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Infectious Disease: Gastroenteritis

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Total 621 results found since Jan 2013.

Profiles of IgE Sensitization to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20 in Korean House Dust Mite Allergy Patients.
CONCLUSIONS: Der f 2 was the most frequently sensitized allergen among the HDM-sensitized respiratory and AD patients in Korea, and the combination of the group 1 and 2 major allergens increased the diagnostic sensitivity. Minor allergens did not significantly improve diagnostic sensitivity. However, further studies are needed to analyze the relationship between sensitization to other HDM allergens and the disease entity of the HDM allergy. PMID: 25749773 [PubMed - as supplied by publisher]
Source: Allergy, Asthma and Immunology Research - March 12, 2015 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Fecal Microbiome and Food Allergy in Pediatric Atopic Dermatitis: A Cross-Sectional Pilot Study
Conclusions: In this pilot study, we identified a microbial signature in children with AD that discriminates between the absence and presence of food allergy. Future studies are needed to confirm our findings.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - January 24, 2018 Category: Allergy & Immunology Source Type: research

Development of a Hypoallergenic Recombinant Parvalbumin for First-in-Man Subcutaneous Immunotherapy of Fish Allergy
Conclusion: The GMP drug product developed for treatment of fish allergy has the characteristics targeted for in FAST: i.e. hypoallergenicity with retained immunogenicity. These results have warranted first-in-man immunotherapy studies to evaluate the safety of this innovative vaccine.Int Arch Allergy Immunol 2015;166:41-51
Source: International Archives of Allergy and Immunology - February 28, 2015 Category: Allergy & Immunology Source Type: research

Alteration of Allergen Fold of Bos d 5 into a Hypoallergenic Vaccine for Immunotherapy of Cow ’s Milk Allergy
Conclusion: Thus, we developed a new strategy, which was based on rational molecular reassembly for allergen-specific immunotherapy (AIT) of CMA and food allergy.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - August 12, 2021 Category: Allergy & Immunology Source Type: research

Clinical presentation and referral characteristics of food protein-induced enterocolitis syndrome in the United Kingdom.
CONCLUSION: In the United Kingdom, FPIES typically has its onset at 8 months. Patients experience a delay of 12 months in the diagnosis of FPIES and frequently have multiple episodes and interim diagnoses. A great need remains for enhanced education of medical practitioners dealing with children about the varied presentations of FPIES. PMID: 25065570 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 22, 2014 Category: Allergy & Immunology Authors: Ludman S, Harmon M, Whiting D, du Toit G Tags: Ann Allergy Asthma Immunol Source Type: research

Allergenic Characterization of a Novel Allergen, Homologous to Chymotrypsin, from German Cockroach.
CONCLUSIONS: A novel allergen homologous to chymotrypsin was identified from the German cockroach and was cross-reactive with Der f 6. PMID: 25749759 [PubMed - as supplied by publisher]
Source: Allergy, Asthma and Immunology Research - March 12, 2015 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

A Recombinant Sal k 1 Isoform as an Alternative to the Polymorphic Allergen from Salsola kali Pollen for Allergy Diagnosis
Conclusions: rSal k 1 expressed in bacteria retains intact structural and immunological properties in comparison to the pollen-derived allergen. It spans the immunological properties of most of the isoforms found in pollen, and it might substitute natural Sal k 1 in clinical diagnosis.Int Arch Allergy Immunol 2015;167:83-93
Source: International Archives of Allergy and Immunology - July 23, 2015 Category: Allergy & Immunology Source Type: research

Molecular Cloning and Expression of a New Allergen of Acacia farnesiana (Aca f 2).
This study aimed to produce and purify the A. farnesiana pollen profilin (Aca f 2) and evaluate its nucleotide sequence homology with profilins of common allergenic plants to predict allergenic cross-reactivity. Thirty-nine patients who were allergic to Acacia pollens were included in the study. Cloning of Acacia profilin-coding sequence was performed by polymerase chain reaction using primers from Acacia pollen RNA. The cDNA of Acacia pollen profilin was then expressed in Escherichia coli using pET-21b(+) vector and purified by metal affinity chromatography. Immunoreactivity of the recombinant Acacia profilin (rAca f 2) ...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 1, 2015 Category: Allergy & Immunology Authors: Sepahi N, Khodadadi A, Assarehzadegan M, Amini A, Zarinhadideh F, Ali-Sadeghi H Tags: Iran J Allergy Asthma Immunol Source Type: research

Ani s 11-Like Protein Is a Pepsin- and Heat-Resistant Major Allergen of Anisakis spp. and a Valuable Tool for Anisakis Allergy Component-Resolved Diagnosis
Conclusions: These data indicate that the Ani s 11-like protein is a pepsin- and heat-resistant major allergen (Ani s 11.0201) of Anisakis spp. and a valuable tool for Anisakis allergy component-resolved diagnosis.Int Arch Allergy Immunol 2016;169:108-112
Source: International Archives of Allergy and Immunology - April 6, 2016 Category: Allergy & Immunology Source Type: research

Molecular Cloning and Expression of Pro J 1: A New Allergen of Prosopis Juliflora Pollen.
Abstract Pollen from mesquite (Prosopis juliflora) is one of the important causes of immediate hypersensitivity reactions in the arid and semi-arid regions of the world. The aim of present study is to produce and purify the recombinant form of allergenic Ole e 1-like protein from the pollen of this allergenic tree. Immunological and cross-inhibition assays were performed for the evaluation of IgE-binding capacity of purified recombinant protein. For molecular cloning, the coding sequence of the mesquite Ole e 1-like protein was inserted into pTZ57R/T vector and expressed in Escherichia coli using the vector pET-21...
Source: Iranian Journal of Allergy, Asthma and Immunology - March 31, 2016 Category: Allergy & Immunology Authors: Dousti F, Assarehzadegan MA, Morakabati P, Khosravi GR, Akbari B Tags: Iran J Allergy Asthma Immunol Source Type: research

Cat-NPC2, a Newly Identified Allergen, With High Cross-Reactivity to Can f 7.
CONCLUSIONS: In the study, a novel cat allergen, belonging to the NPC2 protein family, was identified and characterized at both molecular and immunological levels. The study will offer a deeper understanding of cat allergens and improve a component-resolved diagnosis in pet allergy. PMID: 33191681 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

A phase 1 study of heat/phenol‐killed, E. coli‐encapsulated, recombinant modified peanut proteins Ara h 1, Ara h 2, and Ara h 3 (EMP‐123) for the treatment of peanut allergy
ConclusionsRectal administration of EMP‐123 resulted in frequent adverse reactions, including severe allergic reactions in 20%.
Source: Allergy - April 29, 2013 Category: Allergy & Immunology Authors: R. A. Wood, S. H. Sicherer, A. W. Burks, A. Grishin, A. K. Henning, R. Lindblad, D. Stablein, H. A. Sampson Tags: Original Article Source Type: research

Green Tea Catechins Quench The Fluorescence of Bacteria-Conjugated Alexa Fluor Dyes.
Abstract Accumulating evidence suggest that Green tea polyphenolic catechins, especially the (-)-epigallocatechin gallate (EGCG), can be cross-linked to many proteins, and confer a wide range of anti-bacterial activities possibly by damaging microbial cytoplasmic lipids and proteins. At the doses that conferred protection against lethal polymicrobial infection (induced by cecal ligation and puncture), EGCG significantly reduced bacterial loads particularly in the liver and lung. To elucidate its bactericidal mechanisms, we determined whether EGCG affected the fluorescence intensities of bacteria-conjugated Alexa F...
Source: Inflammation and Allergy Drug Targets - September 3, 2013 Category: Allergy & Immunology Authors: Zhao L, Li W, Zhu S, Tsai S, Li J, Tracey KJ, Wang P, Fan S, Sama AE, Wang H Tags: Inflamm Allergy Drug Targets Source Type: research

The Gut Microbiome.
Abstract Since the discovery and use of the microscope in the 17th century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may cause diabetes and obesity. The human microbiome has developed by modulating or avoiding inflammatory responses; the host senses bacterial presence through cell surface sensors (the Toll-like receptors) as well as by refining mucous barriers as passive defense ...
Source: Inflammation and Allergy Drug Targets - June 23, 2014 Category: Allergy & Immunology Authors: Actis GC Tags: Inflamm Allergy Drug Targets Source Type: research