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Infectious Disease: Tuberculosis

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Total 482 results found since Jan 2013.

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Neonatal BCG has no effect on allergic sensitization and suspected food allergy until 13 months
ConclusionIn this randomized clinical trial neonatal BCG had no significant effect on suspected food allergy or on sensitization at 13 months of age.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - June 29, 2017 Category: Allergy & Immunology Authors: Lisbeth Marianne Th østesen, Henrik Fomsgaard Kjaer, Gitte Thybo Pihl, Thomas Nørrelykke Nissen, Nina Marie Birk, Jesper Kjærgaard, Aksel Karl Georg Jensen, Peter Aaby, Annette Wind Olesen, Lone Graff Stensballe, Dorthe Lisbeth Jeppesen, Christine Stab Tags: Original Source Type: research

Neonatal BCG has no effect on allergic sensitization and suspected food allergy until 13  months
ConclusionIn this randomized clinical trial, neonatal BCG had no significant effect on suspected food allergy or on sensitization at 13 months of age.
Source: Pediatric Allergy and Immunology - September 5, 2017 Category: Allergy & Immunology Authors: Lisbeth Marianne Th østesen, Henrik Fomsgaard Kjaer, Gitte Thybo Pihl, Thomas Nørrelykke Nissen, Nina Marie Birk, Jesper Kjærgaard, Aksel Karl Georg Jensen, Peter Aaby, Annette Wind Olesen, Lone Graff Stensballe, Dorthe Lisbeth Jeppesen, Christine Stab Tags: ORIGINAL ARTICLE Source Type: research

Perceptions of Severe Asthma and Asthma-COPD Overlap Syndrome Among Specialists: A Questionnaire Survey.
CONCLUSIONS: Specialists had diverse perceptions and clinical practices regarding severe asthma and ACOS patients. This heterogeneity must be considered in future studies and strategy development for severe asthma and ACOS. PMID: 29676069 [PubMed]
Source: Allergy, Asthma and Immunology Research - April 22, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Papillon Lefevre Syndrome and footsteps of mycobacterium tuberculosis.
Abstract Papillon Lefevre Syndrome ( PLS ) is a very rare genetic syndrome that only less than 500 cases have reported in the world. Patients have a typical cutaneous involvement with hyperkeratosis especially on the soles and palms and early shedding of primary teeth. Internal organs involvement such as liver abscess has been presented as case reports. This is for the first time that a genetically documented PLS with footsteps of mycobacterium tuberculosis in liver and kidney will report. PMID: 24659165 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - March 29, 2014 Category: Allergy & Immunology Authors: Zandieh F, Mirsaed Ghazi B, Izadi A, Gharegozlu M, Aghajani M, Sheikh M Tags: Iran J Allergy Asthma Immunol Source Type: research

Cutaneous Adverse Drug Reactions Caused By Antituberculosis Drugs.
Abstract Multidrug antituberculosis regimen is associated with diverse clinical patterns of cutaneous adverse drug reactions (CADR), ranging from mild and moderate such as pruritus, maculopapular exanthems, lichenoid eruptions, fixed drug eruptions and urticaria to severe and even life threatening ones like acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome and toxic epidermal necrolysis. These adverse reactions to antituberculosis drugs are commonly observed adverse events. This is of particular importance for high HIV prevalence settings and developing countries where tuberculosis is com...
Source: Inflammation and Allergy Drug Targets - July 17, 2014 Category: Allergy & Immunology Authors: Rezakovic S, Pastar Z, Kostovic K Tags: Inflamm Allergy Drug Targets Source Type: research

Immunopathology of sarcoidosis.
Abstract The immunopathology of sarcoidosis remains elusive despite years of research into this multiorgan disease.However, recent studies have provided new insights into the genetics and immune components involved in the clinical manifestation of the disease. Granulomatous inflammation is due to the host immune response to a persistent poorly degradable unknown antigen.Mycobacterium tuberculosis (MTB) is the major disease driver in many patients. The immune mechanisms that cause this disease start with the antigenic stimulus, followed by T-cell, macrophage and dendritic cell activation via a classic MHC II-mediat...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 31, 2014 Category: Allergy & Immunology Authors: Mortaz E, Masjedi MR, Tabarsi P, Pourabdollah M, Adcock IM Tags: Iran J Allergy Asthma Immunol Source Type: research

Increased Expression of Forkhead Box Protein 3 Gene of Regulatory T Cells in Patients with Active Tuberculosis.
According to this study, the increased Foxp3 gene expression in patients with TB was observed and this may play as a contributing factor to suppression of Th1-type immune responses. PMID: 25198706 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - September 8, 2014 Category: Allergy & Immunology Authors: Beiranvand E, Abediankenari S, Rezaei MS, Khani S, Sardari S, Beiranvand B Tags: Inflamm Allergy Drug Targets Source Type: research

A case of serum sickness-like reaction and anaphylaxis - induced simultaneously by rifampin.
Authors: Kim DH, Choi YH, Kim HS, Yu JE, Koh YI Abstract Rifampin is commonly used as a first-line anti-tuberculosis drug, but it can induce a serum sickness-like reaction or anaphylaxis. However, it is possible for 1 drug antigen to induce 2 or more simultaneous immunologic reactions. Here, we report a case of a serum-sickness-like reaction and anaphylaxis induced concurrently by rifampin. A 25-year-old male presented with high fever and a maculopapular rash with vesicles on the hands, which developed 2 weeks following regular administration of anti-tuberculosis drugs for tuberculous meningitis, including rifampin...
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Association between Interleukin-1 Receptor Antagonist (IL1RN) Variable Number of Tandem Repeats (VNTR) Polymorphism and Pulmonary Tuberculosis.
In this study we aimed to examine the possible association between the variable number of tandem repeats (VNTR) of the IL-1 receptor antagonist (IL1RN) gene and pulmonary tuberculosis (TB) in a sample of Iranian population. Our study is a case-control study and we examined the VNTR of the IL1RN gene in 265 PTB and 250 healthy subjects by PCR. Neither the overall chi-square comparison of PTB and control subjects nor the logistic regression analysis indicated any association between VNTR IL1RN polymorphism and PTB. Our data suggest that VNTR IL1RN polymorphism may not be associated with the risk of PTB in a sample of Iranian...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 26, 2014 Category: Allergy & Immunology Authors: Hashemi M, Naderi M, Ebrahimi M, Amininia S, Bahari G, Taheri M, Eskandari-Nasab E, Ghavami S Tags: Iran J Allergy Asthma Immunol Source Type: research

Flow cytometry applications in the study of immunological lung disorders.
Abstract The use of flow cytometry in the clinical laboratory has grown substantially in the past decade. Flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. For example, it is possible to detect the cell size and granularity, aspects of DNA and RNA content and the presence of cell surface and nuclear markers which are used to characterize the phenotype of single cells. Flow cytometry has been used for the immunophenotyping of a variety of specimens including whole blood, bone marrow, serous cavity fluids, (cerebrospinal fluid) CSF, ur...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 26, 2014 Category: Allergy & Immunology Authors: Mortaz E, Gudarzi H, Tabarsi P, M Adcock I, Masjedi MR, Jamaati HR, Garssen J, Velayati AA, A Redegeld F Tags: Iran J Allergy Asthma Immunol Source Type: research

Immediate-type hypersensitivity reactions due to antituberculosis drugs: a successful readministration protocol.
CONCLUSION: Immediate-type allergic reactions from antituberculosis drugs are not rare and not related to disease or treatment characteristics. The protocols used in this study provide a useful and safe method for readministration of culprit drugs to patients with antituberculosis drug hypersensitivity. PMID: 25981840 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 14, 2015 Category: Allergy & Immunology Authors: Buhari GK, Keren M, Dursun AB, Güler M, Dulkar G, Kalaç N, Özkara Ş, Erkekol FÖ Tags: Ann Allergy Asthma Immunol Source Type: research

Formulation of Nanoparicles Against TB - A Review.
Authors: Kataria M, Sethi M, Kaur J, Punia S, Kumar K Abstract Tuberculosis is a major public health concern. The present article reviews the current updates on the usage of nanoparticles against tuberculosis and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the TB management. The drug delivery systems involving nanoparticles are suitable against chronic diseases such as tuberculosis. Polymers in many forms like liposomes, dendrimers, Nanoemulsions can be used as synthetic and natural carriers for first line and second line drugs employed for chemotherapy. Not...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - September 30, 2015 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Association of TAP1 and TAP2 Gene Polymorphisms with Susceptibility to Pulmonary Tuberculosis.
In conclusion, our findings proposed that TAP gene polymorphisms might be associated with PTB susceptibility among patients in Zahedan, southeast Iran. PMID: 26996113 [PubMed - as supplied by publisher]
Source: Iranian Journal of Allergy, Asthma and Immunology - January 31, 2016 Category: Allergy & Immunology Authors: Naderi M, Hashemi M, Amininia S Tags: Iran J Allergy Asthma Immunol Source Type: research

Allergic bronchopulmonary aspergillosis complicating Swyer-James-Macleod's syndrome: case report and review of literature.
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research