infants can affect their risk of later developing childhood allergies and asthma. Scientists now have identified a specific type of microbiota composition and corresponding metabolic environment in the neonatal gut that appears to influence immune cell populations and promote allergy and asthma development. The work was funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Source: EurekAlert! - Medicine and Health - September 12, 2016 Category: Global & Universal Source Type: news
Erratum
In the article entitled “Immunodominance in allergic T-cell reactivity to Japanese cedar in different geographic cohorts” (Ann Allergy Asthma Immunol 2016;117:680-689), acknowledgment of funding sources was inadvertently omitted from the article. Funding for the article was provided in part by ALK-Abello A/S (Horsholm, Denmark) and with federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, under grant number U19 AI100275.
Source: Annals of Allergy, Asthma and Immunology - January 15, 2017 Category: Allergy & Immunology Tags: Erratum Source Type: research
Lyndra gets boost for drug delivery platform from U.S. allergy institute
Lyndra said today that it won a 5-year grant from the National Institute of Allergy and Infectious Diseases, a branch of the National Institutes of Health. The grant is slated to support the formulation and preclinical development of a once-weekly oral HIV treatment.
The Watertown, Mass.-based company makes use of a sustained-release technology developed by Robert Langer at the Massachusetts Institute of Technology. A star-shaped pill loaded with drugs remains in the gastric cavity after it’s been swallowed for a pre-determined length of time. After the drugs have been released, the pill splits into small pieces and saf...
Source: Mass Device - May 2, 2017 Category: Medical Equipment Authors: Sarah Faulkner Tags: Drug-Device Combinations Funding Roundup Pharmaceuticals Research & Development lyndra Source Type: news
NIAID (National Institute of Allergy and Infectious Diseases)'s Antibiotic Resistance Research Framework: Current Status and Future Directions 2019
Source: National Institute of Allergy and Infectious Diseases [National Institutes of Health] (NIAID). Published: 12/2019.
This 20-page report describes the National Institute of Allergy and Infectious Diseases ’s portfolio of basic, translational, and clinical research in antimicrobial resistance, and outlines an updated array of innovative approaches based on the latest scientific advances and research opportunities to address this urgent public health priority. It details scientific approaches to anti microbial resistance research, the antibiotic development pipeline, and Innovative approaches to addressing the antib...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - December 1, 2019 Category: International Medicine & Public Health Source Type: news
In Clinical Study, Peanut Therapy Shows Promise In Treating Peanut Allergy
A new study supported by the National Institutes of Health (NIH) suggests that sublingual immunotherapy (SLIT) can reduce the allergic response to peanut in adolescents and adults. SLIT is a treatment approach in which, under medical supervision, people place a small amount of allergen under the tongue to decrease their sensitivity to the allergen...
Source: Health News from Medical News Today - January 9, 2013 Category: Consumer Health News Tags: Allergy Source Type: news
